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Pengcheng Wang,Guangyi Zeng,Yu Yan,Song-yang Zhang,Yongqiang Dong,Yangming Zhang,Xingzhong Zhang,Huiying Liu,Zhipeng Zhang,Changtao Jiang,Yanli Pang(Department of Physiology and Pathophysiology;Center of Basic Medical Research;Center for Reproductive Medicine;Center for Obesity and Metabolic Disease Research;General Surgery Department).Disruption of adipocyte HIF-1α improves atherosclerosis through the inhibition of ceramide generation[J].药学学报:英文版,2022,第4期
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Lei Feng,Xiangge Tian,Dahong Yao,Zhenlong Yu,Xiaokui Huo,Zhenhao Tian,Jing Ning,Jingnan Cui,Tony D.James,Xiaochi Ma(Second Affiliated Hospital;College of Pharmacy;School of Pharmaceutical Sciences;State Key Laboratory of Fine Chemicals;Department of Chemistry;School of Chemistry and Chemical Engineering).A practical strategy to develop isoform-selective near-infrared fluorescent probes for human cytochrome P450 enzymes[J].药学学报:英文版,2022,第4期
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Lingxin Hou,Ying Zhang,Han Ju,Srinivasulu Cherukupalli,Ruifang Jia,Jian Zhang,Bing Huang,Arianna Loregian,Xinyong Liu,Peng Zhan(Department of Medicinal Chemistry;Institute of Poultry Science;Department of Molecular Medicine;China-Belgium Collaborative Research Center for Innovative Antiviral Drugs of Shandong Province;Institute of Medical Sciences).Contemporary medicinal chemistry strategies for the discovery and optimization of influenza inhibitors targeting vRNP constituent proteins[J].药学学报:英文版,2022,第4期
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Chunlong Ma,Haozhou Tan,Juliana Choza,Yuyin Wang,Jun Wang(Department of Pharmacology and Toxicology).Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays[J].药学学报:英文版,2022,第4期
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Jie Zhou,Wei Xu,Zezhong Liu,Chao Wang,Shuai Xia,Qiaoshuai Lan,Yanxing Cai,Shan Su,Jing Pu,Lixiao Xing,Youhua Xie,Lu Lu,Shibo Jiang,Qian Wang(Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS);State Key Laboratory of Toxicology and Medical Countermeasures).A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases[J].药学学报:英文版,2022,第4期
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Chuanbin Yang,Chengfu Su,Ashok Iyaswamy,Senthil Kumar Krishnamoorthi,Zhou Zhu,Sichang Yang,Benjamin Chunkit Tong,Jia Liu,Sravan G.Sreenivasmurthy,Xinjie Guan,Yuxuan Kan,Aston Jiaxi Wu,Alexis Shiying Huang,Jieqiong Tan,Kingho Cheung,Juxian Song,Min Li(Mr.&Mrs.Ko Chi-Ming Centre for Parkinson’s Disease Research;Department of Geriatrics;Institute for Research and Continuing Education;College of Pharmacy;Center for Medical Genetics and Hunan Key Laboratory of Animal Model for Human Diseases;Medical College of Acupuncture-Moxibustion and Rehabilitation).Celastrol enhances transcription factor EB (TFEB)-mediated autophagy and mitigates Tau pathology:Implications for Alzheimer's disease therapy[J].药学学报:英文版,2022,第4期
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Minsong Guo,Fengdan Zhu,Wenqiao Qiu,Gan Qiao,Betty Yuen-Kwan Law,Lu Yu,Jianming Wu,Yong Tang,Chonglin Yu,Dalian Qin,Xiaogang Zhou,Anguo Wu(Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation;State Key Laboratory of Quality Research in Chinese Medicine;Department of Neurosurgery Sichuan Provincial People’s Hospital).High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS[J].药学学报:英文版,2022,第4期
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Minyang Fu,Dandan Peng,Tianxia Lan,Yuquan Wei,Xiawei Wei(Laboratory of Aging Research and Cancer Drug Target).Multifunctional regulatory protein connective tissue growth factor (CTGF):A potential therapeutic target for diverse diseases[J].药学学报:英文版,2022,第4期
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Tiecheng Zhong,Wenxin Zhang,Hongjie Guo,Xiaohui Pan,Xi Chen,Qiaojun He,Bo Yang,Ling Ding(Zhejiang Province Key Laboratory of Anti-Cancer Drug Research).The regulatory and modulatory roles of TRP family channels in malignant tumors and relevant therapeutic strategies[J].药学学报:英文版,2022,第4期
