-
Yi-xiao Dong,Shi-feng Chu,Sha-sha Wang,Ya-juan Tian,Wen-bin He,Yu-sheng Du,Zhen-zhen Wang,Xu Yan,Zhao Zhang,Nai-hong Chen(State Key Laboratory of Bioactive Substances and Functions of Natural Medicines;Tianjin University of Traditional Chinese Medicine;Shanxi Key Laboratory of Chinese Medicine Encephalopathy).Rg1 exerts protective effect in CPZ-induced demyelination mouse model via inhibiting CXCL10-mediated glial response[J].中国药理学报(英文版),2022,第3期
-
Xu-xia Li,Peng Zhang,Yang Yang,Jing-jing Wang,Yan-jun Zheng,Ji-liang Tan,Shen-yan Liu,Yong-ming Yan,You-yi Zhang,Yong-xian Cheng,Huang-tian Yang(CAS Key Laboratory of Tissue Microenvironment and Tumor;State Key Laboratory of Phytochemistry and Plant Resources in West China;Department of Cardiology and Institute of Vascular Medicine;NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides;Key Laboratory of Molecular Cardiovascular Science;School of Pharmaceutical Sciences;Department of Cardiology;Institute for Stem Cell and Regeneration).Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway[J].中国药理学报(英文版),2022,第3期
-
Xiao Mo,Cheng-fei Zhang,Ping Xu,Min Ding,Zhi-jie Ma,Qi Sun,Yu Liu,Hong-kai Bi,Xin Guo,Alaa Abdelatty,Chao Hu,Hao-jun Xu,Guo-ren Zhou,Yu-liang Jia,Hong-ping Xia(Sir Run Run Hospital,Nanjing Medical University,Nanjing 211166,China;School of Basic Medical Sciences&State Key Laboratory of Reproductive Medicine&Key Laboratory of Antibody Technique of National Health Commission&Jiangsu Antibody Drug Engineering Research Center,Nanjing Medical University,Nanjing 210092,China;School of Basic Medical Sciences&State Key Laboratory of Reproductive Medicine&Key Laboratory of Antibody Technique of National Health Commission&Jiangsu Antibody Drug Engineering Research Center,Nanjing Medical University,Nanjing 210092,China;Sir Run Run Hospital,Nanjing Medical University,Nanjing 211166,China;Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical University,Nanjing 210092,China;Yijishan Hospital of Wannan Medical College,Wannan Medical College,Wuhu 241002,China;Sir Run Run Hospital,Nanjing Medical University,Nanjing 211166,China;Yijishan Hospital of Wannan Medical College,Wannan Medical College,Wuhu 241002,China;School of Basic Medical Sciences&State Key Laboratory of Reproductive Medicine&Key Laboratory of Antibody Technique of National Health Commission&Jiangsu Antibody Drug Engineering Research Center,Nanjing Medical University,Nanjing 210092,China).KCNN4-mediated Ca2+/MET/AKT axis is promising for targeted therapy of pancreatic ductal adenocarcinoma[J].中国药理学报(英文版),2022,第3期
-
Tae Woo Kim(Department of Preventive Medicine).Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cells[J].中国药理学报(英文版),2022,第3期
-
Lin-lin Chang,Yue-kang Li,Chen-xi Zhao,Chen-ming Zeng,Fu-jing Ge,Jia-min Du,Wen-zhou Zhang,Pei-hua Lu,Qiao-jun He,Hong Zhu,Bo Yang(Zhejiang Province Key Laboratory of Anti-Cancer Drug Research;Department of Pharmacy;Department of Medical Oncology).AKR1C1 connects autophagy and oxidative stress by interacting with SQSTM1 in a catalytic-independent manner[J].中国药理学报(英文版),2022,第3期
-
An Cheng,Yi-fei Wang,Yasuharu Shinoda,Ichiro Kawahata,Tetsunori Yamamoto,Wen-bin Jia,Hanae Yamamoto,Tomohiro Mizobata,Yasushi Kawata,Kohji Fukunaga(Department of Pharmacology;Department of Chemistry and Biotechnology).Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress[J].中国药理学报(英文版),2022,第3期
