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Jiafan Yang1,2,Zhenbin Zhou1,2,Yingying Chen1,Yongxiang Song1,2,Jianhua Ju1,2(CAS Key Laboratory of Tropical Marine Bio-resources and Ecology,RNAM Center for Marine Microbiology,Guangdong Key Laboratory of Marine Materia Medica,South China Sea Institute of Oceanology,Chinese Academy of Sciences;University of Chinese Academy of Sciences).Characterization of the depsidone gene cluster reveals etherification, decarboxylation and multiple halogenations as tailoring steps in depsidone assembly[J].Acta Pharmaceutica Sinica B,2023,第9期
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Junjie Yang1,Yue Pan1,Xiaoshan Zeng1,Shuwen Liu1,Zhipeng Chen1,Kui Cheng1,2(Guangdong Provincial Key Laboratory of New Drug Screening and NMPA Key Laboratory for Research and Evaluation of Drug Metabolism,School of Pharmaceutical Sciences,Southern Medical University;Department of Musculoskeletal Oncology,the Third Affiliated Hospital of Southern Medical University).Discovery of novel aporphine alkaloid derivative as potent TLR2 antagonist reversing macrophage polarization and neutrophil infiltration against acute inflammation[J].Acta Pharmaceutica Sinica B,2023,第9期
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Mei Lu1,2,Haonan Xing2,3,Wanxuan Shao1,Pengfei Wu1,Yuchuan Fan1,Huining He4,Stefan Barth5,Aiping Zheng3,Xing-Jie Liang2,Yuanyu Huang1(Advanced Research Institute of Multidisciplinary Science,School of Life Science,School of Medical Technology,Key Laboratory of Molecular Medicine and Biotherapy,Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering,Beijing Institute of Technology;Chinese Academy of Sciences (CAS) Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,CAS Center for Excellence in Nanoscience,National Center for Nanoscience and Technology of China;State Key Laboratory of Toxicology and Medical Countermeasures,Beijing Institute of Pharmacology and Toxicology;Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics,School of Pharmacy,Tianjin Medical University;South African Research Chair in Cancer Biotechnology,Institute of Infectious Disease and Molecular Medicine(IDM),Department of Integrative Biomedical Sciences,Faculty of Health Sciences,University of Cape Town).Antitumor synergism between PAK4 silencing and immunogenic phototherapy of engineered extracellular vesicles[J].Acta Pharmaceutica Sinica B,2023,第9期
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Hao Tian1,2,Juanfeng Ou1,Yong Wang2,Jia Sun1,Junbin Gao1,Yicheng Ye1,Ruotian Zhang1,Bin Chen1,Fei Wang1,Weichang Huang1,Huaan Li1,2,Lu Liu1,Chuxiao Shao,Zhili Xu4,Fei Peng5,Yingfeng Tu1,2(NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening,School of Pharmaceutical Sciences,Southern Medical University;Department of Pharmacy,Zhujiang Hospital,Southern Medical University;Key Laboratory of Joint Diagnosis and Treatment of Chronic Liver Disease and Liver Cancer of Lishui,Central Laboratory of Lishui People’s Hospital,The Sixth Affiliated Hospital of Wenzhou Medical University;Department of Ultrasound,Institute of Ultrasound in Musculoskeletal Sports Medicine,Guangdong Second Provincial General Hospital;School of Materials Science and Engineering,Sun Yat-Sen University).Bladder microenvironment actuated proteomotors with ammonia amplification for enhanced cancer treatment[J].Acta Pharmaceutica Sinica B,2023,第9期
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Jiawei Wu,Liyun Xing,Yaxian Zheng,Yinglan Yu,Ruinan Wu,Xi Liu,Lian Li,Yuan Huang(Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province,Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University).Disease-specific protein corona formed in pathological intestine enhances the oral absorption of nanoparticles[J].Acta Pharmaceutica Sinica B,2023,第9期
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Huiwen Liu1,Honglan Wang1,Qiyu Li2,Yiwei Wang1,Ying He3,Xuejing Li3,Chunyan Sun1,Onder Ergonul4,Füsun Can4,Zhiqing Pang3,Bo Zhang1,Yu Hu1(Institute of Hematology,Union Hospital,Tongji Medical College,Huazhong University of Science & Technology;Department of Cardiology,Zhongshan Hospital,Fudan University,Shanghai Institute of Cardiovascular Diseases;School of Pharmacy,Fudan University,Key Laboratory of Smart Drug Delivery,Ministry of Education;Koc University Is Bank Center for Infectious Diseases (KUISCID),Lnfectious Diseases and Clinical Microbiology Department,Ko? University School of Medicine and American Hospital).LPS adsorption and inflammation alleviation by polymyxin B-modified liposomes for atherosclerosis treatment[J].Acta Pharmaceutica Sinica B,2023,第9期
