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期刊文章列表

  • Shuang Cui,Huijian Hu,An Chen,Ming Cui,Xiaojie Pan,Pengfei Zhang,Guangji Wang,Hong Wang,Haiping Hao(State Key Laboratory of Natural Medicines,Key Laboratory of Drug Metabolism&Pharmacokinetics,China Pharmaceutical University).SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXR[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Xiaolin Zhang1,2,Xueyan Zhen1,2,Yixuan Yang1,2,Quan Feng1,2,Wanqing Yuan1,2,Xiaoyu Xie1,2(School of Pharmacy,Health Science Center,Xi'an Jiaotong University;Shaanxi Engineering Research Center of Cardiovascular Drugs Screening&Analysis).Precise assembly of inside-out cell membrane camouflaged nanoparticles via bioorthogonal reactions for improving drug leads capturing[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Zhifu Xie1,Mei Zhang1,Qian Song1,2,Long Cheng1,2,Xinwen Zhang1,Gaolei Song1,2,Xinyu Sun1,Min Gu1,Chendong Zhou1,Yangming Zhang1,3,Kexin Zhu1,Jianpeng Yin4,Xiaoyan Chen1,Jingya Li1,2,Fajun Nan1,2,4(State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Burgeon Therapeutics Co.,Ltd.;Drug Discovery Shandong Laboratory,Bohai Rim Advanced Research Institute for Drug Discovery).Development of the novel ACLY inhibitor 326E as a promising treatment for hypercholesterolemia[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Lingyan Wang1,2,Guiyang Xia1,Huan Xia1,Xiaohong Wei1,Yanan Wang2,Sheng Lin1(Key Laboratory of Chinese Internal Medicine of Ministry of Education and Beijing,Dongzhimen Hospital,Beijing University of Chinese Medicine;State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College).(+)/(-)-Yanhusamides A-C, three pairs of unprecedented benzylisoquinoline-pyrrole hetero-dimeric alkaloid enantiomers from Corydalis yanhusuo[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Jian Lu,Xuyang Shang,Bingyi Yao,Dongyi Sun,Jie Liu,Yuanjin Zhang,He Wang,Jingru Shi,Huaqing Chen,Tieliu Shi,Mingyao Liu,Xin Wang(Changning Maternity and Infant Health Hospital and School of Life Sciences,Shanghai Key Laboratory of Regulatory Biology,East China Normal University).The role of CYP1A1/2 in cholesterol ester accumulation provides a new perspective for the treatment of hypercholesterolemia[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Dayuan Wang1,Xiao Gu1,Xinyi Ma1,Jun Chen2,Qizhi Zhang2,Zhihua Yu1,Juan Li1,Meng Hu1,Xiaofang Tan1,Yuyun Tang1,Jianrong Xu1,3,Minjun Xu2,Qingxiang Song1,Huahua Song1,Gan Jiang1,Zaiming Tang4,Xiaoling Gao1,Hongzhuan Chen1,3(Department of Pharmacology and Chemical Biology,State Key Laboratory of Oncogenes and Related Genes,Shanghai Universities Collaborative Innovation Center for Translational Medicine,Shanghai Jiao Tong University School of Medicine;Key Laboratory of Smart Drug Delivery,Ministry of Education,School of Pharmacy,Fudan University;Shanghai Frontiers Science Center of TCM Chemical Biology,Institute of Interdisciplinary Integrative Medicine Research,Shanghai University of Traditional Chinese Medicine;Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education,Shanghai Jiao Tong University School of Medicine).Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yang Liu1,Ting Liu2,Yuanzhang Zhou2,Wenjie Li2,Min Wang3,Nanshan Song2,Wenbin Zhang4,Jingwei Jiang5,Shengtao Yuan5,Jianhua Ding2,Gang Hu2,1,Ming Lu2(Department of Pharmacology,School of Medicine and Holistic Integrative Medicine,Nanjing University of Chinese Medicine;Jiangsu Key Laboratory of Neurodegeneration,Department of Pharmacology,Nanjing Medical University;Department of Geriatrics,Affiliated Brain Hospital of Nanjing Medical University;Department of Neurosurgery,Affiliated Brain Hospital of Nanjing Medical University;Jiangsu Key Laboratory of Drug Screening,China Pharmaceutical University).Impeding the combination of astrocytic ASCT2 and NLRP3 by talniflumate alleviates neuroinflammation in experimental models of Parkinson’s disease[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Nazi Song1,Hongjiao Xu1,Shuohan Wu1,Suijia Luo2,Jingyao Xu1,Qian Zhao1,Rui Wang3,4,Xianxing Jiang1(School of Pharmaceutical Sciences,Sun Yat-sen University;Shenzhen Turier Biotech.Co.,Ltd.;State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences&Peking Union Medical College;School of Life Sciences,Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences&Research Unit of Peptide Science,Lanzhou University).Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs-EBP interaction recover NAFLD through enhancing mitochondrial function in mice[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yeuan Ting Lee,Yi Jer Tan,Chern Ein Oon(Institute for Research in Molecular Medicine (INFORMM),Universiti Sains Malaysia).Benzimidazole and its derivatives as cancer therapeutics:The potential role from traditional to precision medicine[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Dan Wang1,2,Bochuan Deng1,2,Lu Cheng1,2,Jieru Li1,2,Jiao Zhang1,2,Xiang Zhang1,2,Xiaomin Guo1,2,Tiantian Yan1,2,Xin Yue1,2,Yingying An1,2,Bangzhi Zhang1,2,Wenle Yang1,2,Junqiu Xie1,2,Rui Wang1,2(Institute of Materia Medica and Research Unit of Peptide Science,Chinese Academy of Medical Sciences,Peking Union Medical College;Key Laboratory of Preclinical Study for New Drugs of Gansu Province,School of Basic Medical Sciences,Lanzhou University).A novel and low-toxic peptide DR3penA alleviates pulmonary fibrosis by regulating the MAPK/miR-23b-5p/AQP5 signaling axis[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Huaan Li1,2,Fei Peng3,Xiaohui Yan4,Chun Mao5,Xing Ma6,Daniela A.Wilson7,Qiang He8,Yingfeng Tu1,2(Department of Pharmacy,Zhujiang Hospital,Southern Medical University;School of Pharmaceutical Science,Guangdong Provincial Key Laboratory of New Drug Screening,Southern Medical University;School of Materials Science and Engineering,Sun Yat-Sen University;State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics&Centre for Molecular Imaging and Translational Medicine,School of Public Health,Xiamen University;National and Local Joint Engineering Research Center of Biomedical Functional Materials,School of Chemistry and Materials Science,Nanjing Normal University;Sauvage Laboratory for Smart Materials,School of Materials Science and Engineering,Harbin Institute of Technology(Shenzhen);Institute for Molecules and Materials,Radboud University;Key Laboratory of Microsystems and Microstructures Manufacturing(Ministry of Education),School of Medicine and Health,Harbin Institute of Technology).Medical micro-and nanomotors in the body[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Wenhui Wang1,Pengyu Liu2,Yalin Zhang3,Li Yan3,Michael X.Zhu4,Jin Wang3,Ye Yu3(Department of Pharmacology,School of Pharmacy,China Pharmaceutical University;Department of Medical Genetics and Developmental Biology,School of Medicine,the Key Laboratory of Developmental Genes and Human Diseases,Ministry of Education,Southeast University;School of Basic Medicine and Clinical Pharmacy and State Key Laboratory of Natural Medicines,China Pharmaceutical University;Department of Integrative Biology and Pharmacology,McGovern Medical School,the University of Texas Health Science Center at Houston).Expression and functions of transient receptor potential channels in liver diseases[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yijun Chen,Kaiming Li,Mengying Jiao,Yingshuang Huang,Zihao Zhang,Lingjing Xue,Caoyun Ju,Can Zhang(State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases,Center of Advanced Pharmaceuticals and Biomaterials,China Pharmaceutical University).Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Qianhua Feng1,2,Yutong Hao1,Shuaiqi Yang1,Xiaomin Yuan1,Jing Chen1,Yuying Mei1,Lanlan Liu3,Junbiao Chang2,4,Zhenzhong Zhang1,2,Lei Wang1,2(School of Pharmaceutical Sciences,Zhengzhou University;Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases;Department of Pharmacy,The Third Affiliated Hospital of Zhengzhou University;College of Chemistry,Zhengzhou University).A metabolic intervention strategy to break evolutionary adaptability of tumor for reinforced immunotherapy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Jizhou Tan1,2,Ting Liu3,4,Wenzhe Fan1,Jialiang Wei1,Bowen Zhu1,Yafang Liu2,Lingwei Liu1,Xiaokai Zhang1,Songling Chen2,Haibiao Lin3,4,Yuanqing Zhang5,Jiaping Li1(Department of Interventional Oncology,the First Affiliated Hospital,Sun Yat-sen