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Mengwen Huang1,Miaomiao Zhang1,2,Hongbin Zhu1,3,Xiaojiao Du4,Jun Wang1,2,5(School of Biomedical Sciences and Engineering,South China University of Technology,Guangzhou International Campus;National Engineering Research Center for Tissue Restoration and Reconstruction,South China University of Technology;Guangdong Provincial Key Laboratory of Biomedical Engineering,South China University of Technology;School of Medicine,South China University of Technology;Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education,South China University of Technology).Mucosal vaccine delivery:A focus on the breakthrough of specific barriers[J].Acta Pharmaceutica Sinica B,2022,第9期
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Shaoxing Guan1,Xi Chen2,Youhao Chen1,Guohui Wan1,Qibiao Su3,Heng Liang1,Yunpeng Yang2,Wenfeng Fang2,Yan Huang2,Hongyun Zhao2,Wei Zhuang4,Shu Liu1,2,Fei Wang5,Wei Feng1,Xiaoxu Zhang1,Min Huang1,Xueding Wang1,Li Zhang2(Laboratory of Drug Metabolism and Pharmacokinetics,School of Pharmaceutical Sciences,Sun Yat-sen University;State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yatsen University Cancer Center;College of Health Science,Guangdong Pharmaceutical University;Sun Yat-sen Memorial Hospital,Sun Yat-sen University;Ersha Department of Pharmacy,the Second Affiliated Hospital of Guangzhou University of Chinese Medicine).FOXO3 mutation predicting gefitinib-induced hepatotoxicity in NSCLC patients through regulation of autophagy[J].Acta Pharmaceutica Sinica B,2022,第9期
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Rui Cui1,2,Luo Wang1,Dongyun Zhang1,Kun Zhang3,4,Jianping Dou1,Linan Dong1,Yixuan Zhang1,Jiapeng Wu1,Longfei Tan5,Jie Yu1,Ping Liang1(Department of Interventional Ultrasound,PLA General Hospital;Department of Medical Ultrasonics,the Sixth Affiliated Hospital,Sun Yat-sen University;Laboratory of Controllable Preparation and App Department of Medical Ultrasound,Shanghai Tenth People's Hospital,Tongji University School of Medicine;Ultrasound Research and Education Institute,Tongji University School of Medicine;Laboratory of Controllable Preparation and Application of Nanomaterials,Key Laboratory of Cryogenics,Technical Institute of Physics and Chemistry,Chinese Academy of Sciences).Combination therapy using microwave ablation and D-mannose-chelated iron oxide nanoparticles inhibits hepatocellular carcinoma progression[J].Acta Pharmaceutica Sinica B,2022,第9期
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Xiaohong Cen1,Baoqu Wang1,Yuqing Liang1,Yanlin Chen1,Yu Xiao1,Shaohua Du2,Kutty Selva Nandakumar1,Hang Yin3,Shuwen Liu1,Kui Cheng1,2(Guangdong Provincial Key Laboratory of New Drug Screening and State Key Laboratory of Organ Failure Research,School of Pharmaceutical Sciences,Southern Medical University;Department of Musculoskeletal Oncology,the Third Affiliated Hospital of Southern Medical University;School of Pharmaceutical Sciences,Beijing Advanced Innovation Center for Structural Biology,Tsinghua-Peking Joint Center for Life Sciences,Tsinghua University).Small molecule SMU-CX24 targeting toll-like receptor 3 counteracts inflammation:A novel approach to atherosclerosis therapy[J].Acta Pharmaceutica Sinica B,2022,第9期
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Hongyu Wu1,Hong Yao1,Chen He1,Yilin Jia1,Zheying Zhu2,Shengtao Xu1,Dahong Li3,Jinyi Xu1(State Key Laboratory of Natural Medicines,Department of Medicinal Chemistry,China Pharmaceutical University;Division of Molecular Therapeutics & Formulation,School of Pharmacy,the University of Nottingham;Key Laboratory of Structure-Based Drug Design & Discovery,Ministry of Education,School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University).Molecular glues modulate protein functions by inducing protein aggregation:A promising therapeutic strategy of small molecules for disease treatment[J].Acta Pharmaceutica Sinica B,2022,第9期
