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Yaqiong Jin1,Jin Shi1,2,Huanmin Wang3,Jie Lu1,Chenghao Chen4,Yongbo Yu1,Yaru Wang5,Yeran Yang1,Dong Ren1,Qi Zeng4,Xin Ni1,6,7,Yongli Guo1,7(Beijing Key Laboratory for Pediatric Diseases of Otolaryngology,Head and Neck Surgery,MOE Key Laboratory of Major Diseases in Children,Beijing Pediatric Research Institute,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health;Department of Tuberculosis,Beijing Tuberculosis and Thoracic Tumor Research Institute,Beijing Chest Hospital,Capital Medical University;Department of Surgery,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health;Department of Thoracic Surgery,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health;Department of Allergy,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health;Beijing Advanced Innovation Center for Big Data-Based Precision Medicine,Beihang University & Capital Medical University;Department of Otolaryngology,Head and Neck Surgery,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health).MYC-associated protein X binding with the variant rs72780850 in RNA helicase DEAD box 1 for susceptibility to neuroblastoma[J].Science China(Life Sciences),2021,第6期
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Jia Luo1,Shan Liang2,Feng Jin3(Department of Psychology,Sichuan Normal University;Key Laboratory of Microbial Physiological and Metabolic Engineering,Institute of Microbiology,Chinese Academy of Sciences;Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences).Gut microbiota in antiviral strategy from bats to humans:a missing link in COVID-19[J].Science China(Life Sciences),2021,第6期
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Xianran Li,Jianming Yu(Department of Agronomy,Iowa State University).Retrofitting elite cultivars with an ancestral allele for sustainable agriculture[J].Science China(Life Sciences),2021,第6期
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Fang Fang1,2,3,Hailan Hu4,5,6(School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health,Peking University;IDG/McGovern Institute for Brain Research,Peking University;Peking-Tsinghua Center for Life Sciences,Peking University;Department of Psychiatry of First Affiliated Hospital,Zhejiang University School of Medicine;The MOE Frontier Science Center for Brain Research and Brain-Machine Integration,School of Brain Science and Brain Medicine Zhejiang University;NHC and CAMS Key Laboratory of Medical Neurobiology,Mental Health Center,Zhejiang University).Recent progress on mechanisms of human cognition and brain disorders[J].Science China(Life Sciences),2021,第6期
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Encheng Sun1,Zhenjiang Zhang1,Zilong Wang1,Xijun He1,Xianfeng Zhang1,Lulu Wang1,Wenqing Wang1,Lianyu Huang1,Fei Xi1,Haoyue Huangfu1,Ghebremedhin Tsegay1,Hong Huo1,Jianhong Sun1,Zhijun Tian1,Wei Xia1,Xuewu Yu2,Fang Li1,Renqiang Liu1,Yuntao Guan1,Dongming Zhao1,Zhigao Bu1(State Key Laboratory of Veterinary Biotechnology,National High Containment Facilities for Animal Diseases Control and Prevention,Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences;College of Animal Science and Technology,Inner Mongolia University for Nationalities).Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020[J].Science China(Life Sciences),2021,第5期
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Qing Chu1,2,Dekun Bi1,2,Weiwei Zheng1,3,4,Tianjun Xu1,2,3,4(Laboratory of Fish Molecular Immunology,College of Fisheries and Life Science,Shanghai Ocean University;Laboratory of Marine Biology and Biotechnology,Qingdao Pilot National Laboratory for Marine Science and Technology;Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources,Ministry of Education,Shanghai Ocean University;National Pathogen Collection Center for Aquatic Animals,Shanghai Ocean University).MicroRNA negatively regulates NF-κB-mediated immune responses by targeting NOD1 in the teleost fish Miichthys miiuy[J].Science China(Life Sciences),2021,第5期
