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Zhiming Zhangy,Chenlu Huangy,Li Zhang,Qing Guo,Yu Qin,Fan Fan,Boxuan Li,Bao Xiao,Dunwan Zhu,Linhua Zhang(Tianjin Key Laboratory of Biomedical Materials,Key Laboratory of Biomaterials and Nanotechnology for Cancer Immunotherapy,Institute of Biomedical Engineering,Chinese Academy of Medical Sciences & Peking Union Medical College,Tianjin 300192,China).pH-sensitive and bubble-generating mesoporous silica-based nanoparticles for enhanced tumor combination therapy[J].药学学报(英文版),2021,第2期
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Xiaohua Liu,Yu Zhang,Yalei Li,Juan Wang,Huaqian Ding,Wenjing Huang,Chunyong Ding,Hongchun Liu,Wenfu Tan,Ao Zhang(CAS Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica (SIMM),Chinese Academy of Sciences,Shanghai 201203,China;School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200240,China;University of Chinese Academy of Sciences,Beijing 100049,China;Department of Pharmacology,School of Pharmacy,Fudan University,Shanghai 201203,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica (SIMM),Chinese Academy of Sciences,Shanghai 201203,China;CAS Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica (SIMM),Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;CAS Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica (SIMM),Chinese Academy of Sciences,Shanghai 201203,China;School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200240,China;CAS Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica (SIMM),Chinese Academy of Sciences,Shanghai 201203,China;School of Pharmacy,Shanghai Jiao Tong University,Shanghai 200240,China;School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China;University of Chinese Academy of Sciences,Beijing 100049,China;State Key Laboratory of Esophageal Cancer Prevention and Treatment,Ministry of Education of China,Zhengzhou University,Zhengzhou 450001,China).Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma[J].药学学报(英文版),2021,第2期
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Yunkai Yang,Xiaohan Guo,Bo Hu,Peng He,Xiaowu Jiang,Zuohuan Wang,Huaxing Zhu,Lina Hu,Minghua Yu,Meiqing Feng(Shanghai Engineering Research Center of ImmunoTherapeutics,School of Pharmacy,Fudan University,Shanghai 201203,China;Shanghai Novoprotein Biotechnology Co.,Ltd.,Shanghai 201203,China;Medical School of Yichun University,Yichun 336000,China;Clinical Research Center,2nd Affiliated Hospital,Medical College of Zhejiang University,Hangzhou 310009,China;Department of Oncology,Shanghai Pudong Hospital,Fudan University Pudong Medicine Center Shanghai 201399,China).Generated SecPen_NY-ESO-1_ubiquitin-pulsed dendritic cell cancer vaccine elicits stronger and specific T cell immune responses[J].药学学报(英文版),2021,第2期
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Dominik Bakalarz,Marcin Surmiak,Xiaoxiao Yang,Dagmara Wójcik,Edyta Korbut,ZbigniewSliwowski,Grzegorz Ginter,Grzegorz Buszewicz,Tomasz Brzozowski,Jakub Cieszkowski,Urszula Głowacka,Katarzyna Magierowska,Zhixiang Pan,Binghe Wang,Marcin Magierowski(Department of Physiology,Jagiellonian University Medical College,Cracow 31-531,Poland;Department of Forensic Toxicology,Institute of Forensic Research,Cracow 31-033,Poland;Department of Physiology,Jagiellonian University Medical College,Cracow 31-531,Poland;Department of Internal Medicine,Jagiellonian University Medical College,Cracow 31-531,Poland;Department of Chemistry and Center for Diagnostics and Therapeutics,Georgia State University,Atlanta,GA 30303,USA;Department of Physiology,Jagiellonian University Medical College,Cracow 31-531,Poland;Department of Forensic Medicine,Medical University of Lublin,Lublin 20-093,Poland).Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage[J].药学学报(英文版),2021,第2期
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Xinran Cai,Ye Feng,Meishu Xu,Chaohui Yu,Wen Xie(Center for Pharmacogenetics and Department of Pharmaceutical Sciences,University of Pittsburgh,Pittsburgh,PA 15261,USA;Center for Pharmacogenetics and Department of Pharmaceutical Sciences,University of Pittsburgh,Pittsburgh,PA 15261,USA;Department of Endocrinology and Metabolic Disease,the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China;Department of Gastroenterology,the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China;Center for Pharmacogenetics and Department of Pharmaceutical Sciences,University of Pittsburgh,Pittsburgh,PA 15261,USA;Department of Pharmacology and Chemical Biology,University of Pittsburgh,Pittsburgh,PA 15261,USA).Gadd45b is required in part for the anti-obesity effect of constitutive androstane receptor(CAR)[J].药学学报(英文版),2021,第2期