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Hanyu Yang1,2,Mengxiang Su3,Ming Liu2,Yun Sheng2,Liang Zhu2,Lu Yang1,2,Ruijing Mu1,2,Jianjun Zou4,Xiaodong Liu1,2,Li Liu1,2(State Key Laboratory of Natural Medicines,Key Laboratory of Drug Metabolism and Pharmacokinetics,China Pharmaceutical University;Department of Pharmacology,School of Pharmacy,China Pharmaceutical University;Department of Pharmaceutical Analysis,School of Pharmacy,China Pharmaceutical University;Department of Clinical Pharmacology,Nanjing First Hospital,Nanjing Medical University).Hepatic retinaldehyde deficiency is involved in diabetes deterioration by enhancing PCK1-and G6PC-mediated gluconeogenesis[J].Acta Pharmaceutica Sinica B,2023,第9期
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Xin Tang1,2,Chuanxi Wang3,Lei Wang4,5,Feifei Ren2,Runqiao Kuang3,Zhenhua Li1,2,Xue Han3,Yiming Chen2,Guodong Chen3,Xiuqing Wu2,Jie Liu4,Hengwen Yang2,Xingzhong Liu6,Chen Wang4,Hao Gao3,Zhinan Yin1,2(Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment,Zhuhai Institute of Translational Medicine,Zhuhai People's Hospital Affiliated with Jinan University,Jinan University;Biomedical Translational Research Institute,Health Science Center (School of Medicine),Jinan University;Institute of Traditional Chinese Medicine and Natural Products,College of Pharmacy/Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research/International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Ministry of Education (MOE) of China,Jinan University;Department of Respirology,Capital Medical University;Department of Respiratory and Critical Care Medicine,the Second Affiliated Hospital of Xi'an Jiaotong University (Xibei Hospital);State Key Laboratory of Mycology,Institute of Microbiology,Chinese Academy of Sciences).Aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activity[J].Acta Pharmaceutica Sinica B,2023,第9期
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Xudong Xing,Mengru Sun,Zifan Guo,Yongjuan Zhao,Yuru Cai,Ping Zhou,Huiying Wang,Wen Gao,Ping Li,Hua Yang(State Key Laboratory of Natural Medicines,School of Traditional Chinese Pharmacy,China Pharmaceutical University).Functional annotation map of natural compounds in traditional Chinese medicines library:TCMs with myocardial protection as a case[J].Acta Pharmaceutica Sinica B,2023,第9期
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Zhicheng Liu1,2,Zhuolei Han3,Xin Jin4,Jusung An5,Jaewon Kim5,Wenting Chen6,Jong Seung Kim5,Ji Zheng1,2,Jun Deng3(Department of Urology,Xinqiao Hospital,Third Military Medical University (Army Medical University);Department of Urology,Urological Surgery Research Institute,Southwest Hospital,Third Military Medical University (Army Medical University);Institute of Burn Research,Southwest Hospital,State Key Lab of Trauma,Burn and Combined Injury,Chongqing Key Laboratory for Disease Proteomics,Third Military Medical University (Army Medical University);Tianjin Key Laboratory of Composite and Functional Materials,School of Materials Science and Engineering,Tianjin University;Department of Chemistry,Korea University;Department of Rheumatology and Clinical Immunology,Army Medical Center,Third Military Medical University (Army Medical University)).Regulating the microenvironment with nanomaterials:Potential strategies to ameliorate COVID-19[J].Acta Pharmaceutica Sinica B,2023,第9期
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Huaqing Zheng,Xiaolong Li,Xin Zeng,Chengcui Huang,Mingming Ma,Xiaofei Lv,Yajuan Zhang,Lu Sun,Guanlei Wang,Yanhua Du,Yongyuan Guan(Department of Pharmacology).Author correction to‘TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner'[Acta Pharmaceutica Sinica B 11(2021)3994-4007][J].药学学报(英文版),2023,第9期