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Yuanfeng Sun1,Yuanhe Yang2,Xia Zhao2,Zhiyao Tang1,Shaopeng Wang1,Jingyun Fang1,2(Institute of Ecology,College of Urban and Environmental Sciences,and Key Laboratory for Earth Surface Processes of the Ministry of Education,Peking University;State Key Laboratory of Vegetation and Environmental Change,Institute of Botany,Chinese Academy of Sciences).Global patterns and climatic drivers of above-and belowground net primary productivity in grasslands[J].Science China(Life Sciences),2021,第5期
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Yanan Wang1,2,3,Fengqi Liu1,2,3,Gaochao Zhang1,2,3,Yan Su1,2,3,Xueyan Sun1,2,3,Qi Chen1,2,3,Chencong Wang1,2,3,Haixia Fu1,2,3,Yun He1,2,3,Xiaolu Zhu1,2,3,Xiao Liu1,2,3,Meng Lv1,2,3,Xiangyu Zhao1,2,3,Xiaosu Zhao1,2,3,Yueying Li4,5,Qianfei Wang4,5,6,Xiaojun Huang1,2,3,Xiaohui Zhang1,2,3(Peking University People’s Hospital,Peking University Institute of Hematology,Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation;Collaborative Innovation Centre of Hematology,Peking University;National Clinical Research Center for Hematologic Disease;CAS Key Laboratory of Genomic and Precision Medicine,Collaborative Innovation Center of Genetics and Development,Beijing Institute of Genomics,Chinese Academy of Sciences;National Center for Bioinformation;University of Chinese Academy of Sciences).Gut microbiome alterations and its link to corticosteroid resistance in immune thrombocytopenia[J].Science China(Life Sciences),2021,第5期
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Xuan Zhang1,Quancheng Wang1,Jingjun Zhao2,Xiao Li1,Wei Peng1,Zhaoxu Yang1,Zhibin Lin1,Long Yang1,Rui Ding1,Kaishan Tao1,Kefeng Dou1(Department of Hepatobiliary Surgery,Xijing Hospital,The Fourth Military Medical University;Institute of Nutrition and Food Safety,Shaanxi Provincial Center for Disease Control and Prevention).The resurgent landscape of xenotransplantation of pig organs in nonhuman primates[J].Science China(Life Sciences),2021,第5期
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Xiao Meng1,2,Ya Liu3,Chenchen Wei1,Kai Zhang1,2,Yi Zhang2,4,Ming Zhong1,Cheng Zhang1,Yun Zhang1(The Key Laboratory of Cardiovascular Remodeling and Function Research,Ministry of Education of China,Chinese National Health Commission and Chinese Academy of Medical Sciences,The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine,Department of Cardiology,Qilu Hospital,Cheeloo College of Medicine,Shandong University;Department of Infectious Disease,Renmin Hospital of Wuhan University;Department of Gastroenterology,Renmin Hospital of Wuhan University;Department of Respiratory Medicine,Qilu Hospital,Cheeloo College of Medicine,Shandong University).Angiotensin converting enzyme inhibitors and angiotensin receptor blockers improved the outcome of patients with severe COVID-19 and hypertension[J].Science China(Life Sciences),2021,第5期
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Erhui Xiong1,2,Guojun Dong3,Fei Chen1,Chen Zhang1,Shan Li1,Yanli Zhang1,Jahidul Islam Shohag4,Xiaoe Yang4,Yihua Zhou5,Qian Qian3,Limin Wu1,Yanchun Yu1(College of Life and Environmental Sciences,Hangzhou Normal University;Laboratory of Rice Biology in Henan Province,Collaborative Innovation Center of Henan Grain Crops,College of Agronomy,Henan Agricultural University;State Key Laboratory for Rice Biology,China National Rice Research Institute;Ministry of Education Key Laboratory of Environmental Remediation and Ecosystem Health,College of Environmental and Resources Science,Zhejiang University;State Key Laboratory of Plant Genomics,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences).Formyl tetrahydrofolate deformylase affects hydrogen peroxide accumulation and leaf senescence by regulating the folate status and redox homeostasis in rice[J].Science China(Life Sciences),2021,第5期
