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期刊文章列表

  • Shipeng He1,Junhui Ma2,Yuxin Fang2,Ying Liu1,Shanchao Wu2,Guoqiang Dong2,Wei Wang3,Chunquan Sheng2,4(Institute of Translational Medicine,Shanghai University;School of Pharmacy,Second Military Medical University;Department of Pharmacology and Toxicology and BIO5 Institute,University of Arizona;School of Medicine,Tongji University).Homo-PROTAC mediated suicide of MDM2 to treat non-small cell lung cancer[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Hong Zhang,Liwu Fu(State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Guangdong Esophageal Cancer Institute,Sun Yat-sen University Cancer Center).The role of ALDH2 in tumorigenesis and tumor progression:Targeting ALDH2 as a potential cancer treatment[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Xiaojun Song1,Jianming Lv2,Zhiqin Cao2,Huiyun Huang2,Guodong Chen2,Takayoshi Awakawa3,Dan Hu2,Hao Gao1,2,Ikuro Abe3,Xinsheng Yao1,2(College of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University;Institute of Traditional Chinese Medicine and Natural Products,College of Pharmacy,Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research,Jinan University;Graduate School of Pharmaceutical Sciences,the University of Tokyo).Extensive expansion of the chemical diversity of fusidane-type antibiotics using a stochastic combinational strategy[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Michael A.Serwetnyk,Brian S.J.Blagg(Department of Chemistry and Biochemistry,Warren Family Research Center for Drug Discovery and Development,University of Notre Dame).The disruption of protein-protein interactions with co-chaperones and client substrates as a strategy towards Hsp90 inhibition[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Yani Liu1,2,Zongtao Liu3,KeWei Wang1,2(Department of Pharmacology,School of Pharmacy,Qingdao University Medical College;Institute of Innovative Drugs,Qingdao University;Department of Clinical Laboratory,Qingdao Third People's Hospital).The Ca2+-activated chloride channel ANO1/TMEM16A:An emerging therapeutic target for epithelium-originated diseases?[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Xiaoxiao Yang1,Wen Lu1,Christopher P.Hopper1,2,Bowen Ke3,Binghe Wang1(Department of Chemistry and Center for Diagnostics and Therapeutics,Georgia State University;Institut für Experimentelle Biomedizin,Universit?tsklinikum Würzburg;Department of Anesthesiology,West China Hospital).Nature’s marvels endowed in gaseous molecules Ⅰ:Carbon monoxide and its physiological and therapeutic roles[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Ying Wang1,Jiaojiao Zhang1,Xinyu Cao2,Yaya Guan1,Shuang Shen2,Genshen Zhong1,Xiwen Xiong3,Yanhong Xu2,Xiaoying Zhang2,Hui Wang1,Jianping Ye2,4(Henan Key Laboratory of Immunology and Targeted Therapy,Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine,School of Laboratory Medicine,Xinxiang Medical University;Shanghai Diabetes Institute,Shanghai Jiao Tong University Affiliated Sixth People's Hospital;School of Forensic Medicine,Xinxiang Medical University;Central Laboratory,Shanghai Sixth People's Hospital East Campus,Shanghai Jiao Tong University).Mitochondrial protein IF1 is a potential regulator of glucagon-like peptide(GLP-1) secretion function of the mouse intestine[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Jiashu Xie,Zhengqiang Wang(Center for Drug Design,College of Pharmacy,University of Minnesota).Can remdesivir and its parent nucleoside GS-441524 be potential oral drugs? An in vitro and in vivo DMPK assessment[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Tran Thi Van Anh1,2,Alilou Mostafa1,Zhigang Rao3,Simona Pace4,Stefan Schwaiger1,Christian Kretzer4,Veronika Temml1,5,Carsten Giesel4,Paul M.Jordan4,Rossella Bilancia6,Christina Weinigel7,Silke Rummler7,Birgit Waltenberger1,Tran Hung2,Antonietta Rossi6,Hermann Stuppner1,Oliver Werz4,Andreas Koeberle3,4(Institute of