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Xiaofei Chen,Yunlong Wu,Chun Chen,Yanqiu Gu,Chunyan Zhu,Suping Wang,Jiayun Chen,Lei Zhang,Lei Lv,Guoqing Zhang,Yongfang Yuan,Yifeng Chai,Mingshe Zhu,Caisheng Wu(School of Pharmacy,Naval Medical University,Shanghai 200433,China;Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cellular Stress Biology,School of Pharmaceutical Sciences,Xiamen University,Xiamen 361102,China;Department of Pharmacy,Shanghai Ninth People's Hospital,Shanghai Jiao Tong University,Shanghai 201999,China;Department of Pharmacy,Shanghai Eastern Hepatobiliary Surgery Hospital,Naval Medical University,Shanghai 200438,China;MassDefect Technologies,Princeton,NJ 08540,USA).Identifying potential anti-COVID-19 pharmacological components of traditional Chinese medicine Lianhuaqingwen capsule based on human exposure and ACE2 biochromatography screening[J].药学学报(英文版),2021,第1期
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Jingwei Bian,Zijian Li(Department of Cardiology and Institute of Vascular Medicine,Peking University Third Hospital;Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides,Ministry of Health;Key Laboratory of Molecular Cardiovascular Sciences,Ministry of Education;Beijing Key Laboratory of Cardiovascular Receptors Research,Beijing 100191,China;Department of Pharmacy,Peking University Third Hospital,Beijing 100191,China).Angiotensin-converting enzyme 2(ACE2):SARS-CoV-2 receptor and RAS modulator[J].药学学报(英文版),2021,第1期
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Zhendong Song,Meijing Wang,Yang Ge,Xue-Ping Chen,Ziyang Xu,Yang Sun,Xiao-Feng Xiong(Guangdong Key Laboratory of Chiral Molecule and Drug Discovery,School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510006,China;State Key Laboratory of Pharmaceutical Biotechnology,Department of Biotechnology and Pharmaceutical Sciences,School of Life Sciences,Nanjing University,Nanjing 210023,China).Tyrosine phosphatase SHP2 inhibitors in tumortargeted therapies[J].药学学报(英文版),2021,第1期
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Hao Zengy,Lingling Wangy,Jiawei Zhang,Ting Pan,Yinghua Yu,Jingxia Lu,Ping Zhou,Hua Yang,Ping Li(State Key Laboratory of Natural Medicines,School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 210009,China).Activated PKB/GSK-3β synergizes with PKC-δ signaling in attenuating myocardial ischemia/reperfusion injury via potentiation of NRF2 activity:Therapeutic efficacy of dihydrotanshinone-I[J].药学学报(英文版),2021,第1期
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Zhibin Yan,Dan Wang,Chunmei An,Hongjiao Xu,Qian Zhao,Ying Shi,Nazi Song,Bochuan Deng,Xiaomin Guo,Jing Rao,Lu Cheng,Bangzhi Zhang,Lingyun Mou,Wenle Yang,Xianxing Jiang,Junqiu Xie(Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences &Research Unit of Peptide Science,Chinese Academy of Medical Sciences,2019RU066,Lanzhou University,Lanzhou 730000,China;School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510006,China).The antimicrobial peptide YD attenuates inflammation via miR-155 targeting CASP12 during liver fibrosis[J].药学学报(英文版),2021,第1期
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Xiaojie Chen,Jiafeng Zou,Ke Zhang,Jingjing Zhu,Yue Zhang,Zhihong Zhu,Hongyue Zheng,Fanzhu Li,Ji-Gang Piao(College of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Libraries of Zhejiang Chinese Medical University,Zhejiang Chinese Medical University,Hangzhou 310053,China).Photothermal/matrix metalloproteinase-2 dual-responsive gelatin nanoparticles for breast cancer treatment[J].药学学报(英文版),2021,第1期
