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Tong-xin Huo,Xiao-ping Wang,Zhou Yu,Bo Kong,Yuan He,Qing-long Guo,Xiao-bo Zhang,Lei Qiang(State Key Laboratory of Natural Medicines;State Key Laboratory of Natural Medicines;Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs).Oroxylin A inhibits the migration of hepatocellular carcinoma cells by inducing NAG-1 expression[J].中国药理学报(英文版),2022,第3期
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Hui-min Li,Xin Liu,Zi-yu Meng,Lei Wang,Li-min Zhao,Hui Chen,Zhi-xia Wang,Hao Cui,Xue-qing Tang,Xiao-han Li,Wei-na Han,Xue Bai,Yuan Lin,Heng Liu,Yong Zhang,Bao-feng Yang(Department of Pharmacology(the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China;Department of Medicinal Chemistry and Natural Medicine Chemistry;Research Unit of Noninfectious Chronic Diseases in Frigid Zone;Institute of Metabolic Disease;Department of Pharmacology and Therapeutics).Kanglexin delays heart aging by promoting mitophagy[J].中国药理学报(英文版),2022,第3期
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Wen-xia Yang,Yu Liu,Shu-min Zhang,Hua-fen Wang,Yi-fei Liu,Jia-lu Liu,Xiao-hui Li,Meng-ru Zeng,Yu-zhang Han,Fu-you Liu,Lin Sun,Li Xiao(Department of Nephrology).Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy[J].中国药理学报(英文版),2022,第3期
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Yuan-ming He,Xiu-min Zhou,Shuo-yi Jiang,Zu-bin Zhang,Bi-yin Cao,Jin-bao Liu,Yuan-ying Zeng,Jun Zhao,Xin-liang Mao(Guangdong Key Laboratory of Protein Modification and Degradation;Department of Pharmacology;Department of Oncology;Department of Oncology;Department of Thoracic Surgery).TRIM25 activates AKT/mTOR by inhibiting PTEN via K63-linked polyubiquitination in non-small cell lung cancer[J].中国药理学报(英文版),2022,第3期
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Hong Yu,Hong-ying Gao,Hua Guo,Gui-zhen Wang,Yi-qing Yang,Qian Hu,Li-jun Liang,Qun Zhao,Da-wei Xie,Yu Rao,Guang-biao Zhou(School of Chinese Materia Medica;State Key Laboratory of Molecular Oncology;MOE Key Laboratory of Protein Sciences;Hubei University of Medicine).Upregulation of wild-type p53 by small molecule-induced elevation of NQO1 in non-small cell lung cancer cells[J].中国药理学报(英文版),2022,第3期
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Tae Woo Kim(Department of Preventive Medicine).Cinnamaldehyde induces autophagy-mediated cell death through ER stress and epigenetic modification in gastric cancer cells[J].中国药理学报(英文版),2022,第3期
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Zan Guiying,Sun Xiang,Wang Yujun,Liu Rui,Wang Chenyao,Du Weijia,Guo Liubin,Chai Jingrui,Li Qinglin,Liu Zhiqiang,Liu Jinggen.Amygdala dynorphin/kappa opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress[J].中国药理学报,2022,第3期
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An Cheng,Yi-fei Wang,Yasuharu Shinoda,Ichiro Kawahata,Tetsunori Yamamoto,Wen-bin Jia,Hanae Yamamoto,Tomohiro Mizobata,Yasushi Kawata,Kohji Fukunaga(Department of Pharmacology;Department of Chemistry and Biotechnology).Fatty acid-binding protein 7 triggers α-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress[J].中国药理学报(英文版),2022,第3期
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Yang Sun,Zi-jian Li(Department of Cardiology and Institute of Vascular Medicine;Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides;Key Laboratory of Molecular Cardiovascular Sciences;Beijing Key Laboratory of Cardiovascular Receptors Research).The multifunctional adaptor protein HIP-55 couples Smad7 to accelerate TGF-β type Ⅰ receptor degradation[J].中国药理学报(英文版),2022,第3期