Pharmacy,Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI),University of Innsbruck;Faculty of Pharmacy,University of Medicine and Pharmacy at Ho Chi Minh City;Michael Popp Institute and Center for Molecular Biosciences Innsbruck (CMBI),University of Innsbruck;Department of Pharmaceutical,Medicinal Chemistry,Institute of Pharmacy,Friedrich Schiller University Jena;Institute of Pharmacy,Department of Pharmaceutical and Medicinal Chemistry,Paracelsus Medical University Salzburg;Department of Pharmacy,School of Medicine,University of Naples Federico Ⅱ;Institute of Transfusion Medicine,University Hospital Jena).From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Lihua Su1,2,Xintian Zhang1,2,Yunbao Ma1,Changan Geng1,Xiaoyan Huang1,Jing Hu1,Tianze Li1,Shuang Tang1,2,Cheng Shen1,2,Zhen Gao1,2,Xuemei Zhang1,Ji-Jun Chen1,2(State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Yunnan Key Laboratory of Natural Medicinal Chemistry;University of Chinese Academy of Sciences).New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Zhen Chen1,Wakana Mori2,Jian Rong1,Michael A.Schafroth3,Tuo Shao1,Richard S.Van4,Daisuke Ogasawara3,Tomoteru Yamasaki2,Atsuto Hiraishi2,Akiko Hatori2,Jiahui Chen1,Yiding Zhang2,Kuan Hu2,Masayuki Fujinaga2,Jiyun Sun1,Qingzhen Yu1,Thomas L.Collier1,Yihan Shao4,Benjamin F.Cravatt3,Lee Josephson1,Ming-Rong Zhang2,Steven H.Liang1(Division of Nuclear Medicine and Molecular Imaging,Massachusetts General Hospital & Department of Radiology,Harvard Medical School;Department of Advanced Nuclear Medicine Sciences,National Institute of Radiological Sciences,National Institutes for Quantum and Radiological Science and Technology;The Skaggs Institute for Chemical Biology and Department of Chemical Physiology,The Scripps Research Institute;Department of Chemistry and Biochemistry,University of Oklahoma).Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Zhiqiang Wang1,Zhibo Zhang1,Yong Li2,Li Sun1,Dezhen Peng1,Danyu Du1,Xian Zhang3,Luwei Han3,Liwen Zhao3,Ligong Lu2,Hongzhi Du4,Shengtao Yuan1,Meixiao Zhan2(Jiangsu Key Laboratory of Drug Screening,China Pharmaceutical University;Zhuhai Interventional Medical Center,Zhuhai Precision Medical Center,Zhuhai People's Hospital,Zhuhai Hospital Affiliated with Jinan University,Jinan University;Sanhome Pharmaceutical Co.,Ltd.;School of Pharmacy,Hubei University of Chinese Medicine).Preclinical efficacy against acute myeloid leukaemia of SH1573, a novel mutant IDH2 inhibitor approved for clinical trials in China[J].Acta Pharmaceutica Sinica B,2021,第6期
  • David Dahlgren1,Tobias Olander1,Markus Sj?blom2,Mikael Hedeland3,4,Hans Lennern?s1(Department of Pharmaceutical Biosciences,Translational Drug Discovery and Development,Uppsala University Department of Neuroscience,Division of Physiology,Uppsala University Department of Medicinal Chemistry,Analytical Pharmaceutical Chemistry,Uppsala University Department of Chemistry,Environment and Feed Hygiene,National Veterinary Institute (SVA)).Effect of paracellular permeation enhancers on intestinal permeability of two peptide drugs,enalaprilat and hexarelin, in rats[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Jian-dong Jiang(APSB).Celebratory message from the Editor-in-Chief on the 10th anniversary of APSB[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Xinxin Ding(APSB).A message from the Co-Editor-in-Chief[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Editoral Office of Acta Pharmaceutica Sinica(Editoral Office of Acta Pharmaceutica Sinica).Information for Authors[J].Acta Pharmaceutica Sinica B,2021,第6期