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Yanqiu Gu,Rong Wang,Panpan Chen,Shengnan Li,Xinyi Chai2,3,Chun Chen,Yue Liu2,3,Yan Cao2,3,Diya Lv2,3,Zhanying Hong2,3,Zhenyu Zhu2,3,Yifeng Chai2,3,Yongfang Yuan,Xiaofei Chen2,3(Department of Pharmacy,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University,School of Medicine;School of Pharmacy,Naval Medical University (Second Military Medical University);Shanghai Key Laboratory for Pharmaceutical Metabolite Research).In situ synthesis and unidirectional insertion of membrane proteins in liposome-immobilized silica stationary phase for rapid preparation of microaffinity chromatography[J].Acta Pharmaceutica Sinica B,2022,第9期
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Fenglin Li1,Yi Lai2,Jiayi Ye2,Madiha Saeed2,Yijing Dang1,Zhifeng Zou1,Fangmin Chen2,Wen Zhang1,Zhiai Xu1(School of Chemistry and Molecular Engineering,East China Normal University;State Key Laboratory of Drug Research & Center of Pharmaceutics,Shanghai Institute of Materia Medica,Chinese Academy of Sciences).Dual-targeting prodrug nanotheranostics for NIR-Ⅱ fluorescence imaging-guided photo-immunotherapy of glioblastoma[J].Acta Pharmaceutica Sinica B,2022,第9期
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Xiaojie Chen1,2,Xudong Fan1,Yue Zhang1,Yinghui Wei1,Hangsheng Zheng1,Dandan Bao3,Hengwu Xu,Ji-Gang Piao1,2,5,Fanzhu Li1,2,Hongyue Zheng6(School of Pharmaceutical Sciences,Zhejiang Chinese Medical University;Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University;Department of Dermatology & Cosmetology,The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine);Department of Pharmacy,Jinhua People’s Hospital;Academy of Chinese Medical Sciences,Zhejiang Chinese Medical University;Libraries of Zhejiang Chinese Medical University,Zhejiang Chinese Medical University).Cooperative coordination-mediated multi-component self-assembly of "all-in-one" nanospike theranostic nano-platform for MRI-guided synergistic therapy against breast cancer[J].Acta Pharmaceutica Sinica B,2022,第9期
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Jian Sun1,2,3,Tongzhu Jin1,2,Zhihui Niu1,2,Jiayu Guo1,2,Yingying Guo1,2,Ruoxuan Yang1,2,Qianqian Wang1,2,Huiying Gao1,2,Yuhan Zhang1,2,Tianyu Li1,2,Wenxin He4,Zhixin Li4,Wenchao Ma1,2,Wei Su1,2,Liangliang Li1,2,Xingxing Fan5,Hongli Shan1,2,6,Haihai Liang1,2,6(Department of Pharmacology (State-Province Key Laboratories of Biomedicine-Pharmaceutics of China,Key Laboratory of Cardiovascular Research,Ministry of Education),College of Pharmacy,Harbin Medical University;Northern Translational Medicine Research and Cooperation Center,Heilongjiang Academy of Medical Sciences,Harbin Medical University;Zhuhai People's Hospital,Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment,Zhuhai Hospital Affiliated with Jinan University,Jinan University;Department of Thoracic Surgery,Shanghai Pulmonary Hospital,Tongji University;State Key Laboratory of Quality Research in Chinese Medicine/Macau Institute for Applied Research in Medicine and Health,Macau University of Science and Technology;Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070),Chinese Academy of Medical Sciences).LncRNA DACH1 protects against pulmonary fibrosis by binding to SRSF1 to suppress CTNNB1 accumulation[J].Acta Pharmaceutica Sinica B,2022,第9期
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Xiaoyuan Mao1,2,3,4,Xuan Wang5,Mingzhu Jin6,Qin Li1,2,3,4,Jining Jia1,2,3,4,Menghuan Li5,7,Honghao Zhou1,2,3,4,Zhaoqian Liu1,2,3,4,Weilin Jin8,Yanli Zhao7,Zhong Luo5(Department of Clinical Pharmacology,Xiangya Hospital,Central South University;Institute of Clinical Pharmacology,Central South University,Hunan Key Laboratory of Pharmacogenetics;Engineering Research Center of Applied Technology of Pharmacogenomics,Ministry of Education;National Clinical Research Center for Geriatric Disorders;School of Life Science,Chongqing University;Department of Gynecology and Obstetrics,Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine;Division of Chemistry and Biological Chemistry,School of Physical and Mathematical Sciences,Nanyang Technological University;Institute of Cancer Neuroscience,Medical Frontier Innovation Research Center,the First Hospital of Lanzhou University,the First Clinical Medical College of Lanzhou University).Critical involvement of lysyl oxidase in seizure-induced neuronal damage through ERK-Alox5-dependent ferroptosis and its therapeutic implications[J].Acta Pharmaceutica Sinica B,2022,第9期