-
Sun Yang,Li Zijian.The multifunctional adaptor protein HIP-55 couples Smad7 to accelerate TGF-beta type I receptor degradation[J].中国药理学报,2022,第3期
-
Hong Yu,Hong-ying Gao,Hua Guo,Gui-zhen Wang,Yi-qing Yang,Qian Hu,Li-jun Liang,Qun Zhao,Da-wei Xie,Yu Rao,Guang-biao Zhou(School of Chinese Materia Medica;State Key Laboratory of Molecular Oncology;MOE Key Laboratory of Protein Sciences;Hubei University of Medicine).Upregulation of wild-type p53 by small molecule-induced elevation of NQO1 in non-small cell lung cancer cells[J].中国药理学报(英文版),2022,第3期
-
Zan Guiying,Sun Xiang,Wang Yujun,Liu Rui,Wang Chenyao,Du Weijia,Guo Liubin,Chai Jingrui,Li Qinglin,Liu Zhiqiang,Liu Jinggen.Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress[J].中国药理学报,2022,第3期
-
Gui-ying Zan,Xiang Sun,Yu-jun Wang,Rui Liu,Chen-yao Wang,Wei-jia Du,Liu-bin Guo,Jing-rui Chai,Qing-lin Li,Zhi-qiang Liu,Jing-gen Liu(Department of Anesthesiology,Shanghai First Maternity and Infant Hospital,Tongji University School of Medicine,Shanghai 201204,China;Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;Key Laboratory of Xin'an Medicine,Ministry of Education,Anhui Province Key Laboratory of R&D of Chinese Medicine,Anhui University of Chinese Medicine,Hefei 230038,China;Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;Department of Anesthesiology,Shanghai First Maternity and Infant Hospital,Tongji University School of Medicine,Shanghai 201204,China;Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China).Amygdala dynorphin/K opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress[J].中国药理学报(英文版),2022,第3期
-
Cheng An,Wang Yifei,Shinoda Yasuharu,Kawahata Ichiro,Yamamoto Tetsunori,Jia Wenbin,Yamamoto Hanae,Mizobata Tomohiro,Kawata Yasushi,Fukunaga Kohji.Fatty acid-binding protein 7 triggers alpha-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress[J].中国药理学报,2022,第3期
-
Yang Sun,Zi-jian Li(Department of Cardiology and Institute of Vascular Medicine;Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides;Key Laboratory of Molecular Cardiovascular Sciences;Beijing Key Laboratory of Cardiovascular Receptors Research).The multifunctional adaptor protein HIP-55 couples Smad7 to accelerate TGF-β type Ⅰ receptor degradation[J].中国药理学报(英文版),2022,第3期
-
Chang-ling Gu,Hai-xia Zhu,Lan Deng,Xiao-qing Meng,Kai Li,Wei Xu,Le Zhao,Yue-qin Liu,Zhen-ping Zhu,Hao-min Huang(Sunshine Guojian Pharmaceutical(Shanghai)Co.Ltd.).Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition[J].中国药理学报(英文版),2022,第3期
-
Lei Xu,Tian-yu Yang,Yi-wen Zhou,Mei-fei Wu,Jie Shen,Jie-ling Cheng,Qing-xue Liu,Shi-yang Cao,Jian-qing Wang,Lei Zhang(School of Pharmacy;Inflammation and Immune Mediated Diseases Laboratory of Anhui Province;The Key Laboratory of Anti-inflammatory and Immune Medicines;The Fourth Affiliated Hospital of Anhui Medical University).Author Correction:Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis[J].中国药理学报(英文版),2022,第3期
-