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Lin-lin Chang,Yue-kang Li,Chen-xi Zhao,Chen-ming Zeng,Fu-jing Ge,Jia-min Du,Wen-zhou Zhang,Pei-hua Lu,Qiao-jun He,Hong Zhu,Bo Yang(Zhejiang Province Key Laboratory of Anti-Cancer Drug Research;Department of Pharmacy;Department of Medical Oncology).AKR1C1 connects autophagy and oxidative stress by interacting with SQSTM1 in a catalytic-independent manner[J].中国药理学报(英文版),2022,第3期
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Xu-xia Li,Peng Zhang,Yang Yang,Jing-jing Wang,Yan-jun Zheng,Ji-liang Tan,Shen-yan Liu,Yong-ming Yan,You-yi Zhang,Yong-xian Cheng,Huang-tian Yang(CAS Key Laboratory of Tissue Microenvironment and Tumor;State Key Laboratory of Phytochemistry and Plant Resources in West China;Department of Cardiology and Institute of Vascular Medicine;NHC Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides;Key Laboratory of Molecular Cardiovascular Science;School of Pharmaceutical Sciences;Department of Cardiology;Institute for Stem Cell and Regeneration).Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway[J].中国药理学报(英文版),2022,第3期
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Cheng An,Wang Yifei,Shinoda Yasuharu,Kawahata Ichiro,Yamamoto Tetsunori,Jia Wenbin,Yamamoto Hanae,Mizobata Tomohiro,Kawata Yasushi,Fukunaga Kohji.Fatty acid-binding protein 7 triggers alpha-synuclein oligomerization in glial cells and oligodendrocytes associated with oxidative stress[J].中国药理学报,2022,第3期
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Sun Yang,Li Zijian.The multifunctional adaptor protein HIP-55 couples Smad7 to accelerate TGF-beta type I receptor degradation[J].中国药理学报,2022,第3期
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Chang-ling Gu,Hai-xia Zhu,Lan Deng,Xiao-qing Meng,Kai Li,Wei Xu,Le Zhao,Yue-qin Liu,Zhen-ping Zhu,Hao-min Huang(Sunshine Guojian Pharmaceutical(Shanghai)Co.Ltd.).Bispecific antibody simultaneously targeting PD1 and HER2 inhibits tumor growth via direct tumor cell killing in combination with PD1/PDL1 blockade and HER2 inhibition[J].中国药理学报(英文版),2022,第3期
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Gui-ying Zan,Xiang Sun,Yu-jun Wang,Rui Liu,Chen-yao Wang,Wei-jia Du,Liu-bin Guo,Jing-rui Chai,Qing-lin Li,Zhi-qiang Liu,Jing-gen Liu(Department of Anesthesiology,Shanghai First Maternity and Infant Hospital,Tongji University School of Medicine,Shanghai 201204,China;Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;Key Laboratory of Xin'an Medicine,Ministry of Education,Anhui Province Key Laboratory of R&D of Chinese Medicine,Anhui University of Chinese Medicine,Hefei 230038,China;Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;Department of Anesthesiology,Shanghai First Maternity and Infant Hospital,Tongji University School of Medicine,Shanghai 201204,China;Key Laboratory of Receptor Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China).Amygdala dynorphin/K opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress[J].中国药理学报(英文版),2022,第3期
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Xiao Mo,Cheng-fei Zhang,Ping Xu,Min Ding,Zhi-jie Ma,Qi Sun,Yu Liu,Hong-kai Bi,Xin Guo,Alaa Abdelatty,Chao Hu,Hao-jun Xu,Guo-ren Zhou,Yu-liang Jia,Hong-ping Xia(Sir Run Run Hospital,Nanjing Medical University,Nanjing 211166,China;School of Basic Medical Sciences&State Key Laboratory of Reproductive Medicine&Key Laboratory of Antibody Technique of National Health Commission&Jiangsu Antibody Drug Engineering Research Center,Nanjing Medical University,Nanjing 210092,China;School of Basic Medical Sciences&State Key Laboratory of Reproductive Medicine&Key Laboratory of Antibody Technique of National Health Commission&Jiangsu Antibody Drug Engineering Research Center,Nanjing Medical University,Nanjing 210092,China;Sir Run Run