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Hui Liu1,Weimin Qiu1,Tianyu Sun1,Lei Wang1,Chenxi Du1,Yanyu Hu2,Wenyuan Liu1,3,Feng Feng4,2,Yao Chen5,Haopeng Sun1,4(School of Pharmacy,China Pharmaceutical University;Department of Natural Medicinal Chemistry,China Pharmaceutical University;Department of Pharmaceutical Analysis,Key Laboratory of Drug Quality Control and Pharmacovigilance,China Pharmaceutical University;Jiangsu Drug Development Engineering Research Center for Central Degenerative Disease,Jiangsu Food and Pharmaceuticals Science College;School of Pharmacy,Nanjing University of Chinese Medicine).Therapeutic strategies of glioblastoma(GBM):The current advances in the molecular targets and bioactive small molecule compounds[J].Acta Pharmaceutica Sinica B,2022,第4期
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Yang He1,2,3,4,Yuefei Fang1,5,Meng Zhang1,6,Yuge Zhao1,Bin Tu1,2,Mingjie Shi1,Bahtiyor Muhitdinov1,7,Akmal Asrorov1,7,Qin Xu5,Yongzhuo Huang1,2,3,8(State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Zhongshan Institute for Drug Discovery,Chinese Academy of Sciences;Department of Pharmacy,the First Affiliated Hospital of Zhengzhou University;Artemisinin Research Center,Guangzhou University of Chinese Medicine;Women's Hospital,School of Medicine,Zhejiang University;Institute of Bioorganic Chemistry,Uzbekistan Academy of Sciences;National Medical Products Administration,Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients).Remodeling “cold” tumor immune microenvironment via epigenetic-based therapy using targeted liposomes with in situ formed albumin corona[J].Acta Pharmaceutica Sinica B,2022,第4期
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Shuai Guo,Kening Li,Yanwen Chen,Bin Li(State Key Laboratory of Natural Medicines and School of Traditional Chinese Pharmacy,China Pharmaceutical University).Unraveling the drug distribution in brain enabled by MALDI MS imaging with laser-assisted chemical transfer[J].Acta Pharmaceutica Sinica B,2022,第4期
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Yongrong Yao,Huachao Chen,Ninghua Tan(State Key Laboratory of Natural Medicines,School of Traditional Chinese Pharmacy,China Pharmaceutical University).Cancer-cell-biomimetic nanoparticles systemically eliminate hypoxia tumors by synergistic chemotherapy and checkpoint blockade immunotherapy[J].Acta Pharmaceutica Sinica B,2022,第4期
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Zhiqiang Deng1,Yu Dong1,Xiaoting Zhou2,3,Jia-Hong Lu1,Zhenyu Yue2(State Key Laboratory of Quality Research in Chinese Medicine,Institute of Chinese Medical Sciences,University of Macau;Department of Neurology,the Friedman Brain Institute,Icahn School of Medicine at Mount Sinai;Department of Geriatrics,Xiangya Hospital,Central South University).Pharmacological modulation of autophagy for Alzheimer’s disease therapy:Opportunities and obstacles[J].Acta Pharmaceutica Sinica B,2022,第4期
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Jie Zhou1,Wei Xu1,Zezhong Liu1,Chao Wang2,Shuai Xia1,Qiaoshuai Lan1,Yanxing Cai1,Shan Su1,Jing Pu1,Lixiao Xing1,Youhua Xie1,Lu Lu1,Shibo Jiang1,Qian Wang1(Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS),School of Basic Medical Sciences and BSL-3 Facility,Shanghai Institute of Infectious Diseases and Biosecurity,Fudan University;State Key Laboratory of Toxicology and Medical Countermeasures,Beijing Institute of Pharmacology and Toxicology).A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases[J].Acta Pharmaceutica Sinica B,2022,第4期
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Xuejing Shao1,Yingqian Chen1,Wei Wang1,Wenxin Du1,Xingya Zhang1,Minyi Cai1,Shaowei Bing1,Ji Cao1,2,3,Xiaojun Xu4,Bo Yang1,3,Qiaojun He1,2,3,Meidan Ying1,4,2(Institute of Pharmacology and Toxicology,Zhejiang Province Key Laboratory of Anti-Cancer Drug Research,College of Pharmaceutical Sciences,Zhejiang University;Cancer Center,Zhejiang University;Innovation Institute for Artificial Intelligence in Medicine,Zhejiang University;Children's Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health).Blockade of deubiquitinase YOD1 degrades oncogenic PML/RARα and eradicates acute promyelocytic leukemia cells[J].Acta Pharmaceutica Sinica B,2022,第4期