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Manlu Zhu,Haoyan Mu,Mengmei Jia,Lingfu Deng,Xiongfeng Dai(Hubei Key Laboratory of Genetic Regulation and Integrative Biology,School of Life Sciences,Central China Normal University).Control of ribosome synthesis in bacteria:the important role of rRNA chain elongation rate[J].Science China(Life Sciences),2021,第5期
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Zhenxiao Yu1,Suping Jiang1,2,Yuan Wang1,2,Xuhui Tian1,2,Pengpeng Zhao1,Jianan Xu1,Mingxia Feng1,Qunxin She1(CRISPR and Archaea Biology Research Center,State Key Laboratory of Microbial Technology,Shandong University;State Key Laboratory of Agricultural Microbiology,College of Life Science and Technology,Huazhong Agricultural University).CRISPR-Cas adaptive immune systems in Sulfolobales:genetic studies and molecular mechanisms[J].Science China(Life Sciences),2021,第5期
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Zhenxing Song1,2,Ruirui Jia1,2,Mingfeng Tang1,2,Fei Xia1,2,Haiyang Xu1,2,Zhengguo Li1,2,Chuan Huang1,2(School of Life Sciences,Chongqing University;Center of Plant Functional Genomics,Institute of Advanced Interdisciplinary Studies,Chongqing University).Antisense oligonucleotide technology can be used to investigate a circular but not linear RNA-mediated function for its encoded gene locus[J].Science China(Life Sciences),2021,第5期
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Song Lu1,2,Dianbing Wang2,Yu Hou2,3,Dongge Guo2,Yulin Deng1,Xian-En Zhang2,3(School of Life Sciences,Beijing Institute of Technology;National Laboratory of Biomacromolecules,CAS Center for Excellence in Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences;University of Chinese Academy of Sciences).Illuminating single genomic loci in live cells by reducing nuclear background fluorescence[J].Science China(Life Sciences),2021,第5期
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Ying Liu1,Hua Zhang2,Yan Cui3,Yanli Zheng4,5,Hui Chen6,Zhangli Hu1,Qingyu Wu1(College of Life Sciences and Oceanography,Shenzhen University;Shenzhen Academy of Environmental Science;Gansu Innovation Center of Microalgae Technology,Hexi University;Key Laboratory of Algal Biology,Institute of Hydrobiology,Chinese Academy of Sciences;University of the Chinese Academy of Sciences;State Key Laboratory of Crop Stress Adaptation and Improvement,School of Life Sciences,Henan University).Distinct roles of alternative oxidase pathway during the greening process of etiolated algae[J].Science China(Life Sciences),2021,第5期
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Jinbiao Sun1,2,Andrew Dixon3,Zhongru Gu1,4,Zhenzhen Lin1,Xiangjiang Zhan1,5(CAS Key Lab of Animal Ecology and Conservation Biology,Institute of Zoology,Chinese Academy of Sciences;College of Life Sciences,Henan Normal University;Reneco International Wildlife Consultants;University of Chinese Academy of Sciences;Center for Excellence in Animal Evolution and Genetics,Chinese Academy of Sciences).Status of the saker falcon in China[J].Science China(Life Sciences),2021,第5期
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Wenwen Kong1,2,Xianxin Dong3,Yongbing Ren1,2,Yuan Wang4,Xintong Xu1,Beixin Mo1,Yu Yu1,Xiaoyan Wang1(Guangdong Provincial Key Laboratory for Plant Epigenetics,Longhua Institute of Innovative Biotechnology,College of Life Sciences and Oceanography,Shenzhen University;Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province,College of Optoelectronic Engineering,Shenzhen University;Advanced Institute of Natural Sciences,Beijing Normal University at Zhuhai;State Key Laboratory of Genetic Engineering,School of Life Sciences,Fudan University).NTP4 modulates miRNA accumulation via asymmetric modification of miRNA/miRNA* duplex[J].Science China(Life Sciences),2021,第5期