Hospital,Nanjing Medical University,Nanjing 211166,China;Jiangsu Cancer Hospital&Jiangsu Institute of Cancer Research&The Affiliated Cancer Hospital of Nanjing Medical University,Nanjing 210092,China;Yijishan Hospital of Wannan Medical College,Wannan Medical College,Wuhu 241002,China;Sir Run Run Hospital,Nanjing Medical University,Nanjing 211166,China;Yijishan Hospital of Wannan Medical College,Wannan Medical College,Wuhu 241002,China;School of Basic Medical Sciences&State Key Laboratory of Reproductive Medicine&Key Laboratory of Antibody Technique of National Health Commission&Jiangsu Antibody Drug Engineering Research Center,Nanjing Medical University,Nanjing 210092,China).KCNN4-mediated Ca2+/MET/AKT axis is promising for targeted therapy of pancreatic ductal adenocarcinoma[J].中国药理学报(英文版),2022,第3期
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Lei Xu,Tian-yu Yang,Yi-wen Zhou,Mei-fei Wu,Jie Shen,Jie-ling Cheng,Qing-xue Liu,Shi-yang Cao,Jian-qing Wang,Lei Zhang(School of Pharmacy;Inflammation and Immune Mediated Diseases Laboratory of Anhui Province;The Key Laboratory of Anti-inflammatory and Immune Medicines;The Fourth Affiliated Hospital of Anhui Medical University).Author Correction:Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis[J].中国药理学报(英文版),2022,第3期
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Jia-yi He,Quan Hong,Bi-xia Chen,Shao-yuan Cui,Ran Liu,Guang-yan Cai,Jiao Guo,Xiang-mei Chen(Department of Nephrology;Guangdong Metabolic Diseases Research Center of Integrated Chinese and Western Medicine).Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity[J].中国药理学报(英文版),2022,第2期
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Qiu-yan Zhang,Su-jing Xu,Jian-chang Qian,Li-bin Yang,Peng-qin Chen,Yi Wang,Xiang Hu,Ya-li Zhang,Wu Luo,Guang Liang(Chemical Biology Research Center;Medical Research Center;School and Hospital of Stomatology;Department of Endocrinology;School of Pharmaceutical Sciences;Wenzhou Institute).Pharmacological inhibition of MyD88 suppresses inflammation in tubular epithelial cells and prevents diabetic nephropathy in experimental mice[J].中国药理学报(英文版),2022,第2期
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Ahmed Attia Ahmed Abdelmoaty,Ping Zhang,Wen Lin,Ying-juan Fan,Sheng-nan Ye,Jian-hua Xu(Department of Pharmacology;The First Affiliated Hospital of Fujian Medical University).C0818,a novel curcumin derivative,induces ROS-dependent cytotoxicity in human hepatocellular carcinoma cells in vitro via disruption of Hsp90 function[J].中国药理学报(英文版),2022,第2期
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Fang Wang,Jia-nan Wang,Xiao-yan He,Xiao-guo Suo,Chao Li,Wei-jian Ni,Yu-ting Cai,Yuan He,Xin-yun Fang,Yu-hang Dong,Tian Xing,Ya-ru Yang,Feng Zhang,Xiang Zhong,Hong-mei Zang,Ming-ming Liu,Jun Li,Xiao-ming Meng,Juan Jin(Inflammation and Immune Mediated Diseases Laboratory of Anhui Province;Department of Pharmacy;Hospital of Stomatology;Department of Pharmacy;Department of Nephrology;School of Basic Medical Sciences).Stratifin promotes renal dysfunction in ischemic and nephrotoxic AKI mouse models via enhancing RIPK3-mediated necroptosis[J].中国药理学报(英文版),2022,第2期
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Jian Meng,Hua Zhang,Jing-jing Bao,Zhen-dong Chen,Xiao-yun Liu,Yi-fan Zhang,Yong Jiang,Li-yan Miao,Da-fang Zhong(State Key Laboratory of Drug Research;The First Affiliated Hospital of Soochow University;Shanghai Allist Pharmaceuticals Inc.).Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans[J].中国药理学报(英文版),2022,第2期