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Lu Miao1,Wei Zhou1,Chunyu Yan1,Yuebin Zhang2,Qinglong Qiao1,Xuelian Zhou1,Yingzhu Chen1,Guangying Wang1,Zhendong Guo3,Jun Liu3,Hailong Piao1,Xia Pan4,Mengxue Yan4,Weijie Zhao4,Guohui Li2,Yueqing Li4,Zhaochao Xu1(CAS Key Laboratory of Separation Science for Analytical Chemistry,Dalian Institute of Chemical Physics,Chinese Academy of Sciences;State Key Laboratory of Molecular Reaction Dynamics,Dalian Institute of Chemical Physics,Chinese Academy of Sciences;Institute of Military Veterinary Science,The Academy of Military Medical Science of PLA;State Key Laboratory of Fine Chemicals,Department of Pharmaceutical Sciences,School of Chemical Engineering,Dalian University of Technology).Rapid screening of SARS-CoV-2 inhibitors via ratiometric fluorescence of RBD-ACE2 complexes in living cells by competitive binding[J].Acta Pharmaceutica Sinica B,2022,第9期
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Xuan Wang,Peng Hua,Chengwei He,Meiwan Chen(State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau).Non-apoptotic cell death-based cancer therapy:Molecular mechanism,pharmacological modulators,and nanomedicine[J].Acta Pharmaceutica Sinica B,2022,第9期
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Robert Pomponio1,Qi Tang2,Anthony Mei2,Anne Caron3,Bema Coulibaly3,Joachim Theilhaber4,Maximilian Rogers-Grazado4,Michele Sanicola-Nadel5,Souad Naimi3,Reza Olfati-Saber2,Cecile Combeau1,Jack Pollard4,Tun Tun Lin5,Rui Wang1(Sanofi Translational Medicine Early Development Cambridge;Sanofi Artificial Intelligence and Deep Analytics Data and Data Sciences;Sanofi Translational Science;Sanofi Precision Oncology Cambridge;Sanofi Oncology Early Development Cambridge).An integrative approach of digital image analysis and transcriptome profiling to explore potential predictive biomarkers for TGFβ blockade therapy[J].Acta Pharmaceutica Sinica B,2022,第9期
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Haijun Yu1,Zhiyong Qian2(Center of Pharmaceutics,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University,Collaborative Innovation Center of Biotherapy).Editorial of Special Column on A New Era of Nanobiomaterial-based Drug Delivery[J].Acta Pharmaceutica Sinica B,2022,第9期
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Zheng-Wei Zhang1,Chun-Sheng Gao2,Heng Zhang3,Jian Yang4,5,Ya-Ping Wang4,5,Li-Bin Pan1,Hang Yu1,Chi-Yu He1,Hai-Bin Luo6,Zhen-Xiong Zhao1,Xin-Bo Zhou7,Yu-Li Wang2,Jie Fu1,Pei Han1,Yu-Hui Dong3,Gang Wang4,5,Song Li6,Yan Wang1,Jian-Dong Jiang1,Wu Zhong7(State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences/Peking Union Medical College;Beijing Institute of Pharmacology and Toxicology;Beijing Synchrotron Radiation Facility,Institute of High Energy Physics,Chinese Academy of Sciences;The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders,Beijing Anding Hospital,Capital Medical University;Advanced Innovation Center for Human Brain Protection,Capital Medical University;School of Pharmaceutical Sciences,Hainan University;National Engineering Research Center for the Emergence Drugs).Morinda officinalis oligosaccharides increase serotonin in the brain and ameliorate depression via promoting 5-hydroxytryptophan production in the gut microbiota[J].Acta Pharmaceutica Sinica B,2022,第8期
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Yingping Zeng,Sufen Li,Shufen Zhang,Li Wang,Hong Yuan,Fuqiang Hu(College of Pharmaceutical Science,Zhejiang University).Cell membrane coated-nanoparticles for cancer immunotherapy[J].Acta Pharmaceutica Sinica B,2022,第8期