  • Yanan He1,Wei Huang1,Chen Zhang1,Lumeng Chen1,Runchun Xu1,Nan Li1,Fang Wang2,Li Han3,Ming Yang2,Dingkun Zhang1(State Key Laboratory Breeding Base of Systematic Research,Development and Utilization of Chinese Medicine Resources,Chengdu University of Traditional Chinese Medicine;Jiangxi University of Traditional Chinese Medicine;The College of Pharmacy,Chengdu University of Traditional Chinese Medicine).Energy metabolism disorders and potential therapeutic drugs in heart failure[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Airong Li,Chenglin Liang,Lihua Xu,Yiyang Wang,Wei Liu,Kaixiang Zhang,Junjie Liu,Jinjin Shi(Henan Key Laboratory of Targeting Therapy and Diagnosis for Critical Diseases,School of Pharmaceutical Sciences,Zhengzhou University).Boosting 5-ALA-based photodynamic therapy by a liposomal nanomedicine through intracellular iron ion regulation[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Naveed Ullah Khan1,Jiang Ni1,2,Xiufeng Ju1,Tongtong Miao1,Haiyan Chen1,Liang Han1(Jiangsu Key Laboratory of Neuropsychiatric Diseases Research and College of Pharmaceutical Sciences,Soochow University;Department of Pharmacy,Affiliated Hospital of Jiangnan University).Escape from abluminal LRP1-mediated clearance for boosted nanoparticle brain delivery and brain metastasis treatment[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Xu Hu1,Yan Xiao3,Jianan Sun1,Bao Ji1,Shanshan Luo4,Bo Wu5,Chao Zheng6,Peng Wang7,Fanxing Xu8,Keguang Cheng9,Huiming Hua1,Dahong Li1(Key Laboratory of Structure-Based Drug Design & Discovery,Ministry of Education;School of Traditional Chinese Materia Medica,Shenyang Pharmaceutical University;School of Pharmaceutical Engineering,Shenyang Pharmaceutical University;Key Laboratory of Cardiovascular and Cerebrovascular Medicine,Nanjing Medical University;Molecular Imaging Laboratory,MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging,Department of Radiology,Massachusetts General Hospital/Harvard Medical School;PET Center,Department of Radiology and Biomedical Imaging,Yale University School of Medicine;Department of Biomedical Engineering,School of Engineering,China Pharmaceutical University;Wuya College of Innovation,Shenyang Pharmaceutical University;State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources;School of Chemistry and Pharmacy,Guangxi Normal University).New possible silver lining for pancreatic cancer therapy:Hydrogen sulfide and its donors[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Qin Wang1,Xianyan Qin1,Jiyu Fang2,Xun Sun3(Key Laboratory of Advanced Technologies of Materials,Ministry of Education and School of Materials Science and Engineering,Southwest Jiaotong University;Advanced Materials Processing and Analysis Center and Department of Materials Science and Engineering,University of Central Florida;Key Laboratory of Drug Targeting and Drug Delivery Systems,Ministry of Education,West China School of Pharmacy,Sichuan University).Nanomedicines for the treatment of rheumatoid arthritis:State of art and potential therapeutic strategies[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Yuyu Zhu1,Ning Wan2,Xinni Shan1,Guoliang Deng1,Qiang Xu1,Hui Ye2,Yang Sun1,3(State Key Laboratory of Pharmaceutical Biotechnology,Department of Biotechnology and Pharmaceutical Sciences,School of Life Sciences,Nanjing University;Jiangsu Provincial Key Laboratory of Drug Metabolism and Pharmacokinetics,State Key Laboratory of Natural Medicines,China Pharmaceutical University;Chemistry and Biomedicine Innovation Center (Chem BIC),Nanjing University).Celastrol targets adenylyl cyclase-associated protein 1 to reduce macrophages-mediated inflammation and ameliorates high fat diet-induced metabolic syndrome in mice[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Shouyue Zhang1,2,Jin Zhang1,2,3,Yang An4,5,Xiaoxi Zeng6,Ziyi Qin1,2,Yuqian Zhao1,2,Heng Xu2,Bo Liu1(State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University;Department of Laboratory Medicine,State Key Laboratory of Biotherapy,West China Hospital,Sichuan University;School of Pharmaceutical Sciences,Health Science Center,Shenzhen University;Department of Plastic Surgery,Peking University Third Hospital;Division of Plastic Surgery,Brigham and Women’s Hospital,Harvard Medical School;West China Biomedical Big Data Center,West China Hospital,Sichuan University).Multi-omics