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Hui Liu,Weimin Qiu,Tianyu Sun,Lei Wang,Chenxi Du,Yanyu Hu,Wenyuan Liu,Feng Feng,Yao Chen,Haopeng Sun(School of Pharmacy;School of Pharmacy;Jiangsu Drug Development Engineering Research Center for Central Degenerative Disease;Department of Natural Medicinal Chemistry;Department of Pharmaceutical Analysis).Therapeutic strategies of glioblastoma (GBM):The current advances in the molecular targets and bioactive small molecule compounds[J].药学学报:英文版,2022,第4期
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Jun Wang,Yanmei Hu,Madeleine Zheng(Department of Pharmacology and Toxicology).Enterovirus A71 antivirals:Past,present,and future[J].药学学报:英文版,2022,第4期
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Mengqi Xu,Cong Mao,Haoting Chen,Lu Liu,Yabin Wang,Abid Hussain,Sulei Li,Xu Zhang,Ruslan G.Tuguntaev,Xing-Jie Liang,Weisheng Guo,Feng Cao(Department of Cardiology;Department of Minimally Invasive Interventional Radiology;Laboratory of Controllable Nanopharmaceuticals;Department of Urology).Osteopontin targeted theranostic nanoprobes for laser-induced synergistic regression of vulnerable atherosclerotic plaques[J].药学学报:英文版,2022,第4期
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Yongrong Yao,Huachao Chen,Ninghua Tan(State Key Laboratory of Natural Medicines).Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy[J].药学学报:英文版,2022,第4期
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Zhiqiang Deng,Yu Dong,Xiaoting Zhou,Jia-Hong Lu,Zhenyu Yue(State Key Laboratory of Quality Research in Chinese Medicine;Department of Neurology;Department of Geriatrics).Pharmacological modulation of autophagy for Alzheimer's disease therapy:Opportunities and obstacles[J].药学学报:英文版,2022,第4期
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Guangdi Li,Yali Wang,Erik De Clercq(Hunan Provincial Key Laboratory of Clinical Epidemiology;Rega Institute for Medical Research).Approved HIV reverse transcriptase inhibitors in the past decade[J].药学学报:英文版,2022,第4期
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Zhiwei Zhang,Suling Ding,Zhe Wang,Xiaowei Zhu,Zheliang Zhou,Weiwei Zhang,Xiangdong Yang,Junbo Ge(Institutes of Biomedical Sciences and Shanghai Institute of Cardiovascular Diseases;Reproductive Medicine Centre;Department of Cardiology;NHC Key Laboratory of Viral Heart Diseases;Key Laboratory of Viral Heart Diseases).Prmt1 upregulated by Hdc deficiency aggravates acute myocardial infarction via NETosis[J].药学学报:英文版,2022,第4期
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Hong Wang,Qianqian Wang,Guodi Cai,Zhijian Duan,Zoann Nugent,Jie Huang,Jianwei Zheng,Alexander D.Borowsky,Jian Jian Li,Peiqing Liu,Hsing-Jien Kung,Leigh Murphy,Hong-Wu Chen,Junjian Wang(School of Pharmaceutical Sciences;Department of Biochemistry and Molecular Medicine;Research Institute in Oncology and Hematology;Guangdong Lung Cancer Institute;Department of Pathology and Laboratory Medicine;Department of Radiation Oncology;National-Local Joint Engineering Laboratory of Druggability and New Drugs Evaluation;UC Davis Comprehensive Cancer Center).Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance[J].药学学报:英文版,2022,第4期
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Shuai Guo,Kening Li,Yanwen Chen,Bin Li(State Key Laboratory of Natural Medicines and School of Traditional Chinese Pharmacy).Unraveling the drug distribution in brain enabled by MALDI MS imaging with laser-assisted chemical transfer[J].药学学报:英文版,2022,第4期
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Tengfei Xue,Juan Ji,Yuqin Sun,Xinxin Huang,Zhenyu Cai,Jin Yang,Wei Guo,Ruobing Guo,Hong Cheng,Xiulan Sun(Department of Pharmacology;Nanjing University of Chinese Medicine;The First Affiliated Hospital of Nanjing Medical University).Sphingosine-1-phosphate,a novel TREM2 ligand,promotes microglial phagocytosis to protect against ischemic brain injury[J].药学学报:英文版,2022,第4期
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Hsiang-i Tsai,Yanping Wu,Rui Huang,Dandan Su,Yingyi Wu,Xiaoyan Liu,Linglu Wang,Zhanxue Xu,Yuxin Pang,Chong Sun,Chao He,Fan Shu,Haitao Zhu,Dongqing Wang,Fang Cheng,Laiqiang Huang,Hongbo Chen(School of Pharmaceutical Sciences(Shenzhen);Department of Medical Imaging;Department of Hematology;The Shenzhen Key Lab of Gene and Antibody Therapy;School of Traditional Medicine Materials Resource;Immune Regulation in Cancer).PHF6 functions as a tumor suppressor by recruiting methyltransferase SUV39H1 to nucleolar region and offers a novel therapeutic target for PHF6-muntant leukemia[J].药学学报:英文版,2022,第4期