University;Department of Stomatology,the First Affiliated Hospital,Sun Yat-sen University;Department of Laboratory Medicine,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangdong Provincial Hospital of Traditional,Chinese Medicine;Second Clinical Medical College,Guangzhou University of Chinese Medicine;School of Pharmaceutical Sciences,Sun Yat-sen University).Anti-PD-L1 antibody enhances curative effect of cryoablation via antibody-dependent cell-mediated cytotoxicity mediating PD-L1highCD11b+cells elimination in hepatocellular carcinoma[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Di Zhao1,2,Jing Zhang1,Lingyuan Zhang1,Qingnan Wu1,2,3,Yan Wang1,2,3,Weimin Zhang1,2,4,Yuanfan Xiao1,Jie Chen1,2,3,Qimin Zhan1,2,3,4(Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Laboratory of Molecular Oncology,Peking University Cancer Hospital&Institute;Research Unit of Molecular Cancer Research,Chinese Academy of Medical Sciences;Peking University International Cancer Institute;Shenzhen Bay Laboratory).PAFR/Stat3 axis maintains the symbiotic ecosystem between tumor and stroma to facilitate tumor malignancy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Jianjun Cheng1,2,3,Haitian Zhao1,4,5,Bin Li6,Hua Zhang2,Qianyu Zhao1,2,Shiyao Fu1,2,Ying Han1,2,Weihong Lu1,4,5,Jiahua Shi3,Xin Yang1,2,4,5(School of Medicine and Health,Harbin Institute of Technology;School of Chemistry and Chemical Engineering,Harbin Institute of Technology;Key Laboratory of Natural Medicine and Immune-Engineering of Henan Province,Henan University;Chongqing Research Institute,Harbin Institute of Technology;National and Local Joint Engineering Laboratory for Synthesis,Transformation and Separation of Extreme Environmental Nutrients;Academician Workstation,Jiangxi University of Chinese Medicine).Photosensitive pro-drug nanoassemblies harboring a chemotherapeutic dormancy function potentiates cancer immunotherapy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Ze Mi1,Qing Yao1,2,3,Yan Qi2,Jinhai Zheng4,Jiahao Liu1,Zhenguo Liu1,Hongpei Tan1,Xiaoqian Ma1,Wenhu Zhou1,5,6,Pengfei Rong1,6(Department of Radiology,The Third Xiangya Hospital,Central South University;Department of Pathology,Shihezi University School of Medicine and the First Affiliated Hospital to Shihezi University School of Medicine;Department of Pathology,Cangzhou Central Hospital&the Affiliated to Hebei Medical University;School of Biomedical Sciences,Hunan University;Xiangya School of Pharmaceutical Sciences,Central South University;Key Laboratory of Biological Nanotechnology of National Health Commission).Salmonella-mediated blood-brain barrier penetration, tumor homing and tumor microenvironment regulation for enhanced chemo/bacterial glioma therapy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Zhengjie Lu1,2,Yu Guo1,3,Dan Xu1,3,Hao Xiao2,3,Yongguo Dai1,Kexin Liu1,Liaobin Chen2,3,Hui Wang1,3(Department of Pharmacology,Wuhan University School of Basic Medical Science;Department of Orthopedic Surgery,Zhongnan Hospital of Wuhan University;Hubei Provincial Key Laboratory of Developmentally Originated Disorder).Developmental toxicity and programming alterations of multiple organs in offspring induced by medication during pregnancy[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yin Feng1,2,Yefan Han1,2,Anni Hu1,2,Yi Qu1,2,Yili Hu3,Hao Wu1,Xinzhi Wang1,2,Li He4(College of Pharmacy,Nanjing University of Chinese Medicine;China Jiangsu Key Laboratory of Research and Development in Marine Bio-resource Pharmaceutics;Experiment Center for Science and Technology,Nanjing University of Chinese Medicine;Department of Hematology,Zhongnan Hospital of Wuhan University).Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yujun Zhou1,Jingshu Tang1,Jiaqi Lan1,Yong Zhang1,Hongyue Wang1,Qiuyu Chen1,Yuying Kang1,Yang Sun2,Xinhong Feng3,Lei Wu1,Hongtao Jin4,5,Shizhong Chen2,Ying Peng1(State Key Laboratory of Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences&Peking Union Medical College;Department of Natural Medicines,School of Pharmaceutical Sciences,Peking University;Department of Neurology,Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University;New Drug Safety Evaluation Center,Institute of Materia Medica,Chinese Academy of Medical Sciences&Peking Union Medical College;NMPA Key Laboratory for Safety Research and Evaluation of Innovative Drug).Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Changpei Gan1,Jing Wang1,Alejandra Martínez-Chávez1,2,Michel Hillebrand2,Niels de Vries2,Joke Beukers2,Els Wagenaar1,Yaogeng Wang1,Maria C.Lebre1,Hilde Rosing2,Sjoerd Klarenbeek3,Rahmen Bin Ali4,Colin Pritchard4,Ivo Huijbers4,5,Jos H.Beijnen1,2,6,Alfred H.Schinkel1(Division of Pharmacology,the Netherlands Cancer Institute;Department of Pharmacy&Pharmacology,the Netherlands Cancer Institute;Experimental Animal Pathology Facility,the Netherlands Cancer Institute;Mouse Clinic for Cancer and Aging(MCCA)Transgenic Facility,the Netherlands Cancer Institute;Faculty of Science,Swammerdam Institute for Life Sciences,University of Amsterdam;Division of Pharmacoepidemiology and Clinical Pharmacology,Utrecht Institute for Pharmaceutical Sciences,Utrecht University).Carboxylesterase 1 family knockout alters drug disposition and lipid metabolism[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Siyuan Tang1,Miguel Garzon Sanz1,Oliver Smith1,Andreas Kr?mer2,3,4,5,Daniel Egbase,Paul W.Caton,Stefan Knapp2,3,4,5,Sam Butterworth1(Division of Pharmacy and Optometry,School of Health Sciences,Manchester Academic Health Sciences Centre,University of Manchester;Structural Genomics Consortium(SGC);Buchmann Institute for Life Sciences(BMLS);Institut für Pharmazeutische Chemie,Goethe University;Frankfurt Cancer Institute(FCI);Department of Diabetes,School of Cardiovascular and Metabolic Medicine&Sciences,Faculty of Life Sciences&Medicine,King’s College London).Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators[J].Acta Pharmaceutica Sinica B,2023,第2期
  • Yizhen Wang1,Qijun Lv1,You Chen2,Langtao Xu2,Miao Feng2,Zhiyong Xiong1,Jiajun Li1,Jie Ren3,Jie Liu2,Bo Liu1(Department of General Surgery,the Third Affiliated Hospital of Sun Yat-sen University;School of Biomedical Engineering,Sun Yat-sen University;Department of Ultrasound,the Third Affiliated Hospital of Sun Yat-sen University).Bilayer hydrogel dressing with lysozymeenhanced photothermal therapy for biofilm eradication and accelerated chronic wound repair[J].Acta Pharmaceutica Sinica B,2023,第1期
  • Panat Yanpiset1,2,3,Chayodom Maneechote1,3,Sirawit Sriwichaiin1,2,3,Natthaphat Siri-Angkul1,2,3,Siriporn C.Chattipakorn1,3,4,Nipon Chattipakorn1,2,3(Cardiac Electrophysiology Research and Training Center,Faculty of Medicine,Chiang Mai University;Cardiac Electrophysiology Unit,Department of Physiology,Faculty of Medicine,Chiang Mai University;Center of Excellence in Cardiac Electrophysiology Research,Chiang Mai University;Department of Oral Biology and Diagnostic Sciences,Faculty of Dentistry,Chiang Mai University).Gasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury:Cumulative evidence for future cardioprotective strategies[J].Acta Pharmaceutica Sinica B,2023,第1期
  • Lili Sun1,Jie Zhang2,Changshan Niu3,Cassandra E.Deering-Rice1,Ronald W.Hughen2,John G.Lamb1,Katherine Rose1,Kevin M.Chase4,Marysol Almestica-Roberts1,Markel Walter2,Eric W.Schmidt3,Alan R.Light2,Baldomero M.Olivera4,Christopher A.Reilly1(Department of Pharmacology and Toxicology,Center for Human Toxicology,University of Utah;Department of Anesthesiology,School of Medicine,University of Utah;Department of Medicinal Chemistry,University of Utah;School of Biological Sciences,University of Utah).CYP1B1-derived epoxides modulate the TRPA1channel in chronic pain[J].Acta Pharmaceutica Sinica B,2023,第1期
  • Shijin Hong1,Shuai Li1,Xiaoyan Meng2,Ping Li1,Xun Wang1,Mengxiang Su3,Xiaodong Liu1,Li Liu1(Center of Drug Metabolism and Pharmacokinetics,School of Pharmacy,China Pharmaceutical University;Tianjin Institutes of Pharmaceutical Research;Departments of Pharmaceutical Analysis,School of Pharmacy,China Pharmaceutical University).Bile duct ligation differently regulates protein expressions of organic cation transporters in intestine, liver and kidney of rats through activation of farnesoid X receptor by cholate and bilirubin[J].Acta Pharmaceutica Sinica B,2023,第1期
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