approaches identify SF3B3 and SIRT3 as candidate autophagic regulators and druggable targets in invasive breast carcinoma[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Zhaoming Lu1,2,Yandan Ren1,Li Yang1,Ang Jia1,Yi Hu1,Yu Zhao1,Wuduo Zhao3,Bin Yu1,Wen Zhao1,Jianying Zhang4,Guiqin Hou1,5(State Key Laboratory of Esophageal Cancer Prevention & Treatment,School of Pharmaceutical Sciences,Zhengzhou University;Collaborative Innovation Center of Cancer Chemoprevention;Center of Advanced Analysis & Gene Sequencing,Zhengzhou University;Henan Academy of Medical and Pharmaceutical Sciences,Zhengzhou University;Key Laboratory of Advanced Drug Preparation Technologies,Ministry of Education,Zhengzhou University).Inhibiting autophagy enhances sulforaphane-induced apoptosis via targeting NRF2 in esophageal squamous cell carcinoma[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Zhiyao Xu1,2,Zhuha Zhou3,Jing Zhang1,Feichao Xuan4,Mengjing Fan1,2,Difan Zhou4,Zhenyu Liuyang4,Ximei Ma4,Yiyang Hong1,Yihong Wang2,Sherven Sharma5,Qinghua Dong1,6,Guanyu Wang4(Biomedical Research Center,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University;Department of Pathology,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University;Department of Gastrointestinal Surgery,the First Affiliated Hospital of Wenzhou Medical University;Department of General Surgery,Sir Run Run Shaw Hospital,School of Medicine,Zhejiang University;David Geffen School of Medicine at UCLA and the Veterans Affairs;Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education).Targeting BMI-1-mediated epitheliale-mesenchymal transition to inhibit colorectal cancer liver metastasis[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Nur Farah Meor Azlan,Maarten P.Koeners,Jinwei Zhang(Institute of Biomedical and Clinical Sciences,Medical School,College of Medicine and Health,University of Exeter,Hatherly Laboratories).Regulatory control of the Na-Cl co-transporter NCC and its therapeutic potential for hypertension[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Liang Jiang1,Yuting Wang1,Qian Lia1,Zhengchao Tu1,Sihua Zhu1,Sanfang Tu2,Zhang Zhang1,Ke Ding1,Xiaoyun Lu1(International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development,Ministry of Education (MOE) of China,School of Pharmacy,Jinan University;Department of Hematology,Zhujiang Hospital,Southern Medical University).Design, synthesis, and biological evaluation of Bcr-Abl PROTACs to overcome T315I mutation[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Zhenzhen Li1,Zhen Guo1,2,Rui Lan1,Sidong Cai1,Zhirong Lin1,Jingyan Li3,Junjian Wang1,Zhuoming Li1,Peiqing Liu1(Department of Pharmacology and Toxicology,School of Pharmaceutical Sciences,National and Local United Engineering Lab of Druggability and New Drugs Evaluation,Guangdong Engineering Laboratory of Druggability and New Drug Evaluation,Guangdong Provincial Key Laboratory of New Drug Design and Evaluation,Sun Yatsen University;Center for Cardiovascular Research and Division of Cardiology,Washington University School of Medicine;International Institute for Translational Chinese Medicine,School of Pharmaceutical Sciences,Guangzhou University of Chinese Medicine).The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy[J].Acta Pharmaceutica Sinica B,2021,第5期
  • Guoshun Luo1,Zhenbang Li1,Xin Lin1,Xinyu Li2,Yu Chen3,Kun Xi2,Maoxu Xiao1,Hanlin Wei1,Lizhe Zhu2,Hua Xiang1(State Key Laboratory of Natural Medicines and Department of Medicinal Chemistry,China Pharmaceutical University;School of Life and Health Sciences and Warshel Institute for Computational Biology,the Chinese University of Hong Kong;Key Laboratory of Smart Drug Delivery,Ministry of Education School of Pharmacy,Fudan University).Discovery of an orally active VHL-recruiting PROTAC that achieves robust HMGCR degradation and potent hypolipidemic activity in vivo[J].Acta Pharmaceutica Sinica B,2021,第5期
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