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Moujian Guo1,Lixia Hui1,Yiwen Nie1,Boris Tefsen2,Ying Wu1,3(State Key Laboratory of Virology,School of Basic Medical Sciences,Wuhan University;Department of Biological Sciences,Xi’an Jiaotong-Liverpool University;Hubei Province Key Laboratory of Allergy and Immunology).ZIKV viral proteins and their roles in virus-host interactions[J].Science China(Life Sciences),2021,第5期
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Manyuan Long(Department of Ecology & Evolution,The University of Chicago).A zebrafish-specific chimeric gene evolved essential developmental functions:discussion of conceptual significance[J].Science China(Life Sciences),2021,第5期
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Xiaoyan Dai1,2,Yanli Xin1,Weizhi Xu1,Xinxia Tian2,Xiaofan Wei1,Hongquan Zhang1(Department of Human Anatomy,Histology,and Embryology,Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) and State Key Laboratory of Natural and Biomimetic Drugs,School of Basic Medical Sciences,Peking University Health Science Center;Department of Pathology,School of Basic Medical Sciences,Peking University Health Science Center).CBP-mediated Slug acetylation stabilizes Slug and promotes EMT and migration of breast cancer cells[J].Science China(Life Sciences),2021,第4期
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Wenjie Zhai1,Xiuman Zhou1,Mingxia Zhai1,Wanqiong Li2,Yunhui Ran1,Yixuan Sun1,Jiangfeng Du1,Wenshan Zhao1,Lingxiao Xing3,Yuanming Qi1,Yanfeng Gao1,2(School of Life Sciences,Zhengzhou University;School of Pharmaceutical Sciences (Shenzhen),Sun Yat-sen University;Department of Pathology,Hebei Medical University).Blocking of the PD-1/PD-L1 interaction by a novel cyclic peptide inhibitor for cancer immunotherapy[J].Science China(Life Sciences),2021,第4期
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Zhangsong Wu1,2,Jinjian Liu1,2,Ruixiang Dai1,2,Song Wu1,2,3(Department of Urological Surgery,The Third Affiliated Hospital of Shenzhen University,Shenzhen University;Shenzhen Following Precision Medical Institute,The Third Affiliated Hospital of Shenzhen University,Shenzhen University;Department of Urological Surgery,The First Affiliated Hospital of Guangzhou Medical University,Guangzhou Medical University).Current status and future perspectives of immunotherapy in bladder cancer treatment[J].Science China(Life Sciences),2021,第4期
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Chunmei Fan1,2,3,Shanshan Zhang4,Zhaojian Gong5,Xiayu Li3,Bo Xiang1,2,Hao Deng3,Ming Zhou1,2,Guiyuan Li1,2,Yong Li6,Wei Xiong1,2,Zhaoyang Zeng1,2,Xiaoling Li1,2(NHC Key Laboratory of Carcinogenesis,Hunan Cancer Hospital and the Affiliated Cancer Hospital,Xiangya School of Medicine,Central South University;Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education,Cancer Research Institute and School of Basic Medical Science,Central South University;Hunan Key Laboratory of Nonresolving Inflammation and Cancer,Disease Genome Research Center,the Third Xiangya Hospital,Central South University;Department of Stomatology,Xiangya Hospital,Central South University;Department of Oral and Maxillofacial Surgery,The Second Xiangya Hospital,Central South University;Department of Medicine,Dan L Duncan Comprehensive Cancer Center,Baylor College of Medicine).Emerging role of metabolic reprogramming in tumor immune evasion and immunotherapy[J].Science China(Life Sciences),2021,第4期
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Xuan Ma1,Chunyan Liu2,Xiaocong Kong1,Jing Liu1,Siju Zhang1,Shanshan Liang1,Weijiang Luan1,Xiaofeng Cao2(Tianjin Key Laboratory of Animal and Plant Resistance,College of Life Sciences,Tianjin Normal University;State Key Laboratory of Plant Genomics and National Center for Plant Gene Research,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences).Extensive profiling of the expressions of tRNAs and tRNA-derived fragments(tRFs) reveals the complexities of tRNA and tRF populations in plants[J].Science China(Life Sciences),2021,第4期