Lei Xu,Tian-yu Yang,Yi-wen Zhou,Mei-fei Wu,Jie Shen,Jie-ling Cheng,Qing-xue Liu,Shi-yang Cao,Jian-qing Wang,Lei Zhang(School of Pharmacy;Inflammation and Immune Mediated Diseases Laboratory of Anhui Province;The Key Laboratory of Anti-inflammatory and Immune Medicines;The Fourth Affiliated Hospital of Anhui Medical University).Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis[J].中国药理学报(英文版),2022,第2期
-
Jia-wei Li,Rong-liang Wang,Jia Xu,Kuo-yang Sun,Hui-ming Jiang,Zi-ying Sun,Zhong-yang Lv,Xing-quan Xu,Rui Wu,Hu Guo,Qing Jiang,Dong-quan Shi(State Key Laboratory of Pharmaceutical Biotechnology;Drum Tower of Clinical Medicine;Department of Sports Medicine and Joint Surgery).Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1[J].中国药理学报(英文版),2022,第2期
-
Qiu-kai Lu,Chen Fan,Cai-gui Xiang,Bing Wu,Hui-min Lu,Chun-lan Feng,Xiao-qian Yang,Heng Li,Wei Tang(Laboratory of Anti-inflammation and Immunopharmacology;School of Pharmacy).Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells[J].中国药理学报(英文版),2022,第2期
-
Fang Wang,Jia-nan Wang,Xiao-yan He,Xiao-guo Suo,Chao Li,Wei-jian Ni,Yu-ting Cai,Yuan He,Xin-yun Fang,Yu-hang Dong,Tian Xing,Ya-ru Yang,Feng Zhang,Xiang Zhong,Hong-mei Zang,Ming-ming Liu,Jun Li,Xiao-ming Meng,Juan Jin(Inflammation and Immune Mediated Diseases Laboratory of Anhui Province;Department of Pharmacy;Hospital of Stomatology;Department of Pharmacy;Department of Nephrology;School of Basic Medical Sciences).Stratifin promotes renal dysfunction in ischemic and nephrotoxic AKI mouse models via enhancing RIPK3-mediated necroptosis[J].中国药理学报(英文版),2022,第2期
-
Qiu-yan Zhang,Su-jing Xu,Jian-chang Qian,Li-bin Yang,Peng-qin Chen,Yi Wang,Xiang Hu,Ya-li Zhang,Wu Luo,Guang Liang(Chemical Biology Research Center;Medical Research Center;School and Hospital of Stomatology;Department of Endocrinology;School of Pharmaceutical Sciences;Wenzhou Institute).Pharmacological inhibition of MyD88 suppresses inflammation in tubular epithelial cells and prevents diabetic nephropathy in experimental mice[J].中国药理学报(英文版),2022,第2期
-
Xiao-ru Zhou,Xiao Li,Li-ping Liao,Jie Han,Jing Huang,Jia-cheng Li,Hong-ru Tao,Shi-jie Fan,Zhi-feng Chen,Qi Li,Shi-jie Chen,Hong Ding,Ya-xi Yang,Bing Zhou,Hua-liang Jiang,Kai-xian Chen,Yuan-yuan Zhang,Chuan-xin Huang,Cheng Luo(Drug Discovery and Design Center;University of Chinese Academy of Sciences;School of Life Science and Technology;Department of Medicinal Chemistry;Shanghai Institute of Immunology and Department of Immunology and Microbiology).P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib[J].中国药理学报(英文版),2022,第2期
-
Jian Meng,Hua Zhang,Jing-jing Bao,Zhen-dong Chen,Xiao-yun Liu,Yi-fan Zhang,Yong Jiang,Li-yan Miao,Da-fang Zhong(State Key Laboratory of Drug Research;The First Affiliated Hospital of Soochow University;Shanghai Allist Pharmaceuticals Inc.).Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans[J].中国药理学报(英文版),2022,第2期
-
De-sheng Li,Gen-long Xue,Ji-ming Yang,Chang-zhu Li,Rui-xin Zhang,Tao Tian,Zheng Li,Ke-wei Shen,Yang Guo,Xue-ning Liu,Jin Wang,Yan-jie Lu,Zhen-wei Pan(Department of Pharmacology(State-Province Key Laboratories of Biomedicine Pharmaceutics of China,Key Laboratory of Cardiovascular research,Ministry of Education),College of Pharmacy,Harbin Medical University,Harbin 150081,China).Knockout of interleukin-17A diminishes ventricular arrhythmia susceptibility in diabetic mice via inhibiting NF-KB-mediated electrical remodeling[J].中国药理学报(英文版),2022,第2期