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Zhidi Pan1,Jie Chen1,Xiaodong Xiao2,3,Yueqing Xie2,Hua Jiang2,3,Baohong Zhang1,Huili Lu1,Yunsheng Yuan1,Lei Han3,Yuexian Zhou1,Huifang Zong1,Lei Wang1,Rui Sun1,Jianwei Zhu1,2,3(Engineering Research Center of Cell&Therapeutic Antibody,MOE,School of Pharmacy,Shanghai Jiao Tong University;Jecho Laboratories,Inc.;Jecho Biopharmaceuticals Co.,Ltd.).Characterization of a novel bispecific antibody targeting tissue factor-positive tumors with T cell engagement[J].Acta Pharmaceutica Sinica B,2022,第4期
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Minsong Guo1,Fengdan Zhu1,Wenqiao Qiu1,2,Gan Qiao1,Betty Yuen-Kwan Law3,Lu Yu1,Jianming Wu1,Yong Tang1,3,Chonglin Yu1,Dalian Qin1,Xiaogang Zhou1,Anguo Wu1(Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation,Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica,School of Pharmacy,Education Ministry Key Laboratory of Medical Electrophysiology,Southwest Medical University;Department of Neurosurgery Sichuan Provincial People's Hospital,University of Electronic Science and Technology of China;State Key Laboratory of Quality Research in Chinese Medicine,Macau University of Science and Technology).High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC-DAD-Q/TOF-MS/MS[J].Acta Pharmaceutica Sinica B,2022,第4期
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Sameera Senaweera1,Tiffany C.Edwards1,Jayakanth Kankanala1,Yan Wang1,2,Rajkumar Lalji Sahani1,Jiashu Xie1,Robert J.Geraghty1,Zhengqiang Wang1(Center for Drug Design,College of Pharmacy,University of Minnesota;Translational Medicine R&D Center,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences).Discovery of N-benzyl hydroxypyridone carboxamides as a novel and potent antiviral chemotype against human cytomegalovirus(HCMV)[J].Acta Pharmaceutica Sinica B,2022,第4期
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Chuanbin Yang1,2,Chengfu Su1,3,4,Ashok Iyaswamy1,3,Senthil Kumar Krishnamoorthi1,Zhou Zhu1,3,Sichang Yang1,Benjamin Chunkit Tong1,3,Jia Liu1,3,Sravan G.Sreenivasmurthy1,3,Xinjie Guan1,Yuxuan Kan1,Aston Jiaxi Wu1,Alexis Shiying Huang1,Jieqiong Tan5,Kingho Cheung1,3,Juxian Song1,6,Min Li1,3(Mr.&Mrs.Ko Chi-Ming Centre for Parkinson's Disease Research,School of Chinese Medicine,Hong Kong Baptist University;Department of Geriatrics,Shenzhen People's Hospital(the Second Clinical Medical College,Jinan University,the First Affiliated Hospital,Southern University of Science and Technology);Institute for Research and Continuing Education,Hong Kong Baptist University;College of Pharmacy,Henan University of Chinese Medicine;Center for Medical Genetics and Hunan Key Laboratory of Animal Model for Human Diseases,School of Life Sciences,Central South University;Medical College of Acupuncture-Moxibustion and Rehabilitation,Guangzhou University of Chinese Medicine).Celastrol enhances transcription factor EB(TFEB)-mediated autophagy and mitigates Tau pathology:Implications for Alzheimer’s disease therapy[J].Acta Pharmaceutica Sinica B,2022,第4期
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Jun Wang,Yanmei Hu,Madeleine Zheng(Department of Pharmacology and Toxicology,College of Pharmacy,the University of Arizona).Enterovirus A71 antivirals:Past, present, and future[J].Acta Pharmaceutica Sinica B,2022,第4期
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Mengqi Xu1,Cong Mao2,Haoting Chen2,Lu Liu3,Yabin Wang1,Abid Hussain3,Sulei Li1,Xu Zhang4,Ruslan G.Tuguntaev2,Xing-Jie Liang3,Weisheng Guo2,Feng Cao1(Department of Cardiology,National Clinical Research Center for Geriatric Diseases&Second Medical Center of Chinese PLA General Hospital;Department of Minimally Invasive Interventional Radiology,Key Laboratory of Molecular Target&Clinical Pharmacology,School of Pharmaceutical Sciences&the Second Affiliated Hospital,Guangzhou Medical University;Laboratory of Controllable Nanopharmaceuticals,Chinese Academy of Sciences(CAS)Center for Excellence in Nanoscience and CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety,National Center for Nanoscience and Technology;Department of Urology,Chinese PLA General Hospital).Osteopontin targeted theranostic nanoprobes for laser-induced synergistic regression of vulnerable atherosclerotic plaques[J].Acta Pharmaceutica Sinica B,2022,第4期
