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期刊文章列表

  • Keliang Chen1,Tao Wang2,Yong Li1,Jun Wu1,Cheng-Xiao Zhao1,Sheng Liu1,Fengrun Sun2,Yehong Fang2,Jiahuan Hu1,Jinping Hu1,Chong-Jing Zhang1,Haibo Yu1,Chao Ma2,Shi-Shan Yu1(State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College;Institute of Basic Medical Sciences,Neuroscience Center,Chinese Academy of Medical Sciences,Department of Human Anatomy,Histology and Embryology,School of Basic Medicine,Peking Union Medical College).Rhodojaponin Ⅵ indirectly targets Cav2.2 channels via N-ethylmaleimide-sensitive fusion protein to alleviate neuropathic pain[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Xueqin Huang,Bingbing Sheng,Hemi Tian,Qiuxia Chen,Yingqi Yang,Brian Bui2,Jiang Pi3,Huaihong Cai3,Shanze Chen,Jianglin Zhang,Wei Chen2,Haibo Zhou,Pinghua Sun(The Second Clinical Medical College (Shenzhen People’s Hospital),College of Pharmacy,Jinan University;Department of Physics,the University of Texas at Arlington;Department of Chemistry,Jinan University).Real-time SERS monitoring anticancer drug release along with SERS/MR imaging for pH-sensitive chemo-phototherapy[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Qunjie Bi1,Xu Song2,Yangyang Zhao1,Xueyi Hu1,Huan Yang1,Rongrong Jin1,Yu Nie1(National Engineering Research Center for Biomaterials,College of Biomedical Engineering,Sichuan University;NMPA Key Laboratory for Quality Research and Control of Tissue Regenerative Biomaterial & Institute of Regulatory Science for Medical Devices & NMPA Research Base of Regulatory Science for Medical Devices,Sichuan University).Mucus-penetrating nonviral gene vaccine processed in the epithelium for inducing advanced vaginal mucosal immune responses[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Xin Jin1,2,3,Shuai Wang1,2,Limin Zhao1,2,3,Wenjuan Huang1,2,Yinxiang Zhang1,2,Christophe Pannecouque4,Erik De Clercq4,Ge Meng1,2,Huri Piao3,Fener Chen1,2,3(Engineering Center of Catalysis and Synthesis for Chiral Molecules,Department of Chemistry,Fudan University;Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs;Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules,Ministry of Education,College of Pharmacy,Yanbian University;Rega Institute for Medical Research,KU Leuven).Development of fluorine-substituted NH2-biphenyl-diarylpyrimidines as highly potent non-nucleoside reverse transcriptase inhibitors:Boosting the safety and metabolic stability[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Mengyao Hao1,Rong Fu1,Jun Tai,Zhenhuan Tian3,Xia Yuan4,Yang Chen5,Mingjin Wang1,Huimin Jiang1,Ming Ji1,Fangfang Lai1,Nina Xue1,Liping Bai6,Yizhun Zhu6,Xiaoxi Lv1,Xiaoguang Chen1,Jing Jin1(State Key Laboratory of Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences,Peking Union Medical College;Department of Otolaryngology,Head and Neck Surgery,Children’s Hospital Capital Institute of Pediatrics;Department of Thoracic Surgery,Peking Union Medical College Hospital,Peking Union Medical College;State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University;Department of Pharmacology,School of Pharmaceutical,Guangzhou University of Chinese Medicine;State Key Laboratory of Quality Research in Chinese Medicine,Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology).S1PR1 serves as a viable drug target against pulmonary fibrosis by increasing the integrity of the endothelial barrier of the lung[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Zheng Zhou,Keying Li,Yongchao Chu,Chao Li,Tongyu Zhang,Peixin Liu,Tao Sun,Chen Jiang(Department of Pharmaceutics,School of Pharmacy,Fudan University,Key Laboratory of Smart Drug Delivery,Ministry of Education,State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science).ROS-removing nano-medicine for navigating inflammatory microenvironment to enhance anti-epileptic therapy[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Sae-Bom Yoon1,2,Hyowon Hong1,Hee-Jong Lim1,Ji Hye Choi1,Yoon Pyo Choi3,Seong Wook Seo3,Hyuk Woo Lee3,Chong Hak Chae1,Woo-Kyu Park1,Hyun Young Kim1,Daeyoung Jeong1,Tran Quang De1,Chang-Seon Myung2,Heeyeong Cho1(Therapeutics & Biotechnology Division,Korea Research Institute of Chemical Technology;Department of Pharmacology,Chungnam National University College of Pharmacy;Future Medicine Co.Ltd.Rm616 LH-Business