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Wenfeng Jia1,Rui Liu1,Yushan Wang1,Chuan Hu1,Wenqi Yu1,Yang Zhou1,Ling Wang1,Mengjiao Zhang1,Huile Gao1,Xiang Gao2(Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry,Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University;Department of Neurosurgery and Institute of Neurosurgery,State Key Laboratory of Biotherapy,West China Hospital,West China Medical School,Sichuan University and Collaborative Innovation Center for Biotherapy).Dual-responsive nanoparticles with transformable shape and reversible charge for amplified chemo-photodynamic therapy of breast cancer[J].Acta Pharmaceutica Sinica B,2022,第8期
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Rongfang Wei1,2,Xing Cui3,Jie Min2,Zigen Lin2,Yanyan Zhou2,Mengjie Guo2,Xiaojuan An2,Hao Liu2,Siegfried Janz4,Chunyan Gu1,2,Hongbo Wang5,6,Ye Yang2(Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine;School of Medicine & Holistic Integrative Medicine,Nanjing University of Chinese Medicine;Department of Hematology,Affiliated Hospital of Shandong University of Traditional Chinese Medicine;Division of Hematology and Oncology,Medical College of Wisconsin;School of Pharmacy,Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University),Ministry of Education,Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong,Yantai University;Bohai Rim Advanced Research Institute for Drug Discovery).NAT10 promotes cell proliferation by acetylating CEP170 mRNA to enhance translation efficiency in multiple myeloma[J].Acta Pharmaceutica Sinica B,2022,第8期
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Zhejie Chen1,2,Wei Hao1,2,Caifang Gao1,Yangyang Zhou1,Chen Zhang3,Jinming Zhang3,Ruibing Wang1,Yitao Wang1,2,Shengpeng Wang1,2(State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau;Macau Centre for Research and Development in Chinese Medicine,University of Macau;College of Pharmacy,Chengdu University of Traditional Chinese Medicine).A polyphenol-assisted IL-10 mRNA delivery system for ulcerative colitis[J].Acta Pharmaceutica Sinica B,2022,第8期
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Honglin Tang1,2,Yanan Xue1,2,Bowen Li2,Xiaojie Xu2,Fu Zhang1,3,Jiajing Guo2,Qijun Li1,Tingting Yuan2,Yuan Chen2,Yubin Pan1,Yuan Ping2,Da Li1(Department of Medical Oncology,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University;College of Pharmaceutical Sciences,Zhejiang University;Department of Hepatobiliary and Pancreatic Surgery,the First Affiliated Hospital,Zhejiang University).Membrane-camouflaged supramolecular nanoparticles for co-delivery of chemotherapeutic and molecular-targeted drugs with siRNA against patient-derived pancreatic carcinoma[J].Acta Pharmaceutica Sinica B,2022,第8期
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Dan Liu1,2,Jianpeng Huang1,Shanshan Gao1,Hongtao Jin3,4,Jiuming He1,4(State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Clinical Pharmacy,First People's Hospital of Huaihua;New Drug Safety Evaluation Center,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College;NMPA Key Laboratory for Safety Research and Evaluation of Innovative Drug).A temporo-spatial pharmacometabolomics method to characterize pharmacokinetics and pharmacodynamics in the brain microregions by using ambient mass spectrometry imaging[J].Acta Pharmaceutica Sinica B,2022,第8期
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Sai-Qi Wang1,2,Qiu-Xu Teng3,Shuai Wang4,Zi-Ning Lei3,Hui-Hui Hu1,Hui-Fang Lv1,Bei-Bei Chen1,Jian-Zheng Wang1,Xiao-Jing Shi5,Wei-Feng Xu1,Hong-Min Liu4,2,Xiao-Bing Chen1,2,Zhe-Sheng Chen3,Bin Yu4,2(Department of Oncology,the Affiliated Cancer Hospital of Zhengzhou University,Henan Cancer Hospital,Henan Cancer Institute;State Key Laboratory of Esophageal Cancer Prevention & Treatment,Zhengzhou University;College of Pharmacy and Health Sciences,St. John's University;School of Pharmaceutical Sciences,Zhengzhou University;Laboratory Animal Center,Academy of Medical Science,Zhengzhou University).Preclinical studies of the triazolo[1,5-a]pyrimidine derivative WS-716 as a highly potent,specific and orally active P-glycoprotein(P-gp)inhibitor[J].Acta Pharmaceutica Sinica B,2022,第8期
