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Meng Chen1,2,Zhengyan Guo1,3,Jinyuan Sun1,2,Wei Tang1,2,Min Wang1,4,Yue Tang1,Pengwei Li1,Bian Wu1,2,Yihua Chen1,2(State Key Laboratory of Microbial Resources&CAS Key Laboratory of Microbial Physiological and Metabolic Engineering,Institute of Microbiology,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Laboratory of Microbial Metabolic Engineering,Institute of Medicinal Biotechnology,Chinese Academy of Medical Science&Peking Union Medical College;School of Biotechnology and Health Sciences,Wuyi University).Insights into the biosynthesis of septacidin L-heptosamine moiety unveils a VOC family sugar epimerase[J].Acta Pharmaceutica Sinica B,2023,第2期
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Yang Liu1,Ting Liu2,Yuanzhang Zhou2,Wenjie Li2,Min Wang3,Nanshan Song2,Wenbin Zhang4,Jingwei Jiang5,Shengtao Yuan5,Jianhua Ding2,Gang Hu2,1,Ming Lu2(Department of Pharmacology,School of Medicine and Holistic Integrative Medicine,Nanjing University of Chinese Medicine;Jiangsu Key Laboratory of Neurodegeneration,Department of Pharmacology,Nanjing Medical University;Department of Geriatrics,Affiliated Brain Hospital of Nanjing Medical University;Department of Neurosurgery,Affiliated Brain Hospital of Nanjing Medical University;Jiangsu Key Laboratory of Drug Screening,China Pharmaceutical University).Impeding the combination of astrocytic ASCT2 and NLRP3 by talniflumate alleviates neuroinflammation in experimental models of Parkinson’s disease[J].Acta Pharmaceutica Sinica B,2023,第2期
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Xiaolin Zhang1,2,Xueyan Zhen1,2,Yixuan Yang1,2,Quan Feng1,2,Wanqing Yuan1,2,Xiaoyu Xie1,2(School of Pharmacy,Health Science Center,Xi'an Jiaotong University;Shaanxi Engineering Research Center of Cardiovascular Drugs Screening&Analysis).Precise assembly of inside-out cell membrane camouflaged nanoparticles via bioorthogonal reactions for improving drug leads capturing[J].Acta Pharmaceutica Sinica B,2023,第2期
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Lingyan Wang1,2,Guiyang Xia1,Huan Xia1,Xiaohong Wei1,Yanan Wang2,Sheng Lin1(Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing,Dongzhimen Hospital,Beijing University of Chinese Medicine;State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College).(+)/(-)-Yanhusamides A-C, three pairs of unprecedented benzylisoquinoline-pyrrole hetero-dimeric alkaloid enantiomers from Corydalis yanhusuo[J].Acta Pharmaceutica Sinica B,2023,第2期
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Tao He,Mingxing Hu,Shunyao Zhu,Meiling Shen,Xiaorong Kou,Xiuqi Liang,Lu Li,Xinchao Li,Miaomiao Zhang,Qinjie Wu,Changyang Gong(State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University).A tactical nanomissile mobilizing antitumor immunity enables neoadjuvant chemo-immunotherapy to minimize postsurgical tumor metastasis and recurrence[J].Acta Pharmaceutica Sinica B,2023,第2期
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Yin Feng1,2,Yefan Han1,2,Anni Hu1,2,Yi Qu1,2,Yili Hu3,Hao Wu1,Xinzhi Wang1,2,Li He4(College of Pharmacy,Nanjing University of Chinese Medicine;China Jiangsu Key Laboratory of Research and Development in Marine Bio-resource Pharmaceutics;Experiment Center for Science and Technology,Nanjing University of Chinese Medicine;Department of Hematology,Zhongnan Hospital of Wuhan University).Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia[J].Acta Pharmaceutica Sinica B,2023,第2期
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Zhifu Xie1,Mei Zhang1,Qian Song1,2,Long Cheng1,2,Xinwen Zhang1,Gaolei Song1,2,Xinyu Sun1,Min Gu1,Chendong Zhou1,Yangming Zhang1,3,Kexin Zhu1,Jianpeng Yin4,Xiaoyan Chen1,Jingya Li1,2,Fajun Nan1,2,4(State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Burgeon Therapeutics Co.,Ltd.;Drug Discovery Shandong Laboratory,Bohai Rim Advanced Research Institute for Drug Discovery).Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia[J].Acta Pharmaceutica Sinica B,2023,第2期
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Jian Lu,Xuyang Shang,Bingyi Yao,Dongyi Sun,Jie Liu,Yuanjin Zhang,He Wang,Jingru Shi,Huaqing Chen,Tieliu Shi,Mingyao Liu,Xin Wang(Changning Maternity and Infant Health Hospital and School of Life Sciences,Shanghai Key Laboratory of Regulatory Biology,East China Normal University).The role of CYP1A1/2 in cholesterol ester accumulation provides a new perspective for the treatment of hypercholesterolemia[J].Acta Pharmaceutica Sinica B,2023,第2期