Growth Center).A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Xiaoli Wei1,Fan Yin2,3,Miaomiao Wu1,3,Qianqian Xie3,4,Xueqin Zhao3,4,Cheng Zhu1,Ruiqian Xie3,4,Chongqing Chen3,4,Menghua Liu3,4,Xueying Wang1,Ruixue Ren1,Guijie Kang3,4,Chenwen Zhu1,Jingjing Cong3,4,Hua Wang1,4,Xuefu Wang3,4(Department of Oncology,the First Affiliated Hospital of Anhui Medical University;Department of Pharmacy,Huainan First People's Hospital,the First Affiliated Hospital of Anhui University of Science and Technology;School of Pharmacy,Anhui Medical University;Inflammation and Immune Mediated Diseases Laboratory of Anhui Province,Anhui Medical University).G protein-coupled receptor 35 attenuates nonalcoholic steatohepatitis by reprogramming cholesterol homeostasis in hepatocytes[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Ling-Ling Wu1,2,3,Qinxin Zhao1,2,3,Qinghua Wang1,Qingyang Zhang1,Feiya Yang2,3,Bo Zheng4,Hai-Yu Hu1,Nianzeng Xing2,3,5(State Key Laboratory of Bioactive Substances and Function of Natural Medicine,Institute of Materia Medica,Peking Union Medical College and Chinese Academy of Medical Sciences;Department of Urology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Molecular Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Pathology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Urology,Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital,Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University).Membrane dual-targeting probes:A promising strategy for fluorescence-guided prostate cancer surgery and lymph node metastases detection[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Shiyang Shen,Teng Li,Jinyi Fan,Quanlin Shao,He Dong,Xiao Xu,Ran Mo(State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases,Center of Advanced Pharmaceuticals and Biomaterials,School of Life Science and Technology,China Pharmaceutical University).Lipid-polymer hybrid nanoparticle with cell-distinct drug release for treatment of stemness-derived resistant tumor[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Xingcai Zhang1,Luo Hai2,Yibo Gao2,3,4,5,Guocan Yu6,Yingli Sun3,7,8(School of Engineering and Applied Sciences,Harvard University;Central Laboratory,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Thoracic Surgery,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Molecular Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Laboratory of Translational Medicine,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology,Department of Chemistry,Tsinghua University;University of Chinese Academy of Sciences;CAS Key Laboratory of Genome Sciences and Information,Beijing Institute of Genomics,Chinese Academy of Sciences/China National Center for Bioinformation).Lipid nanomaterials-based RNA therapy and cancer treatment[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Juanjuan Feng1,2,Zhengke Lian1,Xinting Xia1,Yue Lu1,Kewen Hu3,Yunpeng Zhang1,Yanan Liu1,Longmiao Hu1,Kun Yuan1,Zhenliang Sun2,Xiufeng Pang1(Shanghai Key Laboratory of Regulatory Biology,School of Life Sciences,East China Normal University;Joint Center for Translational Medicine,Southern Medical University Affiliated Fengxian Hospital;Cancer Institute,Fudan University Shanghai Cancer Center,Department of Oncology,Shanghai Medical College,Fudan University).Targeting metabolic vulnerability in mitochondria conquers MEK inhibitor resistance in KRAS-mutant lung cancer[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Jiang Wu1,Wenfeng Gou2,Zhiyun Wang3,Huajie Chang3,Deguan Li2,Wenbin Hou2,Changxiao Liu4(Department of Pharmaceutical Engineering,School of Chemical Engineering and Technology,Tianjin University;Institute of Radiation Medicine,Chinese Academy of Medical Sciences;School of Chinese Materia Medica,Tianjin University of Traditional Chinese Medicine;Research Center for New Drug Evaluation,the State Laboratory of Drug Delivery Technology and Pharmacokinetics,Tianjin Institute of Pharmaceutical Research).Discovery of the radio-protecting effect of Ecliptae Herba,its constituents and targeting p53-mediated apoptosis in vitro and in vivo[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Tengjie Yu1,Zhihao Zhou1,Shijia Liu2,Changjian Li1,Zhi-Wei Zhang3,Yong Zhang3,Wei Jin1,Keanqi Liu1,Shuying Mao1,Lei Zhu2,Lin Xie1,Guangji Wang1,Yan Liang1(Key