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Jinyang Li,Jiasheng Lu,Haiyan Guo,Jianfen Zhou,Songli Wang,Kuan Jiang,Zhilan Chai,Shengyu Yao,Xiaoyi Wang,Linwei Lu,Cao Xie,Yi Chen,Weiyue Lu(Department of Pharmaceutics,School of Pharmacy,Fudan University & Key Laboratory of Smart Drug Delivery(Fudan University),Ministry of Education and PLA,Shanghai 201203,China;The Institutes of Integrative Medicine of Fudan University,Shanghai 200041,China;Chinese Academy of Sciences Shanghai Institute of Materia Medica,Shanghai 201203,China;State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Institutes of Brain Science,Fudan University,Shanghai 200032,China;Minhang Branch,Zhongshan Hospital and Institute of Fudan-Minghang Academic Health System,Minghang Hospital,Fudan University,Shanghai 201199,China).A pentapeptide enabled AL3810 liposome-based glioma-targeted therapy with immune opsonic effect attenuated[J].药学学报(英文版),2021,第1期
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Jiezhou Ye,Bo Zeng,Meiyan Zhong,Hongchun Li,Lihui Xu,Junxiang Shu,Yaofeng Wang,Fan Yang,Chunsu Zhong,Xunjia Ye,Xianhui He,Dongyun Ouyang(Department of Immunobiology,College of Life Science and Technology,Jinan University,Guangzhou 510632,China;Wuzhongpei Memorial Hospital of Shunde,Foshan 528300,China;Department of Cell Biology,College of Life Science and Technology,Jinan University,Guangzhou 510632,China).Scutellarin inhibits caspase-11 activation and pyroptosis in macrophages via regulating PKA signaling[J].药学学报(英文版),2021,第1期
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Yilan Shen,Wei Chen,Lei Han,Qi Bian,Jiajun Fan,Zhonglian Cao,Xin Jin,Tao Ding,Zongshu Xian,Zhiyong Guo,Wei Zhang,Dianwen Ju,Xiaobin Mei(Department of Nephrology,Changhai Hospital,Second Military Medical University,Shanghai 200433,China;Department of Biological Medicines,Fudan University School of Pharmacy,Shanghai 201203,China;Department of Ophthalmology,Stanford University School of Medicine,Palo Alto,CA 94304,USA;Department of Nephrology,Shanghai Yangpu Hospital of TCM,Shanghai 200090,China).VEGF-B antibody and interleukin-22 fusion protein ameliorates diabetic nephropathy through inhibiting lipid accumulation and inflammatory responses[J].药学学报(英文版),2021,第1期
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Kai Yuan,Xiao Wang,Haojie Dong,Wenjian Min,Haiping Hao,Peng Yang(State Key Laboratory of Natural Medicines and Jiangsu Key Laboratory of Drug Design and Optimization,China Pharmaceutical University,Nanjing 210009,China;Department of Medicinal Chemistry,School of Pharmacy,China Pharmaceutical University,Nanjing 210009,China).Selective inhibition of CDK4/6:A safe and effective strategy for developing anticancer drugs[J].药学学报(英文版),2021,第1期
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Hongxia Duan,Yanhong Liu,Zhonggao Gao,Wei Huang(State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Department of Pharmaceutics,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China;Beijing Key Laboratory of Drug Delivery Technology and Novel Formulations,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China).Recent advances in drug delivery systems for targeting cancer stem cells[J].药学学报(英文版),2021,第1期
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Yanying Zhou,Xiaomei Fan,Tingying Jiao,Wenzhou Li,Panpan Chen,Yiming Jiang,Jiahong Sun,Yixin Chen,Pan Chen,Lihuan Guan,Yajie Wen,Min Huang,Huichang Bi(School of Pharmaceutical Sciences,Sun Yat-sen University,Guangzhou 510006,China;Shenzhen Baoan Women's and Children's Hospital,Jinan University,Shenzhen 518102,China;Department of Pharmacy,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou 510080,China).SIRT6 as a key event linking P53 and NRF2 counteracts APAP-induced hepatotoxicity through inhibiting oxidative stress and promoting hepatocyte proliferation[J].药学学报(英文版),2021,第1期
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Xiaopan Gao,Bo Qin,Pu Chen,Kaixiang Zhu,Pengjiao Hou,Justyna Aleksandra Wojdyla,Meitian Wang,Sheng Cui(NHC Key Laboratory of Systems Biology of Pathogens,Institute of Pathogen Biology,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;The Swiss Light Source (SLS) at the Paul Scherrer Institut,Villigen 5232,Switzerland).Crystal structure of SARS-CoV-2 papain-like protease[J].药学学报(英文版),2021,第1期