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Li-qian Ci,Zhi-gang Huang,Yu Liu,Zhe-peng Liu,Gang Wei,Wei-yue Lu(School of Medical Instrument and Food Engineering;Department of Pharmaceutics).Author correction to‘Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties:Preparation,characterization and application in vaginal drug delivery system'[Acta Pharm Sin B 7(2017)593-602][J].药学学报(英文版),2023,第9期
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Lijuan Xue1,Keanqi Liu1,Caixia Yan2,Junling Dun3,Yexin Xu1,Linlin Wu1,Huizhu Yang1,Huafang Liu1,Lin Xie1,Guangji Wang1,Yan Liang1(Key Lab of Drug Metabolism & Pharmacokinetics,State Key Laboratory of Natural Medicines,China Pharmaceutical University;Zhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research,Department of Clinical Pharmacy,the First Affiliated Hospital,Zhejiang University School of Medicine;Analytical Applications Center,Shimadzu (China) Co.Ltd.).Schisandra lignans ameliorate nonalcoholic steatohepatitis by regulating aberrant metabolism of phosphatidylethanolamines[J].Acta Pharmaceutica Sinica B,2023,第8期
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Huan Zhang,Jie Yang,Rongze Sun,Songren Han,Zhaogang Yang,Lesheng Teng(School of Life Sciences,Jilin University).Microfluidics for nano-drug delivery systems:From fundamentals to industrialization[J].Acta Pharmaceutica Sinica B,2023,第8期
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Chao Liu1,2,Wei Liu1,3,Yanhong Liu1,2,Hongxia Duan1,2,Liqing Chen1,2,Xintong Zhang1,2,Mingji Jin1,2,Minhu Cui4,Xiuquan Quan4,Libin Pan1,Jiachun Hu1,Zhonggao Gao1,2,Yan Wang1,Wei Huang1,2(State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College;Beijing Key Laboratory of Drug Delivery Technology and Novel Formulations,Department of Pharmaceutics,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Histology and Embryology,Chongqing Key Laboratory of Neurobiology,Brain and Intelligence Research Key Laboratory of Chongqing Education Commission,Third Military Medical University;Department of Gastroenterology,Yanbian University Hospital).Versatile flexible micelles integrating mucosal penetration and intestinal targeting for effectively oral delivery of paclitaxel[J].Acta Pharmaceutica Sinica B,2023,第8期
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Jo?o Moreira1,Mariana Machado2,Mónica Dias-Teixeira1,3,Ricardo Ferraz2,4,Cristina Delerue-Matos1,Clara Grosso1(REQUIMTE/LAQV,Instituto Superior de Engenharia do Porto,Instituto Politécnico do Porto;Ciências Químicas e das Biomoléculas/CISA,Escola Superior de Saúde—Instituto Politécnico do Porto;NICiTeS—Núcleo de Investiga??o em Ciências e Tecnologias da Saúde,Escola Superior de Saúde Ribeiro Sanches;REQUIMTE/LAQV,Departamento de Química e Bioquímica Faculdade de Ciências,Universidade do Porto).The neuroprotective effect of traditional Chinese medicinal plants——A critical review[J].Acta Pharmaceutica Sinica B,2023,第8期
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Xin Yue1,2,Tingyu Liu1,Xuecen Wang2,Weijian Wu3,Gesi Wen4,Yang Yi2,Jiaxin Wu3,Ziyang Wang5,Weixiang Zhan6,Ruirui Wu3,Yuan Meng1,Zhirui Cao7,Liyuan Le8,Wenyan Qiu8,Xiaoyue Zhang2,Zhenyu Li1,Yong Chen2,Guohui Wan3,Xianzhang Bu3,9,Zhenwei Peng2,Ran-yi Liu1(State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center;Department of Radiation Oncology,the First Affiliated Hospital,Sun Yat-sen University;School of Pharmaceutical Sciences,Sun Yat-sen University;Department of Clinical Research,Guangzhou Institute of Respiratory Health,the First Affiliated Hospital of Guangzhou Medical University;Department of Gastrointestinal Surgery,the First Affiliated Hospital,Sun Yat-sen University;Department of Oncology,the Sixth Affiliated Hospital,Sun Yat-sen University;Department of Traditional Chinese Medicine,the First Affiliated Hospital,Sun Yat-sen University;Zhongshan School of Medicine,Sun Yat-sen University;Laboratory of Chemical Oncogenomics,Guangdong Provincial Key Laboratory of Chemical Genomics,Peking University Shenzhen Graduate School).Pharmacological inhibition of BAP1 recruits HERC2 to competitively dissociate BRCA1-BARD1, suppresses DNA repair and sensitizes CRC to radiotherapy[J].Acta Pharmaceutica Sinica B,2023,第8期
