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Suo-wen Xu,Iqra Ilyas,Jian-ping Weng(Department of Endocrinology,Institute of Endocrine and Metabolic Diseases,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,Clinical Research Hospital of Chinese Academy of Sciences(Hefei),University of Science and Technology of China,Hefei 230001,China).Endothelial dysfunction in COVID-19:an overview of evidence,biomarkers,mechanisms and potential therapies[J].中国药理学报(英文版),2023,第4期
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Jing-xian Sun,Ke-ying Zhu,Yu-meng Wang,Dan-jie Wang,Mi-zhen Zhang,Heela Sarlus,Irene Benito-Cuesta,Xiao-qiang Zhao,Zao-feng Zou,Qing-yang Zhong,Yi Feng,Shuai Wu,Yan-qing Wang,Robert A.Harris,Jun Wang(Department of Integrative Medicine and Neurobiology,School of Basic Medical Science,Institutes of Integrative Medicine,State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Institutes of Brain Science,Shanghai Medical College,Fudan University,Shanghai 200032,China;Department of Clinical Neuroscience,Karolinska Institutet,Center for Molecular Medicine,Karolinska University Hospital at Solna,Stockholm,Sweden;Department of Integrative Medicine and Neurobiology,School of Basic Medical Science,Institutes of Integrative Medicine,State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science,Institutes of Brain Science,Shanghai Medical College,Fudan University,Shanghai 200032,China;Department of General Surgery,Jiading Hospital of Traditional Chinese Medicine,Shanghai 201800,China;Department of Neurology,Zhongshan Hospital,Fudan University,Shanghai 200032,China).Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function[J].中国药理学报(英文版),2023,第4期
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Chang-feng Song,Yu-heng Hu,Zhi-guo Mang,Zeng Ye,Hai-di Chen,De-sheng Jing,Gui-xiong Fan,Shun-rong Ji,Xian-jun Yu,Xiao-wu Xu,Yi Qin(Department of Pancreatic Surgery,Fudan University Shanghai Cancer Center,Shanghai 200032,China;Department of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China;Shanghai Pancreatic Cancer Institute,Shanghai 200032,China;Pancreatic Cancer Institute,Fudan University,Shanghai 200032,China;Yujie Biotechnology(Shanghai)Co.,Ltd.,Shanghai 201314,China).Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS\AMPK signaling pathway[J].中国药理学报(英文版),2023,第4期
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Yuan Liu,Wei-yao Kong,Cui-fu Yu,Zhen-long Shao,Qiu-cheng Lei,Yuan-fei Deng,Geng-xi Cai,Xue-fen Zhuang,Wen-shuang Sun,Shi-gang Wu,Rong Wang,Xiang Chen,Guo-xing Chen,Hong-biao Huang,Yu-ning Liao(Department of General Surgery,The Sixth Affiliated Hospital of Guangzhou Medical University,Qingyuan People's Hospital,Qingyuan 511500,China;Affiliated Cancer Hospital&Institute of Guangzhou Medical University,Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation,School of Basic Medical Sciences,Guangzhou Medical University,Guangzhou 511436,China;Affiliated Cancer Hospital&Institute of Guangzhou Medical University,Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation,School of Basic Medical Sciences,Guangzhou Medical University,Guangzhou 511436,China;Department of Hepatopancreatic Surgery,The First People's Hospital of Foshan,Foshan 528000,China;Department of Pathology,The First People's Hospital of Foshan,Foshan 528000,China;Department of Breast Surgery,The First People's Hospital of Foshan,Foshan 528000,China;Department of Pathology,The Sixth Affiliated Hospital of Guangzhou Medical University,Qingyuan People's Hospital,Qingyuan 511500,China;Department of General Surgery,The Sixth Affiliated Hospital of Guangzhou Medical University,Qingyuan People's Hospital,Qingyuan 511500,China).SNS-023 sensitizes hepatocellular carcinoma to sorafenib by inducing degradation of cancer drivers SIX1 and RPS16[J].中国药理学报(英文版),2023,第4期
