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期刊文章列表

  • Xiang Wang1,2,Xinxin Chen3,Wenqian Zhou1,2,Hongbo Men1,2,Terigen Bao1,2,Yike Sun1,2,Quanwei Wang2,Yi Tan1,4,Bradley B.Keller4,5,6,Qian Tong2,Yang Zheng2,Lu Cai1,4(Pediatric Research Institute,Department of Pediatrics,University of Louisville School of Medicine;Department of Cardiovascular Disease,the First Hospital of Jilin University;Department of Burn Surgery,First Hospital of Jilin University,Jilin University;Department of Pharmacology and Toxicology,University of Louisville School of Medicine;Pediatric Heart Research Program,Cardiovascular Innovation Institute,University of Louisville School of Medicine;Cincinnati Children's Heart Institute,Greater Louisville and Western Kentucky Practice).Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK/NRF2 pathways[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Danyu Du1,Chan Liu1,Mengyao Qin1,Xiao Zhang1,Tao Xi2,Shengtao Yuan3,Haiping Hao1,4,5,Jing Xiong1(Department of Pharmacology,School of Pharmacy,China Pharmaceutical University;Research Center of Biotechnology,School of Life Science and Technology,China Pharmaceutical University;Jiangsu Key Laboratory of Drug Screening,China Pharmaceutical University;State Key Laboratory of Natural Medicines,China Pharmaceutical University;Key Laboratory of Drug Metabolism and Pharmacokinetics,China Pharmaceutical University).Metabolic dysregulation and emerging therapeutical targets for hepatocellular carcinoma[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Makhloufi Zoulikha1,Qingqing Xiao1,George Frimpong Boafo1,Marwa A.Sallam2,Zhongjian Chen3,Wei He1,3(Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical University;Department of Industrial Pharmacy,Faculty of Pharmacy,Alexandria University;Shanghai Skin Disease Hospital,Tongji University School of Medicine).Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Qiubing Chen1,2,Qian Li2,Yuqi Liang1,Menghang Zu1,2,Nanxi Chen1,Brandon S.B.Canup3,Liyong Luo4,Chenhui Wang5,Liang Zeng4,Bo Xiao1,2(State Key Laboratory of Silkworm Genome Biology,College of Sericulture,Textile,and Biomass Sciences,Southwest University;Chongqing Key Laboratory of Soft-Matter Material Chemistry and Function Manufacturing,School of Materials and Energy,Southwest University;Department of Chemistry,Center for Diagnostics and Therapeutics,Georgia State University;College of Food Science,Southwest University;Chongqing Key Laboratory of Natural Product Synthesis and Drug Research,School of Pharmaceutical Sciences,Chongqing University).Natural exosome-like nanovesicles from edible tea flowers suppress metastatic breast cancer via ROS generation and microbiota modulation[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Hang Qi1,Yuntao Shi2,Han Wu1,Canyang Niu1,Xiaoying Sun1,3,Ke Wei Wang1,3(Department of Pharmacology,School of Pharmacy,Qingdao University;State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University;Institue of Innovative Drugs,Qingdao University).Inhibition of temperature-sensitive TRPV3 channel by two natural isochlorogenic acid isomers for alleviation of dermatitis and chronic pruritus[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Xin Sun1,Yuhan Shu2,Guiqin Ye3,Caixia Wu4,Mengting Xu2,Ruilan Gao5,Dongsheng Huang3,Jianbin Zhang4(Department of Oncology,Cancer Center of Zhejiang Provincial People's Hospital,Affiliated People's Hospital,Hangzhou Medical College;College of Biomedical Engineering & Instrument Science,Zhejiang University;Key Laboratory of Tumor Molecular Diagnosis and Individualized Medicine of Zhejiang Province,Hangzhou Medical College;Clinical Research Institute,Zhejiang Provincial People's Hospital,Affiliated People's Hospital,Hangzhou Medical College;Department of Hematology,the First Affiliated Hospital of Zhejiang Chinese Medical University).Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylationmediated mitophagy[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Yan Zhang1,2,Pin Lv3,Junmei Ma2,Ning Chen3,Huishan Guo3,Yan Chen4,Xiaoruo Gan3,Rong Wang3,Xuqiang Liu4,Sufang Fan2,Bin Cong1,5,Wenyi Kang4(Hebei Key Laboratory of Forensic Medicine,College of Forensic Medicine,Hebei Medical University;Hebei Food Safety Key Laboratory,Hebei Food Inspection and Research Institute;Cardiovascular Medical Science Center,Department of Cell Biology,Hebei Medical University;National R & D Center for Edible Fungus Processing Technology,Henan University;Research Unit of Digestive Tract Microecosystem Pharmacology and Toxicology,Chinese Academy of Medical Sciences).Antrodia cinnamomea exerts an anti-hepatoma effect by targeting PI3K/AKT-mediated cell cycle progression in vitro and in vivo[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Steven N.Austad1,Scott Ballinger2,Thomas W.Buford3,Christy S.Carter3,Daniel L.Smith Jr4,Victor Darley-Usmar2,Jianhua Zhang2(Department of Biology,University of Alabama at Birmingham;Department of Pathology,University of Alabama at Birmingham;Department of Medicine,University of Alabama at Birmingham;Department of Nutrition Sciences,University of Alabama at Birmingham).Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer’s disease[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Eugenia Trushina1,2,Sergey Trushin1,Md Fayad Hasan1(Department of Neurology,Mayo Clinic;Department of Molecular Pharmacology and Experimental Therapeutics,Mayo Clinic).Mitochondrial complex I as a therapeutic target for Alzheimer’s disease[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Xumin Zhou1,Libin Zou1,Hangyu Liao2,Junqi Luo1,Taowei Yang1,Jun Wu1,Wenbin Chen1,Kaihui Wu1,Shengren Cen1,Daojun Lv3,Fangpeng Shu4,Yu Yang5,Chun Li6,Bingkun Li1,Xiangming Mao1(Department of Urology,Zhujiang Hospital,Southern Medical University;Second Department of Hepatobiliary Surgery,Zhujiang Hospital,Southern Medical University;Department of Urology,Minimally Invasive Surgery Center,the First Affiliated Hospital of Guangzhou Medical University;Department of Urology,Guangzhou Women and Children's Medical Center,Guangzhou Medical University;Department of Urology,Peking University Shenzhen Hospital;Nursing Department,Nanfang Hospital,Southern Medical University).Abrogation of Hn RNP L enhances anti-PD-1 therapy efficacy via diminishing PD-L1 and promoting CD8+ T cell-mediated ferroptosis in castration-resistant prostate cancer[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Kongzhen Hu1,Junqi Li2,Lijuan Wang1,Yong Huang1,3,Li Li1,Shimin Ye1,Yanjiang Han1,Shun Huang1,Hubing Wu1,Jin Su2,4,Ganghua Tang1(Department of Nuclear Medicine,Nanfang Hospital,Southern Medical University;Shenzhen International Institute for Biomedical Research;National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Respiratory Disease,National Clinical Research Center for Respiratory Disease,Guangzhou Institute of Respiratory Health,the First Affiliated Hospital of Guangzhou Medical University).Preclinical evaluation and pilot clinical study of [18F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Yan Yan1,2,Cancan Du1,Xixi Duan1,Xiaohan Yao1,Jiajia Wan1,Ziming Jiang3,Zhongyu Qin4,Wenqing Li1,Longze Pan1,Zhuoyu Gu1,Fazhan Wang1,Ming Wang1,Zhihai Qin1,2,5(Medical Research Center,the First Affiliated Hospital of Zhengzhou University,Zhengzhou University;Academy of Medical Sciences,Zhengzhou University;Department of Urology,the First Affiliated Hospital of Zhengzhou University,Zhengzhou University;Changzhi Medical College;Institute of Biophysics,Chinese Academy of Sciences).Inhibiting collagen Ⅰ production and tumor cell colonization in the lung via miR-29a-3p loading of exosome-/liposome-based nanovesicles[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Benjamin R.Troutwine1,2,Laylan Hamid2,Colton R.Lysaker2,3,Taylor A.Strope2,3,Heather M.Wilkins1,2,3(Department of Neurology University of Kansas Medical Center;University of Kansas Alzheimer's Disease Center;Department of Biochemistry and Molecular Biology,University of Kansas Medical Center).Apolipoprotein E and Alzheimer’s disease[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Shenghua Gao1,Tianguang Huang1,Letian Song1,Shujing Xu1,Yusen Cheng1,Srinivasulu Cherukupalli1,Dongwei Kang1,2,Tong Zhao1,Lin Sun1,Jian Zhang1,Peng Zhan1,2,Xinyong Liu1,2(Department of Medicinal Chemistry,Key Laboratory of Chemical Biology,Ministry of Education,School of Pharmaceutical Sciences,Cheeloo College of Medicine,Shandong University;China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province).Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Lifang Zhao,Hongyan Zhang,Xueqing Liu,Shan Xue,Dongfang Chen,Jing Zou,Handong Jiang(Department of Respiratory and Critical Care Medicine,Ren Ji Hospital,School of Medicine,Shanghai Jiao Tong University).TGR5 deficiency activates antitumor immunity in non-small cell lung cancer via restraining M2 macrophage polarization[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Tao Su1,Suchao Huang1,Yanmin Zhang1,Yajuan Guo1,Shuwei Zhang1,Jiaji Guan1,Mingjing Meng1,Linxin Liu1,Caiyan Wang1,Dihua Yu2,Hiu-Yee Kwan3,Zhiying Huang1,Qiuju Huang1,Elaine Lai-Han Leung4,Ming Hue5,Ying Wang1,Zhongqiu Liu1,4,Linlin Lu1,4(Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People's Republic of China,Guangzhou University of Chinese Medicine;Department of Molecular and Cellular Oncology,the University of Texas MD Anderson Cancer Center;School of Chinese Medicine,Hong Kong Baptist University;State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology;Department of Pharmacological and Pharmaceutical Sciences,University of Houston).miR-7/TGF-β2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Xiaoxi Lv1,Chang Liu1,2,Shanshan Liu1,Yunxuan Li1,Wanyu Wang1,Ke Li3,Fang Hua1,Bing Cui1,Xiaowei Zhang1,Jiaojiao Yu1,Jinmei Yu1,Zhuo Wei Hu1(Immunology and Cancer Pharmacology Group,State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College;Drug Clinical Trial Institution,Children's Hospital,Capital Institute of Pediatrics;Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences & Peking Union Medical College).The cell cycle inhibitor P21 promotes the development of pulmonary fibrosis by suppressing lung alveolar regeneration[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Guoyou Xie1,Xu-Nian Wu1,Yuyi Ling1,Yalan Rui1,Deyan Wu1,Jiawang Zhou1,Jiexin Li1,Shuibin Lin2,Qin Peng3,Zigang Li3,Hongsheng Wang1,3,Hai-Bin Luo1,4(School of Pharmaceutical Sciences,Sun Yat-sen University;Center for Translational Medicine,the First Affiliated Hospital,Sun Yat-sen University;Institute of Systems and Physical Biology,Shenzhen Bay Laboratory;Key Laboratory of Tropical Biological Resources of Ministry of Education,School of Life and Pharmaceutical Sciences,Hainan University).A novel inhibitor of N~6-methyladenosine demethylase FTO induces m RNA methylation and shows anti-cancer activities[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Mallory Little1,Moumita Dutta1,Hao Li2,Adam Matson3,Xiaojian Shi4,Gabby Mascarinas1,Bruk Molla1,Kris Weigel1,Haiwei Gu4,Sridhar Mani2,Julia Yue Cui1(Department of Environmental and Occupational Health Sciences,University of Washington;Department of Medicine,Molecular Pharmacology and Genetics,Albert Einstein College of Medicine;University of Connecticut;Arizona Metabolomics Laboratory,College of Health Solutions,Arizona State University).Understanding the physiological functions of the host xenobiotic-sensing nuclear receptors PXR and CAR on the gut microbiome using genetically modified mice[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Min Liao1,Ruiqing Chen1,Yang Yang1,Hanqing He1,Liqian Xu1,Yuxuan Jiang1,Zhenxing Guo2,Wei He1,Hong Jiang3,Jianwei Wang1(School of Pharmaceutical Sciences,Tsinghua University;Department of Hematology/Oncology,First Hospital of Tsinghua University;Kidney Disease Center,the First Affiliated Hospital,College of Medicine,Zhejiang University).Aging-elevated inflammation promotes DNMT3A R878H-driven clonal hematopoiesis[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Qiufen Zhang1,2,Yingyi