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Aixue Li1,2,3,Dan Li2,3,Yongwei Gu2,3,Rongmei Liu1,2,3,Xiaomeng Tang2,3,Yunan Zhao2,3,Fu Qi1,2,3,Jifu Wei4,5,6,Jiyong Liu1,2,3,7(College of Pharmacy,Shandong University of Traditional Chinese Medicine;Department of Pharmacy,Fudan University Shanghai Cancer Center;Department of Oncology,Shanghai Medical College,Fudan University;Department of Pharmacy,Jiangsu Cancer Hospital;Jiangsu Institute of Cancer Research;The Affiliated Cancer Hospital of Nanjing Medical University;Department of Pharmacy,Shanghai Proton and Heavy Ion Center).Plant-derived nanovesicles:Further exploration of biomedical function and application potential[J].Acta Pharmaceutica Sinica B,2023,第8期
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Yao Yang1,Zimu Li1,Ping Huang1,Jiachan Lin1,Jinyuan Li2,Kexin Shi1,Jiahui Lin1,Jingwen Hu1,Zhuoxian Zhao1,Yongkang Yu1,3,Hongzhong Chen1,Xiaowei Zeng1,Lin Mei3(Institute of Pharmaceutics,School of Pharmaceutical Sciences(Shenzhen),Sun Yat-sen University;State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yatsen University Cancer Center;Tianjin Key Laboratory of Biomedical Materials,Key Laboratory of Biomaterials and Nanotechnology for Cancer Immunotherapy,Institute of Biomedical Engineering,Chinese Academy of Medical Sciences,Peking Union Medical College).Rapidly separating dissolving microneedles with sustained-release colchicine and stabilized uricase for simplified long-term gout management[J].Acta Pharmaceutica Sinica B,2023,第8期
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Yingying Hou1,2,Min Chen1,2,Yuan Bian1,2,Xi Zheng1,2,Rongsheng Tong1,2,Xun Sun3(Department of Pharmacy,Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital,School of Medicine,University of Electronic Science and Technology of China;Personalized Drug Therapy Key Laboratory of Sichuan Province,School of Medicine,University of Electronic Science and Technology of China;Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province,Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University).Advanced subunit vaccine delivery technologies:From vaccine cascade obstacles to design strategies[J].Acta Pharmaceutica Sinica B,2023,第8期
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Dianyang Li1,Wenying Yu2,Maode Lai1,3(School of Basic Medicine and Clinical Pharmacy,China Pharmaceutical University;State Key Laboratory of Natural Medicines,China Pharmaceutical University;Department of Pathology,Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy,Chinese Academy of Medical Science(2019RU042),Key Laboratory of Disease Proteomics of Zhejiang Province,Zhejiang University School of Medicine).Towards understandings of serine/arginine-rich splicing factors[J].Acta Pharmaceutica Sinica B,2023,第8期
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Ke Yang1,2,Lei Xu1,2,Ying Xu1,3,Qian Shen1,2,4,Tao Qin1,3,5,Yunfang Yu1,3,5,Yan Nie1,5,Herui Yao1,3,5,Xiaoding Xu1,2(Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation,Medical Research Center,Sun Yat-sen Memorial Hospital,Sun Yat-sen University;Nanhai Translational Innovation Center of Precision Immunology,Sun Yat-sen Memorial Hospital;Department of Oncology,Sun Yat-sen Memorial Hospital,Sun Yat-sen University;Department of Clinical Pharmacology,the Second Affiliated Hospital,University of South China;Breast Tumor Center,Sun Yat-sen Memorial Hospital,Sun Yat-sen University).Nanoparticles(NPs)-mediated lncBCMA silencing to promote eEF1A1 ubiquitination and suppress breast cancer growth and metastasis[J].Acta Pharmaceutica Sinica B,2023,第8期
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Haowei Liu1,Qiuming Huang1,Yunqi Fan1,Bo Li1,Xuemei Liu1,2,Changhua Hu1,2(College of Pharmaceutical Sciences,Southwest University;NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances,Chongqing Institute for Food and Drug Control).Dissecting the novel abilities of aripiprazole:The generation of anti-colorectal cancer effects by targeting Gαq via HTR2B[J].Acta Pharmaceutica Sinica B,2023,第8期
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Bo-Yun Han1,Zi-Long Wang1,Junhao Li2,Qing Jin1,3,Hao-Tian Wang1,Kuan Chen1,Yang Yi1,Hans ?gren2,Xue Qiao1,Min Ye1,4(State Key Laboratory of Natural and Biomimetic Drugs,School of Pharmaceutical Sciences,Peking University;Department of Physics and Astronomy,Uppsala University;College of Life Science,Anhui Agricultural University;Peking University-Yunnan Baiyao International Medical Research Center).A highly selective C-rhamnosyltransferase from Viola tricolor and insights into its mechanisms[J].Acta Pharmaceutica Sinica B,2023,第8期