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Zuo-wei Wang,Feng-ming Zou,Ao-li Wang,Jing Yang,Rui Jin,Bei-lei Wang,Li-juan Shen,Shuang Qi,Juan Liu,Jing Liu,Wen-chao Wang,Qing-song Liu(Anhui Province Key Laboratory of Medical Physics and Technology,Institute of Health and Medical Technology,Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei 230031,China;University of Science and Technology of China,Hefei 230026,China;Anhui Province Key Laboratory of Medical Physics and Technology,Institute of Health and Medical Technology,Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei 230031,China;Hefei Cancer Hospital,Chinese Academy of Sciences,Hefei 230031,China;Anhui Province Key Laboratory of Medical Physics and Technology,Institute of Health and Medical Technology,Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei 230031,China;University of Science and Technology of China,Hefei 230026,China;Hefei Cancer Hospital,Chinese Academy of Sciences,Hefei 230031,China;Precision Medicine Research Laboratory of Anhui Province,Hefei 230088,China).Repurposing of the FGFR inhibitor AZD4547 as a potent inhibitor of necroptosis by selectively targeting RIPK1[J].中国药理学报(英文版),2023,第4期
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Jian-hong Gan,Ji-xiang Liu,Yang Liu,Shu-wen Chen,Wen-tao Dai,Zhi-Xiong Xiao,Yang Cao(Center of Growth,Metabolism and Aging,Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education,College of Life Sciences,Sichuan University,Chengdu 610065,China;Center of Growth,Metabolism and Aging,Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education,College of Life Sciences,Sichuan University,Chengdu 610065,China;Shanghai Engineering Research Center of Pharmaceutical Translation,Shanghai 201203,China;Center of Growth,Metabolism and Aging,Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education,College of Life Sciences,Sichuan University,Chengdu 610065,China;State Key Laboratory of Biotherapy and Cancer Center,Sichuan University,Chengdu 610065,China;Shanghai Engineering Research Center of Pharmaceutical Translation,Shanghai 201203,China;NHC Key Lab of Reproduction Regulation(Shanghai Institute for Biomedical and Pharmaceutical Technologies),Fudan University,Shanghai 200032,China;Center of Growth,Metabolism and Aging,Key Laboratory of Bio-Resource and Eco-Environment of Ministry of Education,College of Life Sciences,Sichuan University,Chengdu 610065,China;Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province,Microbiology and Metabolic Engineering Key Laboratory of Sichuan Province,Chengdu 610065,China).DrugRep:an automatic virtual screening server for drug repurposing[J].中国药理学报(英文版),2023,第4期
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Qian Wang,Meng-wei Wang,Yan-yun Sun,Xiao-yan Hu,Pan-pan Geng,Hui Shu,Xiao-na Wang,Hao Wang,Jun-fang Zhang,Hong-qiang Cheng,Wei Wang,Xin-chun Jin(Beijing Key Laboratory of Cancer Invasion and Metastasis Research,Department of Anatomy,Histology and Embryology,School of Basic Medical Sciences,Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing 100069,China;Institute of Neuroscience,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China;School of Medicine,Ningbo University,Ningbo 315211,China;Zhejiang Provincial Key Laboratory of Pathophysiology,Ningbo 315211,China;Department of Pathology and Pathophysiology,Zhejiang University School of Medicine,Hangzhou 310058,China;Department of Physiology and Pathophysiology,Capital Medical University,Beijing 100069,China;Beijing Key Laboratory of Cancer Invasion and Metastasis Research,Department of Anatomy,Histology and Embryology,School of Basic Medical Sciences,Advanced Innovation Center for Human Brain Protection,Capital Medical University,Beijing 100069,China;Institute of Neuroscience,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China).Nicotine pretreatment alleviates MK-801-induced behavioral and cognitive deficits in mice by regulating Pdlim5\CRTC1 in the PFC[J].中国药理学报(英文版),2023,第4期