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Peng-yuan Wang,Jia-yi Feng,Zhen Zhang,Yi Chen,Zhen Qin,Xian-min Dai,Jie Wei,Bo-han Hu,Wei-dong Zhang,Yang Sun,Xia Liu(School of Pharmacy).The adipokine orosomucoid alleviates adipose tissue fibrosis via the AMPK pathway[J].中国药理学报(英文版),2022,第2期
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Xiao-ru Zhou,Xiao Li,Li-ping Liao,Jie Han,Jing Huang,Jia-cheng Li,Hong-ru Tao,Shi-jie Fan,Zhi-feng Chen,Qi Li,Shi-jie Chen,Hong Ding,Ya-xi Yang,Bing Zhou,Hua-liang Jiang,Kai-xian Chen,Yuan-yuan Zhang,Chuan-xin Huang,Cheng Luo(Drug Discovery and Design Center;University of Chinese Academy of Sciences;School of Life Science and Technology;Department of Medicinal Chemistry;Shanghai Institute of Immunology and Department of Immunology and Microbiology).P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib[J].中国药理学报(英文版),2022,第2期
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Wen Li,Li-ping Liao,Ning Song,Yan-jun Liu,Yi-luan Ding,Yuan-yuan Zhang,Xiao-ru Zhou,Zhong-ya Sun,Sen-hao Xiao,Hong-bo Wang,Jing Lu,Nai-xia Zhang,Hua-liang Jiang,Kai-xian Chen,Chuan-peng Liu,Jie Zheng,Ke-hao Zhao,Cheng Luo(School of Pharmacy;Drug Discovery and Design Center;University of Chinese Academy of Sciences;Center of Immunological Diseases;Department of Gastroenterology;Department of Analytical Chemistry;School of Life Science and Technology;School of Life Science and Technology;Department of Pharmacology).Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase[J].中国药理学报(英文版),2022,第2期
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Qiu-kai Lu,Chen Fan,Cai-gui Xiang,Bing Wu,Hui-min Lu,Chun-lan Feng,Xiao-qian Yang,Heng Li,Wei Tang(Laboratory of Anti-inflammation and Immunopharmacology;School of Pharmacy).Inhibition of PDE4 by apremilast attenuates skin fibrosis through directly suppressing activation of M1 and T cells[J].中国药理学报(英文版),2022,第2期
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Jia-wei Li,Rong-liang Wang,Jia Xu,Kuo-yang Sun,Hui-ming Jiang,Zi-ying Sun,Zhong-yang Lv,Xing-quan Xu,Rui Wu,Hu Guo,Qing Jiang,Dong-quan Shi(State Key Laboratory of Pharmaceutical Biotechnology;Drum Tower of Clinical Medicine;Department of Sports Medicine and Joint Surgery).Methylene blue prevents osteoarthritis progression and relieves pain in rats via upregulation of Nrf2/PRDX1[J].中国药理学报(英文版),2022,第2期
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Yi-fei Liu,Lei Zhang,Qi Wu,Lin-yin Feng(CAS Key Laboratory of Receptor Research;School of Pharmacy).Paeoniflorin ameliorates ischemic injury in rat brain via inhibiting cytochrome c/caspase3/HDAC4 pathway[J].中国药理学报(英文版),2022,第2期
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Lei Xu,Tian-yu Yang,Yi-wen Zhou,Mei-fei Wu,Jie Shen,Jie-ling Cheng,Qing-xue Liu,Shi-yang Cao,Jian-qing Wang,Lei Zhang(School of Pharmacy;Inflammation and Immune Mediated Diseases Laboratory of Anhui Province;The Key Laboratory of Anti-inflammatory and Immune Medicines;The Fourth Affiliated Hospital of Anhui Medical University).Bmal1 inhibits phenotypic transformation of hepatic stellate cells in liver fibrosis via IDH1/α-KG-mediated glycolysis[J].中国药理学报(英文版),2022,第2期
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Hong-chun Li,Jia-mei Zhang,Rui Xu,Yong-hai Wang,Wei Xu,Rong Chen,Xue-mei Wan,Hao-luo Zhang,Liang Wang,Xiao-jie Wang,Lin-hong Jiang,Bin Liu,Ying Zhao,Yuan-yuan Chen,Yan-ping Dai,Min Li,Hua-qin Zhang,Zhen Yang,Lin Bai,Jie Zhang,Hong-bo Wang,Jing-wei Tian,Ying-lan Zhao,Xiao-bo Cen(National Chengdu Center for Safety Evaluation of Drugs;Ministry of Education;Histology and Imaging Platform).mTOR regulates cocaine-induced behavioural sensitization through the SynDIG1-GluA2 interaction in the nucleus accumbens[J].中国药理学报(英文版),2022,第2期
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