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Lujing Geng1,Tong Lu2,Huaqing Jing1,Yue Zhou1,Xiaoyang Liang1,Jiao Li2,Nan Li1(Tianjin Key Laboratory of Drug Delivery&High-Efficiency,School of Pharmaceutical Science and Technology,Tianjin University;School of Precision Instruments and Optoelectronics Engineering,Tianjin University).Iron-based and BRD4-downregulated strategy for amplified ferroptosis based on pH-sensitive/NIR-Ⅱ-boosted nano-matchbox[J].Acta Pharmaceutica Sinica B,2023,第2期
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Jizhou Tan1,2,Ting Liu3,4,Wenzhe Fan1,Jialiang Wei1,Bowen Zhu1,Yafang Liu2,Lingwei Liu1,Xiaokai Zhang1,Songling Chen2,Haibiao Lin3,4,Yuanqing Zhang5,Jiaping Li1(Department of Interventional Oncology,the First Affiliated Hospital,Sun Yat-sen University;Department of Stomatology,the First Affiliated Hospital,Sun Yat-sen University;Department of Laboratory Medicine,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Provincial Hospital of Traditional,Chinese Medicine;Second Clinical Medical College,Guangzhou University of Chinese Medicine;School of Pharmaceutical Sciences,Sun Yat-sen University).Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+cells elimination in hepatocellular carcinoma[J].Acta Pharmaceutica Sinica B,2023,第2期
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Di Zhao1,2,Jing Zhang1,Lingyuan Zhang1,Qingnan Wu1,2,3,Yan Wang1,2,3,Weimin Zhang1,2,4,Yuanfan Xiao1,Jie Chen1,2,3,Qimin Zhan1,2,3,4(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Laboratory of Molecular Oncology,Peking University Cancer Hospital&Institute;Research Unit of Molecular Cancer Research,Chinese Academy of Medical Sciences;Peking University International Cancer Institute;Shenzhen Bay Laboratory).PAFR/Stat3 axis maintains the symbiotic ecosystem between tumor and stroma to facilitate tumor malignancy[J].Acta Pharmaceutica Sinica B,2023,第2期
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Zhengjie Lu1,2,Yu Guo1,3,Dan Xu1,3,Hao Xiao2,3,Yongguo Dai1,Kexin Liu1,Liaobin Chen2,3,Hui Wang1,3(Department of Pharmacology,Wuhan University School of Basic Medical Science;Department of Orthopedic Surgery,Zhongnan Hospital of Wuhan University;Hubei Provincial Key Laboratory of Developmentally Originated Disorder).Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy[J].Acta Pharmaceutica Sinica B,2023,第2期
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Huaan Li1,2,Fei Peng3,Xiaohui Yan4,Chun Mao5,Xing Ma6,Daniela A.Wilson7,Qiang He8,Yingfeng Tu1,2(Department of Pharmacy,Zhujiang Hospital,Southern Medical University;School of Pharmaceutical Science,Guangdong Provincial Key Laboratory of New Drug Screening,Southern Medical University;School of Materials Science and Engineering,Sun Yat-Sen University;State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics&Centre for Molecular Imaging and Translational Medicine,School of Public Health,Xiamen University;National and Local Joint Engineering Research Center of Biomedical Functional Materials,School of Chemistry and Materials Science,Nanjing Normal University;Sauvage Laboratory for Smart Materials,School of Materials Science and Engineering,Harbin Institute of Technology(Shenzhen);Institute for Molecules and Materials,Radboud University;Key Laboratory of Microsystems and Microstructures Manufacturing(Ministry of Education),School of Medicine and Health,Harbin Institute of Technology).Medical micro-and nanomotors in the body[J].Acta Pharmaceutica Sinica B,2023,第2期
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Dan Wang1,2,Bochuan Deng1,2,Lu Cheng1,2,Jieru Li1,2,Jiao Zhang1,2,Xiang Zhang1,2,Xiaomin Guo1,2,Tiantian Yan1,2,Xin Yue1,2,Yingying An1,2,Bangzhi Zhang1,2,Wenle Yang1,2,Junqiu Xie1,2,Rui Wang1,2(Institute of Materia Medica and Research Unit of Peptide Science,Chinese Academy of Medical Sciences,Peking Union Medical College;Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences,Lanzhou University).A novel and low-toxic peptide DR3penA alleviates pulmonary fibrosis by regulating the MAPK/miR-23b-5p/AQP5 signaling axis[J].Acta Pharmaceutica Sinica B,2023,第2期