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Shi-qi Huang,Han-ming Zhang,Yi-cong Zhang,Lu-yao Wang,Zhi-rong Zhang,Ling Zhang(Key Laboratory of Drug Targeting and Drug Delivery Systems,Ministry of Education,West China School of Pharmacy;College of Polymer Science and Engineering;Med-X Center for Materials,Sichuan University,Chengdu 610041,China).Comparison of two methods for tumour-targeting peptide modification of liposomes[J].中国药理学报(英文版),2023,第4期
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Lei Li,Jing-jing Song,Meng-xue Zhang,Hui-wen Zhang,Hai-yan Zhu,Wei Guo,Cai-long Pan,Xue Liu,Lu Xu,Zhi-yuan Zhang(School of Basic Medical Sciences,Nanjing Medical University,Nanjing 211166,China;Department of Urology,The Affiliated Wuxi No.2 People's Hospital of Nanjing Medical University,Wuxi 214002,China;School of Basic Medical Sciences,Nanjing Medical University,Nanjing 211166,China;Key Laboratory of Antibody Technique of Ministry of Health,Nanjing Medical University,Nanjing 211166,China;School of Basic Medical Sciences,Nanjing Medical University,Nanjing 211166,China;Department of Neurology,Sir Run Run Hospital,Nanjing Medical University,Nanjing 211166,China).Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy[J].中国药理学报(英文版),2023,第4期
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Qian-qian Wang,Liaqat Hussain,Pei-han Yu,Chang Yang,Chen-ying Zhu,Ya-fang Ma,Si-chun Wang,Tao Yang,Yuan-yuan Kang,Wen-juan Yu,Yasen Maimaitiyiming,Hua Naranmandura(Department of Hematology of First Affiliated Hospital,and Department of Public Health,Zhejiang University School of Medicine,Hangzhou 310003,China;Zhejiang Province Key Laboratory of Haematology Oncology Diagnosis and Treatment,Hangzhou 310003,China;Cancer Center,Zhejiang University,Hangzhou 310058,China;Faculty of Pharmaceutical Sciences,Government College University,Faisalabad 38000,Pakistan;Department of Hematology of First Affiliated Hospital,and Department of Public Health,Zhejiang University School of Medicine,Hangzhou 310003,China;Department of Hematology,First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310003,China;Department of Hematology of First Affiliated Hospital,and Department of Public Health,Zhejiang University School of Medicine,Hangzhou 310003,China;Department of Neurobiology,NHC and CAMS Key Laboratory of Medical Neurobiology,School of Brain Science and Brain Medicine,and MOE Frontier Science Center for Brain Science and Brain-machine Integration,Zhejiang University School of Medicine,Hangzhou 310031,China).Hyperthermia promotes degradation of the acute promyelocytic leukemia driver oncoprotein ZBTB16\RARα[J].中国药理学报(英文版),2023,第4期
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Zhan Xie,Xin-jing Wu,Rui-wen Cheng,Jia-hua Cui,Song-tao Yuan,Jian-wei Zhou,Qing-huai Liu(Department of Ophthalmology,First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China;Department of Molecular Cell Biology&Toxicology,Center for Global Health,School of Public Health,Nanjing Medical University,Nanjing 211166,China).JP1,a polypeptide specifically targeting integrin αVβ3,ameliorates choroidal neovascularization and diabetic retinopathy in mice[J].中国药理学报(英文版),2023,第4期
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Yeojin Bang,Yoonjung Kwon,Mihyang Kim,Soung Hee Moon,Kiwon Jung,Hyun Jin Choi(College of Pharmacy and Institute of Pharmaceutical Sciences,CHA University,Pocheon,Gyeonggi-do 11160,South Korea).Ursolic acid enhances autophagic clearance and ameliorates motor and non-motor symptoms in Parkinson’s disease mice model[J].中国药理学报(英文版),2023,第4期