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Bing Zhao,Xinhui Zhang,Tingting Yu,Ying Liu,Xiaoling Zhang,Yongfang Yao,Xuejian Feng,Hongmin Liu,Dequan Yu,Liying Ma,Shangshang Qin(State Key Laboratory of Esophageal Cancer Prevention and Treament,Key Laboratory of Technology of Drug Preparation (Zhengzhou University),Ministry of Education of China,Key Laboratory of Henan Province for Drug Quality and Evaluation,Institute of Pharmaceutical Research and School of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China;State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050,China).Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1(NDM-1)inhibitors against NDM-1 producing clinical isolates[J].药学学报(英文版),2021,第1期
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Jie Cheny,Yan Wangy,Di Zhao,Lingyuan Zhang,Weimin Zhang,Jiawen Fan,Jinting Li,Qimin Zhan(Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing),Laboratory of Molecular Oncology,Peking University Cancer Hospital &Institute,Beijing 100142,China).Chrysin serves as a novel inhibitor of DGKα/FAK interaction to suppress the malignancy of esophageal squamous cell carcinoma(ESCC)[J].药学学报(英文版),2021,第1期
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Xiaosa Changy,Dejuan Suny,Danfeng Shiy,Guan Wang,Yanmei Chen,Kai Zhang,Huidan Tan,Jie Liu,Bo Liu,Liang Ouyang(State Key Laboratory of Biotherapy and Cancer Center West China Hospital,Collaborative Innovation Center of Biotherapy,Sichuan University,Chengdu 610041,China).Design,synthesis,and biological evaluation of quinazolin-4(3H)-one derivatives co-targeting poly(ADP-ribose)polymerase-1 and bromodomain containing protein 4 for breast cancer therapy[J].药学学报(英文版),2021,第1期
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Shun Zhang,Yan Zhao,Shuyuan Wang,Min Li,Yue Xu,Jianhua Ran,Xiaoqiang Geng,Jinzhao He,Jia Meng,Guangying Shao,Hong Zhou,Zemei Ge,Guangping Cheng,Runtao Li,Baoxue Yang(Department of Pharmacology,School of Basic Medical Sciences,Peking University,Beijing 100191,China;State Key Laboratory of Natural and Biomimetic Drugs,Peking University,Beijing 100191,China;Key Laboratory of Molecular Cardiovascular Sciences,Ministry of Education,Beijing 100191,China;School of Pharmaceutical Sciences,Peking University,Beijing 100191,China;College of Pharmacy,Inner Mongolia Medical University,Hohhot 010110,China;Department of Anatomy and Neuroscience Center Chongqing Medical University,Chongqing 400016,China;Department of Physiology,Emory University School of Medicine,Atlanta,GA 30322,USA).Discovery of novel diarylamides as orally active diuretics targeting urea transporters[J].药学学报(英文版),2021,第1期
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Bingchen Zhang,Jiali Jiang,Pengyu Wu,Junjie Zou,Jingqing Le,Juanfang Lin,Chao Li,Bangyue Luo,Yongjie Zhang,Rui Huang,Jingwei Shao(Fujian Provincial Key Laboratory of Cancer Metastasis Chemoprevention and Chemotherapy,College of Chemistry,Fuzhou University,Fuzhou 350116,China;Institute of Oceanography,Minjiang University,Fuzhou 350108,China).A smart dual-drug nanosystem based on co-assembly of plant and food-derived natural products for synergistic HCC immunotherapy[J].药学学报(英文版),2021,第1期
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Shuang Zhou,Jinbo Li,Jiang Yu,Liyuan Yang,Xiao Kuang,Zhenjie Wang,Yingli Wang,Hongzhuo Liu,Guimei Lin,Zhonggui He,Dan Liu,Yongjun Wang(Wuya College of Innovation,Shenyang Pharmaceutical University,Shenyang 110016,China;School of Pharmaceutical Science,Shandong University,Jinan 250012,China;Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education,Shenyang Pharmaceutical University,Shenyang 110016,China).A facile and universal method to achieve liposomal remote loading of non-ionizable drugs with outstanding safety profiles and therapeutic effect[J].药学学报(英文版),2021,第1期
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Zeqi Zhou,Xiangbin Wang,Yankai Fu,Xiqing Zhang,Changxiao Liu(Dynamiker Biotechnology Sub-Center Beijing Key Laboratory for Mechanism Study and Precision Diagnosis of Invasive Fungal Diseases,Tianjin 300467,China;Beijing Antai Zhiyuan Technology Co.,Ltd.,Beijing 102206,China;State Key Laboratory of Drug Delivery Technology and Pharmacokinetics,Tanjin Institute of Pharmaceutical Research,Tianjin 300462,China).Letter to the editor:Neutralizing antibodies for the treatment of COVID-19[J].药学学报(英文版),2021,第1期
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