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Minglu Zhou,Qingting Zuo,Yuan Huang,Lian Li(Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province,Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University).Immunogenic hydrogel toolkit disturbing residual tumor “seeds” and pre-metastatic “soil” for inhibition of postoperative tumor recurrence and metastasis[J].Acta Pharmaceutica Sinica B,2022,第8期
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Tingting Li1,Jie Pan2,Hongqi Chen3,Yongliang Fang4,Yang Sun2,5(Department of Gastroenterology,the Second Medical Center,National Clinical Research Center for Geriatric Diseases,State Key Laboratory of Kidney Diseases,Chinese PLA General Hospital;State Key Laboratory of Pharmaceutical Biotechnology,Department of Biotechnology and Pharmaceutical Sciences,School of Life Sciences,Nanjing University;Department of General Surgery,Shanghai Jiao Tong University Affiliated Sixth People's Hospital;Department of Urology,Boston Children's Hospital,Departments of Microbiology and Surgery,Harvard Medical School;Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy,Xuzhou Medical University).CXCR6-based immunotherapy in autoimmune,cancer and inflammatory infliction[J].Acta Pharmaceutica Sinica B,2022,第8期
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Baeksun Kim1,2,Sung Hyun Tag1,2,Eunjoo Nam3,Suji Ham1,2,Sujin Ahn3,Juhwan Kim3,Doo-Wan Cho4,Sangjoon Lee1,3,Young-Su Yang4,Seung Eun Lee5,Yong Sik Kim6,Il-Joo Cho2,7,Kwang Pyo Kim8,Su-Cheol Han4,Heh-In Im1,2,3(Convergence Research Center for Diagnosis,Treatment and Care System of Dementia (DTC),Korea Institute of Science and Technology (KIST);Division of Bio-Medical Science & Technology,KIST School,Korea University of Science and Technology (UST);Center for Neuroscience,KIST;Animal Model Research Center,Jeonbuk Department of Inhalation Research,Korea Institute of Toxicology (KIT),Korea Research Institute of Chemical Technology (KRICT);Research Animal Resource Center,KIST;Department of Pharmacology,Seoul National University College of Medicine;Center for BioMicrosystems,KIST;Department of Applied Chemistry,Kyung Hee University).SYNCRIP controls miR-137 and striatal learning in animal models of methamphetamine abstinence[J].Acta Pharmaceutica Sinica B,2022,第8期
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Yang Ge,Jun-Jie Deng,Jianzheng Zhu,Lu Liu,Shumin Ouyang,Zhendong Song,Xiaolei Zhang,Xiao-Feng Xiong(National-Local Joint Engineering Laboratory of Druggability and New Drugs Evaluation,Guangdong Province Engineering Laboratory for Druggability and New Drugs Evaluation,School of Pharmaceutical Sciences,Sun Yatsen University).Discovery of small molecule Gαq/11 protein inhibitors against uveal melanoma[J].Acta Pharmaceutica Sinica B,2022,第8期
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Cuixia Zheng1,Xinxin Liu2,1,Yueyue Kong1,Lei Zhang3,Qingling Song1,Hongjuan Zhao1,Lu Han1,Jiannan Jiao1,Qianhua Feng1,4,Lei Wang2,1,4,5(School of Pharmaceutical Sciences,Zhengzhou University;Luoyang Central Hospital Affiliated to Zhengzhou University;Department of Gynecology,the First Affiliated Hospital of Zhengzhou University;Key Laboratory of Advanced Drug Preparation Technologies,Ministry of Education,School of Pharmaceutical Sciences,Zhengzhou University;Tumor Immunity and Biomaterials Advanced Medical Center,Zhengzhou University).Hyperthermia based individual in situ recombinant vaccine enhances lymph nodes drainage for de novo antitumor immunity[J].Acta Pharmaceutica Sinica B,2022,第8期
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Wenbin Kuang1,2,Haolin Zhang1,2,Xiao Wang1,2,Peng Yang1,2(State Key Laboratory of Natural Medicines and Jiang Su Key Laboratory of Drug Design and Optimization,China Pharmaceutical University;Department of Medicinal Chemistry,School of Pharmacy,China Pharmaceutical University).Overcoming Mycobacterium tuberculosis through small molecule inhibitors to break down cell wall synthesis[J].Acta Pharmaceutica Sinica B,2022,第8期
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