Chen1,Duan Ni1,Zhimin Huang1,Jiacheng Wei1,Li Feng2,Jun-Cheng Su1,Yingqing Wei1,Shaobo Ning1,Xiuyan Yang1,Mingzhu Zhao1,Yuran Qiu2,Kun Song2,Zhengtian Yu3,Jianrong Xu4,Xinyi Li2,Houwen Lin1,Shaoyong Lu1,Jian Zhang1,2,5(State Key Laboratory of Oncogenes and Related Genes,Department of Pharmacy,Renji Hospital,Shanghai Jiao Tong University School of Medicine;Medicinal Chemistry and Bioinformatics Center,Shanghai Jiao Tong University School of Medicine;Nutshell Therapeutics;Academy of Integrative Medicine,Shanghai University of Traditional Chinese Medicine;School of Pharmaceutical Sciences,Zhengzhou University).Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Ming Ji1,2,Dongjie Wang3,Songwen Lin1,Chunyang Wang3,Ling Li2,Zhihui Zhang3,Jing Jin1,2,Deyu Wu1,Yi Dong1,Heng Xu1,Duo Lu1,Xiaoguang Chen1,3(State Key Laboratory of Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College;Beijing Key Laboratory of Non-Clinical Drug Metabolism and PK/PD Study,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College;Beijing Key Laboratory of New Drug Mechanisms and Pharmacological Evaluation Study,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College).A novel PI3K inhibitor XH30 suppresses orthotopic glioblastoma and brain metastasis in mice models[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Zhifan Mao1,Wenwen Liu1,Yunyuan Huang1,Tianyue Sun1,Keting Bao1,Jiali Feng1,Alexey Moskalev2,Zelan Hu1,Jian Li1,3,4(State Key Laboratory of Bioreactor Engineering,Frontiers Science Center for Materiobiology and Dynamic Chemistry,Shanghai Key Laboratory of New Drug Design,East China University of Science and Technology;Laboratory of Geroprotective and Radioprotective Technologies,Institute of Biology,Komi Science Centre,Ural Branch,Russian Academy of Sciences;Yunnan Key Laboratory of Screening and Research on Anti-pathogenic Plant Resources from West Yunnan,College of Pharmacy,Dali University;Clinical Medicine Scientific and Technical Innovation Center,Shanghai Tenth People's Hospital,Tongji University School of Medicine).Anti-aging effects of chlorpropamide depend on mitochondrial complex-Ⅱ and the production of mitochondrial reactive oxygen species[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Leilei Fu1,Wenke Jin1,Jiahui Zhang2,3,Lingjuan Zhu2,3,Jia Lu4,Yongqi Zhen1,Lan Zhang1,Liang Ouyang2,Bo Liu2,Haiyang Yu4(Sichuan Engineering Research Center for Biomimetic Synthesis of Natural Drugs,School of Life Science and Engineering,Southwest Jiaotong University;State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University;College of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University;State Key Laboratory of Component-based Chinese Medicine,Tianjin University of Traditional Chinese Medicine).Repurposing non-oncology small-molecule drugs to improve cancer therapy:Current situation and future directions[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Lijun Shao1,2,3,Yan Chen4,Shikai Zhang5,Zhihui Zhang5,Yongbing Cao5,Dehua Yang1,2,3,Ming-Wei Wang1,2,3,4,6(The National Center for Drug Screening and CAS Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences(CAS);School of Life Science and Technology,Shanghai Tech University;University of Chinese Academy of Sciences;School of Pharmacy,Fudan University;Shanghai TCM-Integrated Hospital,Shanghai University of Traditional Chinese Medicine;Department of Pharmacology,School of Basic Medical Sciences,Fudan University).Modulating effects of RAMPs on signaling profiles of the glucagon receptor family[J].Acta Pharmaceutica Sinica B,2022,第2期
  • Hong Chen1,Lijun Sun1,Lu Feng1,Michael Mulholland2,Weizhen Zhang1,2,Yue Yin1(Department of Physiology and Pathophysiology,School of Basic Medical Sciences,Key Laboratory of Molecular Cardiovascular Science,Ministry of Education,Peking University;Department of Surgery,University of Michigan Medical Center).Peptidoglycan inhibits beigeing of adipose tissue[J].Acta Pharmaceutica Sinica B,2022,第2期
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