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Wen-Xing Ding,Russell H.Swerdlow(Department of Pharmacology;Department of Neurology).Editorial of special column on Drug targets and drug development for Alzheimer's disease[J].药学学报:英文版,2022,第4期
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Zhidi Pan,Jie Chen,Xiaodong Xiao,Yueqing Xie,Hua Jiang,Baohong Zhang,Huili Lu,Yunsheng Yuan,Lei Han,Yuexian Zhou,Huifang Zong,Lei Wang,Rui Sun,Jianwei Zhu(Engineering Research Center of Cell&Therapeutic Antibody;Jecho Laboratories;Jecho Biopharmaceuticals Co.).Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement[J].药学学报:英文版,2022,第4期
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Zhiwei Xiao,Huiyi Wei,Yi Xu,Ahmed Haider,Junjie Wei,Shiyu Yuan,Jian Rong,Chunyu Zhao,Guocong Li,Weibin Zhang,Huangcan Chen,Yuefeng Li,Lingling Zhang,Jiyun Sun,Shaojuan Zhang,Hai-Bin Luo,Sen Yan,Qijun Cai,Lu Hou,Chao Che,Steven H.Liang,Lu Wang(Center of Cyclotron and PET Radiopharmaceuticals;Division of Nuclear Medicine and Molecular Imaging;Department of Cardiology;State Key Laboratory of Chemical Oncogenomics;Guangdong Landau Biotechnology Co.Ltd.;Key Laboratory of Tropical Biological Resources of Ministry of Education;Guangdong-Hongkong-Macao Institute of CNS Regeneration).Discovery of a highly specific 18F-labeled PET ligand for phosphodiesterase 10A enabled by novel spirocyclic iodonium ylide radiofluorination[J].药学学报:英文版,2022,第4期
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Xueqin He,Xiaorong Wang,Lianyi Yang,Zhihang Yang,Wenqi Yu,Yazhen Wang,Rui Liu,Meiwan Chen,Huile Gao(Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province;State Key Laboratory of Quality Research in Chinese Medicine).Intelligent lesion blood–brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection[J].药学学报:英文版,2022,第4期
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Zhong Li,Jimin Xu,Yuekun Lang,Xiangmeng Wu,Saiyang Hu,Subodh Kumar Samrat,Anil M.Tharappel,Lili Kuo,David Butler,Yongcheng Song,Qing-Yu Zhang,Jia Zhou,Hongmin Li(Department of Pharmacology and Toxicology;Wadsworth Center;Chemical Biology Program;The Neural Stem Cell Institute;Department of Pharmacology and Chemical Biology).In vitro and in vivo characterization of erythrosin B and derivatives against Zika virus[J].药学学报:英文版,2022,第4期
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Sameera Senaweera,Tiffany C.Edwards,Jayakanth Kankanala,Yan Wang,Rajkumar Lalji Sahani,Jiashu Xie,Robert J.Geraghty,Zhengqiang Wang(Center for Drug Design;Translational Medicine R&D Center).Discovery of N-benzyl hydroxypyridone carboxamides as a novel and potent antiviral chemotype against human cytomegalovirus (HCMV)[J].药学学报:英文版,2022,第4期
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Yunlong Shan,Qi Ni,Qixiang Zhang,Mengying Zhang,Bin Wei,Lingge Cheng,Chongjin Zhong,Xinyu Wang,Qingqing Wang,Jiali Liu,Jingwei Zhang,Jingjing Wu,Guangji Wang,Fang Zhou(Key Laboratory of Drug Metabolism and Pharmacokinetics;Department of Hematology and Oncology).Targeting tumor endothelial hyperglycolysis enhances immunotherapy through remodeling tumor microenvironment[J].药学学报:英文版,2022,第4期
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Saba R.Aliyari,Amir Ali Ghaffari,Olivier Pernet,Kislay Parvatiyar,Yao Wang,Hoda Gerami,Ann-Jay Tong,Laurent Vergnes,Armin Takallou,Adel Zhang,Xiaochao Wei,Linda D.Chilin,Yuntao Wu,Clay F.Semenkovich,Karen Reue,Stephen T.Smale,Benhur Lee,Genhong Cheng(Department of Microbiology;EnViro International Laboratories;Department of Human Genetics;Division of Endocrinology;Center for Infectious Disease Research;Diabetic Cardiovascular Disease Center).Suppressing fatty acid synthase by type I interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2[J].药学学报:英文版,2022,第4期
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Jun Wang,Hongmin Li(Department of Medicinal Chemistry;Department of Pharmacology and Toxicology).Editorial of Special Column on Antiviral Drug Discovery and Pharmacology[J].药学学报:英文版,2022,第4期
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