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Fan Tong,Haili Hu,Yanyan Xu,Yang Zhou,Rou Xie,Ting Lei,Yufan Du,Wenqin Yang,Siqin He,Yuan Huang,Tao Gong,Huile Gao(Key Laboratory of Drug Targeting and Drug Delivery Systems,West China School of Pharmacy,Sichuan University).Hollow copper sulfide nanoparticles carrying ISRIB for the sensitized photothermal therapy of breast cancer and brain metastases through inhibiting stress granule formation and reprogramming tumor-associated macrophages[J].Acta Pharmaceutica Sinica B,2023,第8期
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Huanhuan Pang1,2,Zeping Hu1(School of Pharmaceutical Sciences,Tsinghua-Peking Center for Life Sciences,Beijing Frontier Research Center for Biological Structure,Tsinghua University;Artemisinin Research Center,Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences).Metabolomics in drug research and development:The recent advances in technologies and applications[J].Acta Pharmaceutica Sinica B,2023,第8期
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Ying Lu1,2,Fan Shen1,2,Wen-Qiang He1,2,An-Qi Li1,2,Ming-Hua Li3,Xiao-Li Feng3,Yong-Tang Zheng1,2,Wei Pang1,2(Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province,KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases,Center for Biosafety Mega-Science,Kunming Institute of Zoology,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Kunming National High-level Biosafety Research Center for Non-human Primates,Center for Biosafety Mega-Science,Kunming Institute of Zoology,Chinese Academy of Sciences).HR121 targeting HR2 domain in S2 subunit of spike protein can serve as a broad-spectrum SARS-CoV-2 inhibitor via intranasal administration[J].Acta Pharmaceutica Sinica B,2023,第8期
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Qingqing Xiao1,Xiaotong Li1,Chang Liu1,Yuxin Jiang1,Yonglong He1,Wanting Zhang1,Helena S.Azevedo2,Wei Wu3,Yuanzheng Xia4,Wei He1(School of Pharmacy,China Pharmaceutical University;School of Engineering and Materials Science,Institute of Bioengineering,Queen Mary University of London;School of Pharmacy,Fudan University;Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines,School of Traditional Chinese Pharmacy,China Pharmaceutical University).Improving cancer immunotherapy via co-delivering checkpoint blockade and thrombospondin-1 downregulator[J].Acta Pharmaceutica Sinica B,2023,第8期
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Shiwen Song1,Dong Sun1,Hong Wang1,2,Jinliang Wang3,Huijing Yan3,Xuan Zhao3,John Paul Fawcett1,Xin Xu1,Deqi Cai1,4,Jingkai Gu1,4,5(Research Center for Drug Metabolism,School of Life Sciences,Jilin University;Center for Food and Drug Inspection of NMPA;Jen Kem Technology Co.Ltd.;State Key Laboratory of Supramolecular Structure and Materials,College of Chemistry,Jilin University;Beijing Institute of Drug Metabolism).Full-profile pharmacokinetics, anticancer activity and toxicity of an extended release trivalent PEGylated irinotecan prodrug[J].Acta Pharmaceutica Sinica B,2023,第8期
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Mingli Duan1,2,3,4,5,Yurui Jia1,2,3,4,5,Lifang Huo1,2,3,4,5,6,Yiting Gao1,2,3,4,5,Jia Wang1,2,3,4,5,Wei Zhang6,2,3,Zhanfeng Jia1,2,3,4,5(Department of Pharmacology,Hebei Medical University;Center of Innovative Drug Research and Evaluation,Institute of Medical Science and Health,Hebei Medical University;The Key Laboratory of Neural and Vascular Biology,Ministry of Education;The Key Laboratory of New Drug Pharmacology and Toxicology;The Hebei Collaboration Innovation Center for Mechanism,Diagnosis and Treatment of Neurological and Psychiatric Disease;Department of Pharmacology,Institute of Chinese Integrative Medicine,Hebei Medical University).Potentiation of PIEZO2 mechanically-activated currents in sensory neurons mediates vincristine-induced mechanical hypersensitivity[J].Acta Pharmaceutica Sinica B,2023,第8期
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