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Yan Chen,Chen-yao Wang,Gui-ying Zan,Song-yu Yao,Ying-zhi Deng,Xue-lian Shu,Wei-wei Wu,Yan Ma,Yu-jun Wang,Chang-xi Yu,Jing-gen Liu(Department of Pharmacology;CAS Key Laboratory of Receptor Research and State Key Laboratory of Drug Research;University of Chinese Academy of Sciences;School of Chinese Materia Medica).Upregulation of dynorphin/kappa opioid receptor system in the dorsal hippocampus contributes to morphine withdrawal-induced place aversion[J].中国药理学报(英文版),2023,第3期
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Su-ling Huang,Wei Xie,Yang-liang Ye,Jia Liu,Hui Qu,Yu Shen,Ti-fei Xu,Zhuo-hui Zhao,Yu Shi,Jian-hua Shen,Ying Leng(State Key Laboratory of Drug Research;University of Chinese Academy of Sciences;Shanghai Institute of Materia Medica).Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice[J].中国药理学报(英文版),2023,第3期
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Xiao-yu He,Meng-meng Zhu,Juan Zheng,Cheng-yi Wang,Xiao-kang Zhao,Bao-tong Zhang,Da-chen Zhou,Shuang Zhang,Xiao-xiao Yang,Ya-jun Duan,Ji-hong Han,Yuan-li Chen(Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes;Department of Human Cell Biology and Genetics;Department of General Surgery;College of Life Sciences).Liver X receptor agonists exert antitumor effects against hepatocellular carcinoma via inducing REPS2 expression[J].中国药理学报(英文版),2023,第3期
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Wen-fang Li,Leader Alfason,Can Huang,Yu Tang,Li Qiu,Makoto Miyagishi,Shou-rong Wu,Vivi Kasim(Key Laboratory of Biorheological Science and Technology;The 111 Project Laboratory of Biomechanics and Tissue Repair;Department of Biochemistry and Molecular Biology;Molecular Composite Medicine Research Group;Chongqing Key Laboratory of Translational Research for Cancer Metastasis and Individualized Treatment).p52-ZER6:a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors[J].中国药理学报(英文版),2023,第3期
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Yang Hong,Wan-qing Xu,Jing Feng,Han Lou,Heng Liu,Lei Wang,Hao Cui,Lin-tong Jiang,Ran-chen Xu,Heng-hui Xu,Min-zhen Xie,Yang Li,Philipp Kopylov,Qi Wang,Yong Zhang(Department of Pharmacology(the State-Province Key Laboratories of Biomedicine Pharmaceutics of China;Department of Medicinal Chemistry and Natural Medicinal Chemistry;Department of Pharmaceutical Analysis;Department of Preventive and Emergency Cardiology;Research Unit of Noninfectious Chronic Diseases in Frigid Zone;Institute of Metabolic Disease).Nitidine chloride induces cardiac hypertrophy in mice by targeting autophagy-related 4B cysteine peptidase[J].中国药理学报(英文版),2023,第3期
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Wei Liu,Shi-ou Zhu,Yu-lin Guo,Long-fang Tu,Yong-qi Zhen,Rong-yan Zhao,Liang Ou-Yang,Hiroshi Kurihara,Rong-Rong He,Bo Liu(State Key Laboratory of Biotherapy and Cancer Center;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research;Guangdong Engineering Research Center of Chinese Medicine&Disease Susceptibility).BL-918,a small-molecule activator of ULK1,induces cytoprotective autophagy for amyotrophic lateral sclerosis therapy[J].中国药理学报(英文版),2023,第3期
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Jin-kang Shen,Hai-tao Zhang(Hangzhou Institute of Innovative Medicine;The Second Affiliated Hospital).Function and structure of bradykinin receptor 2 for drug discovery[J].中国药理学报(英文版),2023,第3期
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Lu Zhang,Xian-meng Li,Xu-he Shi,Kai Ye,Xue-li Fu,Xue Wang,Shi-man Guo,Jia-qi Ma,Fei-fei Xu,Hui-min Sun,Qian-qian Li,Wei-ying Zhang,Li-hong Ye(State Key Laboratory of Medicinal Chemical Biology).Sorafenib triggers ferroptosis via inhibition of HBXIP/SCD axis in hepatocellular carcinoma[J].中国药理学报(英文版),2023,第3期
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Shu-na Wang,Zhi Wang,Xi-yuan Wang,Xiu-ping Zhang,Tian-ying Xu,Chao-yu Miao(Department of Pharmacology;Department of Anesthesia Pharmacology).Humanized cerebral organoids-based ischemic stroke model for discovering of potential anti-stroke agents[J].中国药理学报(英文版),2023,第3期