-
Wen Li,Li-ping Liao,Ning Song,Yan-jun Liu,Yi-luan Ding,Yuan-yuan Zhang,Xiao-ru Zhou,Zhong-ya Sun,Sen-hao Xiao,Hong-bo Wang,Jing Lu,Nai-xia Zhang,Hua-liang Jiang,Kai-xian Chen,Chuan-peng Liu,Jie Zheng,Ke-hao Zhao,Cheng Luo(School of Pharmacy;Drug Discovery and Design Center;University of Chinese Academy of Sciences;Center of Immunological Diseases;Department of Gastroenterology;Department of Analytical Chemistry;School of Life Science and Technology;School of Life Science and Technology;Department of Pharmacology).Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase[J].中国药理学报(英文版),2022,第2期
-
Yi-fei Liu,Lei Zhang,Qi Wu,Lin-yin Feng(CAS Key Laboratory of Receptor Research;School of Pharmacy).Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway[J].中国药理学报(英文版),2022,第2期
-
Peng-yuan Wang,Jia-yi Feng,Zhen Zhang,Yi Chen,Zhen Qin,Xian-min Dai,Jie Wei,Bo-han Hu,Wei-dong Zhang,Yang Sun,Xia Liu(School of Pharmacy).The adipokine orosomucoid alleviates adipose tissue fibrosis via the AMPK pathway[J].中国药理学报(英文版),2022,第2期
-
Ahmed Attia Ahmed Abdelmoaty,Ping Zhang,Wen Lin,Ying-juan Fan,Sheng-nan Ye,Jian-hua Xu(Department of Pharmacology;The First Affiliated Hospital of Fujian Medical University).C0818,a novel curcumin derivative,induces ROS-dependent cytotoxicity in human hepatocellular carcinoma cells in vitro via disruption of Hsp90 function[J].中国药理学报(英文版),2022,第2期
-
Jia-yi He,Quan Hong,Bi-xia Chen,Shao-yuan Cui,Ran Liu,Guang-yan Cai,Jiao Guo,Xiang-mei Chen(Department of Nephrology;Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine).Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity[J].中国药理学报(英文版),2022,第2期
-
Tai Yu,Huang Bei,Guo Paipai,Wang Zhen,Zhou Zhengwei,Wang Manman,Sun Hanfei,Hu Yong,Xu Shenglin,Zhang Lingling,Wang Qingtong,Wei Wei.TNF-alpha impairs EP4 signaling through the association of TRAF2-GRK2 in primary fibroblast-like synoviocytes[J].中国药理学报,2022,第2期
-
Hong-chun Li,Jia-mei Zhang,Rui Xu,Yong-hai Wang,Wei Xu,Rong Chen,Xue-mei Wan,Hao-luo Zhang,Liang Wang,Xiao-jie Wang,Lin-hong Jiang,Bin Liu,Ying Zhao,Yuan-yuan Chen,Yan-ping Dai,Min Li,Hua-qin Zhang,Zhen Yang,Lin Bai,Jie Zhang,Hong-bo Wang,Jing-wei Tian,Ying-lan Zhao,Xiao-bo Cen(National Chengdu Center for Safety Evaluation of Drugs;Ministry of Education;Histology and Imaging Platform).mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1-GluA2 interaction in the nucleus accumbens[J].中国药理学报(英文版),2022,第2期
-
Li Hongchun,Zhang Jiamei,Xu Rui,Wang Yonghai,Xu Wei,Chen Rong,Wan Xuemei,Zhang Haoluo,Wang Liang,Wang Xiaojie,Jiang Linhong,Liu Bin,Zhao Ying,Chen Yuanyuan,Dai Yanping,Li Min,Zhang Huaqin,Yang Zhen,Bai Lin,Zhang Jie,Wang Hongbo,Tian Jingwei,Zhao Yinglan,Cen Xiaobo(West China Hospital,Sichuan University,National Chengdu Center for Safety Evaluation of Drugs,State Key Laboratory of Biotherapy,Collaborative Innovation Center for Biotherapy;Biotech Drugs in Universities of Shandong,Yantai University,Ministry of Education,Collaborative Innovation Center of Advanced Drug Delivery System;Histology and Imaging Platform,Core Facilities of West China Hospital,Sichuan University).mTOR regulates cocaine-induced behavioural sensitization through the SynDIGl-GluA2 interaction in the nucleus accumbens[J].Acta Pharmacologica Sinica,2022,第2期
|