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Yijun Chen,Kaiming Li,Mengying Jiao,Yingshuang Huang,Zihao Zhang,Lingjing Xue,Caoyun Ju,Can Zhang(State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases,Center of Advanced Pharmaceuticals and Biomaterials,China Pharmaceutical University).Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy[J].Acta Pharmaceutica Sinica B,2023,第2期
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Wenhui Wang1,Pengyu Liu2,Yalin Zhang3,Li Yan3,Michael X.Zhu4,Jin Wang3,Ye Yu3(Department of Pharmacology,School of Pharmacy,China Pharmaceutical University;Department of Medical Genetics and Developmental Biology,School of Medicine,the Key Laboratory of Developmental Genes and Human Diseases,Ministry of Education,Southeast University;School of Basic Medicine and Clinical Pharmacy and State Key Laboratory of Natural Medicines,China Pharmaceutical University;Department of Integrative Biology and Pharmacology,McGovern Medical School,the University of Texas Health Science Center at Houston).Expression and functions of transient receptor potential channels in liver diseases[J].Acta Pharmaceutica Sinica B,2023,第2期
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Changpei Gan1,Jing Wang1,Alejandra Martínez-Chávez1,2,Michel Hillebrand2,Niels de Vries2,Joke Beukers2,Els Wagenaar1,Yaogeng Wang1,Maria C.Lebre1,Hilde Rosing2,Sjoerd Klarenbeek3,Rahmen Bin Ali4,Colin Pritchard4,Ivo Huijbers4,5,Jos H.Beijnen1,2,6,Alfred H.Schinkel1(Division of Pharmacology,the Netherlands Cancer Institute;Department of Pharmacy&Pharmacology,the Netherlands Cancer Institute;Experimental Animal Pathology Facility,the Netherlands Cancer Institute;Mouse Clinic for Cancer and Aging(MCCA)Transgenic Facility,the Netherlands Cancer Institute;Faculty of Science,Swammerdam Institute for Life Sciences,University of Amsterdam;Division of Pharmacoepidemiology and Clinical Pharmacology,Utrecht Institute for Pharmaceutical Sciences,Utrecht University).Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism[J].Acta Pharmaceutica Sinica B,2023,第2期
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Siyuan Tang1,Miguel Garzon Sanz1,Oliver Smith1,Andreas Kr?mer2,3,4,5,Daniel Egbase,Paul W.Caton,Stefan Knapp2,3,4,5,Sam Butterworth1(Division of Pharmacy and Optometry,School of Health Sciences,Manchester Academic Health Sciences Centre,University of Manchester;Structural Genomics Consortium(SGC);Buchmann Institute for Life Sciences(BMLS);Institut für Pharmazeutische Chemie,Goethe University;Frankfurt Cancer Institute(FCI);Department of Diabetes,School of Cardiovascular and Metabolic Medicine&Sciences,Faculty of Life Sciences&Medicine,King’s College London).Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators[J].Acta Pharmaceutica Sinica B,2023,第2期
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Shuyi Wang,Jun Tao,Huaguo Chen,Machender R.Kandadi,Mingming Sun,Haixia Xu,Gary D.Lopaschuk,Yan Lu,Junmeng Zheng,Hu Peng,Jun Ren(Department of Emergency;Shanghai University School of Medicine;University of Wyoming College of Health Sciences;Department of Cardiovascular Surgery;Medprime Health Services LLC;Department of Cardiology;Department of Cardiology;Cardiovascular Research Centre;Key Laboratory of Metabolism and Molecular Medicine;Department of Laboratory Medicine and Pathology).Author correction to‘Ablation of Akt2 and AMPKα2 rescues high fat diet-induced obesity and hepatic steatosis through Parkin-mediated mitophagy’[Acta Pharmaceutica Sinica B 11(2021)3508-3526][J].药学学报(英文版),2023,第2期
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Ziru Yu,Dewen Kong,Yu Liang,Xiaoyue Zhao,Guanhua Du(State Key Laboratory of Bioactive Substances and Functions of Natural Medicines).Author correction to‘Protective effects of VMY-2-95 on corticosterone-induced injuries in mice and cellular models’[Acta Pharmaceutica Sinica B 11(2021)1903-1913][J].药学学报(英文版),2023,第2期