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Yi-fan Chen,Run-zhi Liu,Wen-wen Ying,Yue-ning Yang,Sen-feng Xiang,Xue-jing Shao,Ji Cao,Yan-qi Zhang,Bo Yang,Qiao-jun He,Mei-dan Ying(Institute of Pharmacology and Toxicology;Cancer Center;Innovation Institute for Artificial Intelligence in Medicine;Department of Pharmacy;Children’s Hospital).Arctigenin impairs UBC12 enzyme activity and cullin neddylation to attenuate cancer cells[J].中国药理学报(英文版),2023,第3期
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Xiao-liang Dong,Bao-hui Yuan,Sheng-zhou Yu,He Liu,Xiao-hua Pan,Jia Sun,Li-long Pan(Wuxi School of Medicine;School of Food Science and Technology;State Key Laboratory of Food Science and Technology).Adriamycin induces cardiac fibrosis in mice via PRMT5-mediated cardiac fibroblast activation[J].中国药理学报(英文版),2023,第3期
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Jie Li,Yan Zhou,Guy Eelen,Qing-tong Zhou,Wen-bo Feng,Viktorija Labroska,Fen-fen Ma,Hui-ping Lu,Mieke Dewerchin,Peter Carmeliet,Ming-wei Wang,De-hua Yang(Department of Pharmacology;The National Center for Drug Screening;Laboratory of Angiogenesis and Vascular Metabolism;University of Chinese Academy of Sciences;Department of Pharmacy;Research Center for Deepsea Bioresources;Department of Chemistry).A high-throughput screening campaign against PFKFB3 identified potential inhibitors with novel scaffolds[J].中国药理学报(英文版),2023,第3期
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Ni Jiayun,Wang Xin,Xie Hongyan,Yang Ninghao,Li Jingyao,Sun Xiang,Guo Hengjiang,Zhou Li,Zhang Wei,Liu Jun,Lu Limin.Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-beta receptor II[J].中国药理学报,2023,第3期
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Sun-li Hu,Abdullah Al Mamun,Jian Shaw,Sun-long Li,Yi-feng Shi,Xue-man Jin,Ying-xin Yu,Chao-zhi Pang,Ze-yang Li,Jia-jie Lu,Yue-piao Cai,Xiang-yang Wang,Jian Xiao(Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine;Molecular Pharmacology Research Center;The Second School of Medicine).TBK1-medicated DRP1 phosphorylation orchestrates mitochondrial dynamics and autophagy activation in osteoarthritis[J].中国药理学报(英文版),2023,第3期
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Bing-tian Xu,Meng-fan Li,Ke-chun Chen,Xing Li,Ning-bo Cai,Jiang-ping Xu,Hai-tao Wang(Guangdong Provincial Key Laboratory of New Drug Screening;Department of Neurology;Key Laboratory of Mental Health of the Ministry of Education;Center for Brain Science and Brain-Inspired Intelligence).Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats[J].中国药理学报(英文版),2023,第3期
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Ze-yu Li,Guo-qing Lu,Jing Lu,Pan-xia Wang,Xiao-lei Zhang,Yong Zou,Pei-qing Liu(National-Local Joint Engineering Laboratory of Druggability and New Drugs Evaluation;School of Pharmaceutical Sciences).SZC-6,a small-molecule activator of SIRT3,attenuates cardiac hypertrophy in mice[J].中国药理学报(英文版),2023,第3期
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Jia-yun Ni,Xin Wang,Hong-yan Xie,Ning-hao Yang,Jing-yao Li,Xi-ang Sun,Heng-jiang Guo,Li Zhou,Wei Zhang,Jun Liu,Li-min Lu(Department of Physiology and Pathophysiology;Shanghai Key Laboratory of Kidney and Blood Purification).Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-βreceptor II[J].中国药理学报(英文版),2023,第3期
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Munki Choo,Van-Hieu Mai,Han Sun Kim,Dong-Hwa Kim,Ja-Lok Ku,Sang Kook Lee,Chul‐Kee Park,Yong Jin An,Sunghyouk Park(Natural Product Research Institute;Korean Cell Line Bank;Department of Neurosurgery).Involvement of cell shape and lipid metabolism in glioblastoma resistance to temozolomide[J].中国药理学报(英文版),2023,第3期
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