Lab of Drug Metabolism & Pharmacokinetics,State Key Laboratory of Natural Medicines,China Pharmaceutical University;Affliated Hospital of Nanjing University of Chinese Medicine;College of Chemical & Pharmaceutical Engineering,Hebei University of Science & Technology).The role of phosphatidylcholine 34:1 in the occurrence,development and treatment of ulcerative colitis[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Lu Zhang1,Xiaolei Zhou2,Bowen Liu3,Xuhe Shi1,Xianmeng Li1,Feifei Xu1,Xueli Fu1,Xue Wang1,Kai Ye1,Tianzhi Jin1,Huimin Sun1,Qianqian Li1,Weiying Zhang1,Lihong Ye1(State Key Laboratory of Medicinal Chemical Biology,Tianjin Key Laboratory of Protein Sciences,Department of Biochemistry and Molecular Biology,College of Life Sciences,Nankai University;College of Food Science & Biology,Hebei University of Science and Technology;Henan Key Laboratory of Immunology and Targeted Drugs,School of Laboratory Medicine,Xinxiang Medical University).HBXIP blocks myosin-ⅡA assembly by phosphorylating and interacting with NMHC-ⅡA in breast cancer metastasis[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Ning Shao1,Xueyang Ma2,Ying-Ying Zhang1,Donghui Yang2,Ming Ma2,Gong-Li Tang1,3(State Key Laboratory of Bioorganic and Natural Products Chemistry,Center for Excellence in Molecular Synthesis,Shanghai Institute of Organic Chemistry,University of Chinese Academy of Sciences,Chinese Academy of Sciences;State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University;School of Chemistry and Materials Science Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences).Dihydrofolate reductase-like protein inactivates hemiaminal pharmacophore for self-resistance in safracin biosynthesis[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Geni Ye,Maohua Huang,Yong Li,Jie Ouyang,Minfeng Chen,Qing Weng,Xiaobo Li,Huhu Zeng,Pei Long,Zepei Fan,Junqiang Yin,Wencai Ye,Dongmei Zhang(College of Pharmacy;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research;Integrated Chinese and Western Medicine Postdoctoral Research Station;Department of Musculoskeletal Oncology).Author correction to“The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway”[Acta Pharm Sin B 12(2022)1288–1304][J].药学学报(英文版),2023,第3期
  • Huaqing Zheng,Xiaolong Li,Xin Zeng,Chengcui Huang,Mingming Ma,Xiaofei Lv,Yajuan Zhang,Lu Sun,Guanlei Wang,Yanhua Du,Yongyuan Guan(Department of Pharmacology).Author correction to“TMEM16A inhibits angiotensin Ⅱ-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner”[Acta Pharm Sin B 11(12)(2021)3994–4007][J].药学学报(英文版),2023,第3期
  • (Editoral Office of Acta Pharmaceutica Sinica).Information for Authors[J].Acta Pharmaceutica Sinica B,2023,第3期
  • Chen Fu1,2,Lifeng Yu1,Yuxi Miao1,2,3,Xinli Liu4,Zhaojin Yu1,2,Minjie Wei1,2,3(Department of Pharmacology,School of Pharmacy,China Medical University;Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation,China Medical University;Liaoning Medical Diagnosis and Treatment Center;Department of Digestive Oncology,Cancer Hospital of China Medical University,Liaoning Cancer Hospital&Institute).Peptide-drug conjugates(PDCs):a novel trend of research and development on targeted therapy, hype or hope?[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yeuan Ting Lee,Yi Jer Tan,Chern Ein Oon(Institute for Research in Molecular Medicine (INFORMM),Universiti Sains Malaysia).Benzimidazole and its derivatives as cancer therapeutics:The potential role from traditional to precision medicine[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yujun Zhou1,Jingshu Tang1,Jiaqi Lan1,Yong Zhang1,Hongyue Wang1,Qiuyu Chen1,Yuying Kang1,Yang Sun2,Xinhong Feng3,Lei Wu1,Hongtao Jin4,5,Shizhong Chen2,Ying Peng1(State Key Laboratory of Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences&Peking Union Medical College;Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University;Department of Neurology,Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University;New Drug Safety Evaluation Center,Institute of Materia Medica,Chinese Academy of Medical Sciences&Peking Union Medical College;NMPA Key Laboratory for Safety Research and Evaluation of Innovative Drug).Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Haowen Xu1,2,Jiahao Chen1,Pan Chen1,Weifeng Li1,Jingjing Shao1,2,Shanshan Hong1,Yi Wang1,Lingfeng Chen2,Wu Luo1,3,Guang Liang1,2(Chemical Biology Research Center,School of Pharmaceutical Sciences,Wenzhou Medical University;School of Pharmaceutical Sciences,Hangzhou Medical College;Medical Research Center,the First Affiliated Hospital of Wenzhou Medical University).Costunolide covalently targets NACHT domain of NLRP3 to inhibit inflammasome activation and alleviate NLRP3-driven inflammatory diseases[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Ze Mi1,Qing Yao1,2,3,Yan Qi2,Jinhai Zheng4,Jiahao Liu1,Zhenguo Liu1,Hongpei Tan1,Xiaoqian Ma1,Wenhu Zhou1,5,6,Pengfei Rong1,6(Department of Radiology,The Third Xiangya Hospital,Central South University;Department of Pathology,Shihezi University School of Medicine and the First Affiliated Hospital to Shihezi University School of Medicine;Department of Pathology,Cangzhou Central Hospital&the Affiliated to Hebei Medical University;School of Biomedical Sciences,Hunan University;Xiangya School of Pharmaceutical Sciences,Central South University;Key Laboratory of Biological Nanotechnology of National Health Commission).Salmonella-mediated blood-brain barrier penetration, tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Jianjun Cheng1,2,3,Haitian Zhao1,4,5,Bin Li6,Hua Zhang2,Qianyu Zhao1,2,Shiyao Fu1,2,Ying Han1,2,Weihong Lu1,4,5,Jiahua Shi3,Xin Yang1,2,4,5(School of Medicine and Health,Harbin Institute of Technology;School of Chemistry and Chemical Engineering,Harbin Institute of Technology;Key Laboratory of Natural Medicine and Immune-Engineering of Henan Province,Henan University;Chongqing Research Institute,Harbin Institute of Technology;National and Local Joint Engineering Laboratory for Synthesis,Transformation and Separation of Extreme Environmental Nutrients;Academician Workstation,Jiangxi University of Chinese Medicine).Photosensitive pro-drug nanoassemblies harboring a chemotherapeutic dormancy function potentiates cancer immunotherapy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Qianhua Feng1,2,Yutong Hao1,Shuaiqi Yang1,Xiaomin Yuan1,Jing Chen1,Yuying Mei1,Lanlan Liu3,Junbiao Chang2,4,Zhenzhong Zhang1,2,Lei Wang1,2(School of Pharmaceutical Sciences,Zhengzhou University;Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases;Department of Pharmacy,The Third Affiliated Hospital of Zhengzhou University;College of Chemistry,Zhengzhou University).A metabolic intervention strategy to break evolutionary adaptability of tumor for reinforced immunotherapy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Shuang Cui,Huijian Hu,An Chen,Ming Cui,Xiaojie Pan,Pengfei Zhang,Guangji Wang,Hong Wang,Haiping Hao(State Key Laboratory of Natural Medicines,Key Laboratory of Drug Metabolism&Pharmacokinetics,China Pharmaceutical University).SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Dayuan Wang1,Xiao Gu1,Xinyi Ma1,Jun Chen2,Qizhi Zhang2,Zhihua Yu1,Juan Li1,Meng Hu1,Xiaofang Tan1,Yuyun Tang1,Jianrong Xu1,3,Minjun Xu2,Qingxiang Song1,Huahua Song1,Gan Jiang1,Zaiming Tang4,Xiaoling Gao1,Hongzhuan Chen1,3(Department of Pharmacology and Chemical Biology,State Key Laboratory of Oncogenes and Related Genes,Shanghai Universities Collaborative Innovation Center for Translational Medicine,Shanghai Jiao Tong University School of Medicine;Key Laboratory of Smart Drug Delivery,Ministry of Education,School of Pharmacy,Fudan University;Shanghai Frontiers Science Center of TCM Chemical Biology,Institute of Interdisciplinary Integrative Medicine Research,Shanghai University of Traditional Chinese Medicine;Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education,Shanghai Jiao Tong University School of Medicine).Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Nazi Song1,Hongjiao Xu1,Shuohan Wu1,Suijia Luo2,Jingyao Xu1,Qian Zhao1,Rui Wang3,4,Xianxing Jiang1(School of Pharmaceutical Sciences,Sun Yat-sen University;Shenzhen Turier Biotech.Co.,Ltd.;State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences&Peking Union Medical College;School of Life Sciences,Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences&Research Unit of Peptide Science,Lanzhou University).Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs-EBP interaction recover NAFLD through enhancing mitochondrial function in mice[J].Acta Pharmaceutica Sinica B,2023,第2期
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