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Mingming Sun1,Leilei Li2,Yujia Niu3,Yingzhi Wang1,Qi Yan1,Fei Xie1,Yaya Qiao1,Jiaqi Song1,Huanran Sun1,Zhen Li2,Sizhen Lai4,Hongkai Chang1,Han Zhang1,Jiyan Wang1,Chenxin Yang4,Huifang Zhao4,Junzhen Tan4,Yanping Li5,Shuangping Liu6,Bin Lu7,8,Min Liu9,Guangyao Kong10,Yujun Zhao11,Chunze Zhang12,Shu-Hai Lin3,Cheng Luo11,Shuai Zhang4,Changliang Shan1,11(State Key Laboratory of Medicinal Chemical Biology,College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research,Nankai University;Biomedical Translational Research Institute,Jinan University;State Key Laboratory of Cellular Stress Biology,Innovation Center for Cell Signaling Network,School of Life Sciences,Xiamen University;School of Integrative Medicine,Tianjin University of Traditional Chinese Medicine;Department of Pathology and Institute of Precision Medicine,Jining Medical University;Department of Pathology,Medical School,Dalian University;Department of Biochemistry and Molecular Biology,School of Basic Medical Sciences,Hengyang Medical School,University of South China;School of Laboratory Medicine and Life Sciences,Wenzhou Medical University;Institute of Biomedical Sciences,Shandong Provincial Key Laboratory of Animal Resistance Biology,Collaborative Innovation Center of Cell Biology in Universities of Shandong,College of Life Sciences,Shandong Normal University;National Local Joint Engineering Research Center of Biodiagnostics and Biotherapy,the Second Affiliated Hospital of Xi’an Jiaotong University;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;Department of Colorectal Surgery,Tianjin Union Medical Center,Nankai University).PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism[J].Acta Pharmaceutica Sinica B,2023,第1期
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Panat Yanpiset1,2,3,Chayodom Maneechote1,3,Sirawit Sriwichaiin1,2,3,Natthaphat Siri-Angkul1,2,3,Siriporn C.Chattipakorn1,3,4,Nipon Chattipakorn1,2,3(Cardiac Electrophysiology Research and Training Center,Faculty of Medicine,Chiang Mai University;Cardiac Electrophysiology Unit,Department of Physiology,Faculty of Medicine,Chiang Mai University;Center of Excellence in Cardiac Electrophysiology Research,Chiang Mai University;Department of Oral Biology and Diagnostic Sciences,Faculty of Dentistry,Chiang Mai University).Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury:Cumulative evidence for future cardioprotective strategies[J].Acta Pharmaceutica Sinica B,2023,第1期
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Yizhen Wang1,Qijun Lv1,You Chen2,Langtao Xu2,Miao Feng2,Zhiyong Xiong1,Jiajun Li1,Jie Ren3,Jie Liu2,Bo Liu1(Department of General Surgery,the Third Affiliated Hospital of Sun Yat-sen University;School of Biomedical Engineering,Sun Yat-sen University;Department of Ultrasound,the Third Affiliated Hospital of Sun Yat-sen University).Bilayer hydrogel dressing with lysozymeenhanced photothermal therapy for biofilm eradication and accelerated chronic wound repair[J].Acta Pharmaceutica Sinica B,2023,第1期
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Yangyang Duan,Wenyu Du,Zhijun Song,Ridao Chen,Kebo Xie,Jimei Liu,Dawei Chen,Jungui Dai(State Key Laboratory of Bioactive Substance and Function of Natural Medicines,CAMS Key Laboratory of Enzyme and Biocatalysis of Natural Drugs,NHC Key Laboratory of Biosynthesis of Natural Products,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College).Functional characterization of a cycloartenol synthase and four glycosyltransferases in the biosynthesis of cycloastragenol-type astragalosides from Astragalus membranaceus[J].Acta Pharmaceutica Sinica B,2023,第1期
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Hangyi Wu1,Pei Yang1,Aiqin Li1,Xin Jin1,2,Zhenhai Zhang3,4,HuiXia Lv1(Department of Pharmaceutics,China Pharmaceutical University;The Affiliated Suqian First People's Hospital of Nanjing Medical University;Jiangsu Province Academy of Traditional Chinese Medicine;Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine).Chlorella sp.-ameliorated undesirable microenvironment promotes diabetic wound healing[J].Acta Pharmaceutica Sinica B,2023,第1期
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Tao Zhang1,Guowei Gu1,Guodong Liu2,Jinhua Su,Zhilai Zhan4,Jianyuan Zhao1,Jinxiu Qian4,Guowei Cai1,Shan Cen1,Dewu Zhang1,Liyan Yu1(Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Microbial Technology,National Glycoengineering Research Center,Shandong University;The Third Medical Center,The General Hospital of People’s Liberation Army;National Resource Center for Chinese Materia Medica,China Academy of Chinese Medical Sciences).Late-stage cascade of oxidation reactions during the biosynthesis of oxalicine B in Penicillium oxalicum[J].Acta Pharmaceutica Sinica B,2023,第1期
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