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Yitian Zhou1,2,Yongfa Huang2,Xiaomin Song1,Xiaoxiao Guo2,Junling Pang1,Jing Wang1,Shuyang Zhang2,Chen Wang3(State Key Laboratory of Medical Molecular Biology,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Department of Pathophysiology,Peking Union Medical College;Department of Cardiology,Peking Union Medical College Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences;State Key Laboratory of Medical Molecular Biology,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Department of Physiology,Peking Union Medical College).Single-cell transcriptional profile of ACE2 in healthy and failing human hearts[J].Science China(Life Sciences),2021,第4期
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Wenjing Yang1,2,Dandan Liu1,2,Qinghui You3,Bin Chen4,Minfei Jian3,Qiwu Hu2,Mingyang Cong5,Keping Ma6(Key Laboratory of Poyang Lake Wetland and Watershed Research (Jiangxi Normal University), Ministry of Education;School of Geography and Environment, Jiangxi Normal University;School of Life Sciences, Jiangxi Normal University;Department of Information Technology,Shanghai Chenshan Botanical Garden;Analytical & Testing Center, Jiangxi Normal University;State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences).Taxonomic bias in occurrence information of angiosperm species in China[J].Science China(Life Sciences),2021,第4期
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Qiuyu Li1,Cheng Cui2,Fei Xu3,Jianping Zhao4,Nan Li5,Haichao Li6,Tianbing Wang7,Hua Zhang5,Na Liu2,8,Yudong Wei2,Xiaoye Niu2,Yan Xu2,Jianping Dong8,Xueting Yao2,Xiaohong Wang1,Yahong Chen1,Haiyan Li2,9,Chunli Song10,Jie Qiao10,Dongyang Liu2,Ning Shen1(Department of Respiratory and Critical Care Medicine,Peking University Third Hospital;Drug Clinical Trial Center,Peking University Third Hospital;Department of Respiratory and Critical Care Medicine,the First Affiliated Hospital of Nanchang University;Department of Respiratory and Critical Care Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology;Research Center of Clinical Epidemiology,Peking University Third Hospital;Department of Respiratory and Critical Care Medicine,Peking University First Hospital;Trauma Center,Peking University People’s Hospital;Beijing Haidian Hospital,Haidian Section of Peking University Third Hospital;Department of Cardiology,Peking University Third Hospital;Institute of Medical Innovation,Peking University Third Hospital).Evaluation of the efficacy and safety of hydroxychloroquine in comparison with chloroquine in moderate and severe patients with COVID-19[J].Science China(Life Sciences),2021,第4期
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Chengwei Wu1,Haitao Shang1,Xianhong Jiang1,Xinning Wang1,Hong Wei1,2(Precision Medicine Institute,The First Affiliated Hospital,Sun Yat-sen University;College of Animal Sciences and Technology,State Key Laboratory of Agricultural Microbiology,Huazhong Agricultural University).Application of germ-free NOD-scid IL2rgnull mice as a humanized model for tumor microbiome precision medicine[J].Science China(Life Sciences),2021,第4期
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Weinan Zheng1,Liang Cui1,2,Minghui Li1,2,Yun Li1,Wenhui Fan1,Limin Yang1,Jing Li1,Lei Sun1,2,Wenjun Liu1,2,3,4(CAS Key Laboratory of Pathogenic Microbiology and Immunology,Institute of Microbiology,Chinese Academy of Sciences;University of Chinese Academy of Sciences;State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresourses & Laboratory of Animal Infectious Diseases,College of Animal Sciences and Veterinary Medicine,Guangxi University;Institute of Microbiology,Center for Biosafety Mega-Science,Chinese Academy of Sciences).Nucleoprotein phosphorylation site(Y385) mutation confers temperature sensitivity to influenza A virus due to impaired nucleoprotein oligomerization at a lower temperature[J].Science China(Life Sciences),2021,第4期
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