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Saba R.Aliyari1,Amir Ali Ghaffari1,Olivier Pernet1,2,Kislay Parvatiyar1,Yao Wang1,Hoda Gerami1,Ann-Jay Tong1,Laurent Vergnes3,Armin Takallou1,Adel Zhang1,Xiaochao Wei4,Linda D.Chilin5,Yuntao Wu5,Clay F.Semenkovich4,6,Karen Reue3,Stephen T.Smale1,Benhur Lee1,Genhong Cheng1(Department of Microbiology,Immunology and Molecular Genetics,University of California;En Viro International Laboratories;Department of Human Genetics,David Geffen School of Medicine,University of California;Division of Endocrinology,Metabolism and Lipid Research,Washington University School of Medicine;Center for Infectious Disease Research,School of Systems Biology,George Mason University Manassas;Diabetic Cardiovascular Disease Center,Washington,University School of Medicine).Suppressing fatty acid synthase by type Ⅰ interferon and chemical inhibitors as a broad spectrum anti-viral strategy against SARS-CoV-2[J].Acta Pharmaceutica Sinica B,2022,第4期
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Boyi Niu1,Yixian Zhou1,Kaixin Liao1,Ting Wen1,Sixian Lao1,Guilan Quan2,Xin Pan1,Chuanbin Wu1,2(School of Pharmaceutical Sciences,Sun Yat-sen University;College of Pharmacy,Jinan University).“Pincer movement”:Reversing cisplatin resistance based on simultaneous glutathione depletion and glutathione S-transferases inhibition by redox-responsive degradable organosilica hybrid nanoparticles[J].Acta Pharmaceutica Sinica B,2022,第4期
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Chunlong Ma,Haozhou Tan,Juliana Choza,Yuyin Wang,Jun Wang(Department of Pharmacology and Toxicology,College of Pharmacy,the University of Arizona).Validation and invalidation of SARS-CoV-2 main protease inhibitors using the Flip-GFP and Protease-Glo luciferase assays[J].Acta Pharmaceutica Sinica B,2022,第4期
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Zhiwei Zhang1,2,Suling Ding1,Zhe Wang3,Xiaowei Zhu1,Zheliang Zhou1,Weiwei Zhang1,Xiangdong Yang1,3,4,5,Junbo Ge1,3,4,5(Institutes of Biomedical Sciences and Shanghai Institute of Cardiovascular Diseases,Zhongshan Hospital,Fudan University;Reproductive Medicine Centre,Zhongshan Hospital,Fudan University;Department of Cardiology,Zhongshan Hospital,Fudan University;NHC Key Laboratory of Viral Heart Diseases,Fudan University;Key Laboratory of Viral Heart Diseases,Chinese Academy of Medical Sciences).Prmt1 upregulated by Hdc deficiency aggravates acute myocardial infarction via NETosis[J].Acta Pharmaceutica Sinica B,2022,第4期
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Hsiang-i Tsai1,2,Yanping Wu1,Rui Huang3,Dandan Su1,Yingyi Wu1,Xiaoyan Liu1,Linglu Wang1,Zhanxue Xu1,Yuxin Pang4,Chong Sun5,Chao He1,Fan Shu1,Haitao Zhu2,Dongqing Wang2,Fang Cheng1,Laiqiang Huang6,Hongbo Chen1(School of Pharmaceutical Sciences(Shenzhen),Sun Yat-sen University;Department of Medical Imaging,the Affiliated Hospital of Jiangsu University;Department of Hematology,Zhujiang Hospital,Southern Medical University;School of Traditional Medicine Materials Resource,Guangdong Pharmaceutical University;Immune Regulation in Cancer,German Cancer Research Center;The Shenzhen Key Lab of Gene and Antibody Therapy,Center for Biotechnology&Biomedicine,Division of Life and Health Sciences,Graduate School at Shenzhen,Tsinghua University).PHF6 functions as a tumor suppressor by recruiting methyltransferase SUV39H1 to nucleolar region and offers a novel therapeutic target for PHF6-muntant leukemia[J].Acta Pharmaceutica Sinica B,2022,第4期
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Yunlong Shan1,Qi Ni1,Qixiang Zhang1,Mengying Zhang1,Bin Wei2,Lingge Cheng1,Chongjin Zhong1,Xinyu Wang1,Qingqing Wang1,Jiali Liu1,Jingwei Zhang1,Jingjing Wu2,Guangji Wang1,Fang Zhou1(Key Laboratory of Drug Metabolism and Pharmacokinetics,State Key Laboratory of Natural Medicines,China Pharmaceutical University;Department of Hematology and Oncology,the Affiliated Huaian No.1 People's Hospital of Nanjing Medical University).Targeting tumor endothelial hyperglycolysis enhances immunotherapy through remodeling tumor microenvironment[J].Acta Pharmaceutica Sinica B,2022,第4期
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Yuyun Tang1,Jinchao Gao1,Tao Wang2,Qian Zhang1,Antian Wang1,Meng Huang1,Renhe Yu1,Hongzhuan Chen1,3,Xiaoling Gao1(Department of Pharmacology and Chemical Biology,Shanghai Universities Collaborative Innovation Center for Translational Medicine,Shanghai Jiao Tong University School of Medicine;Department of Geriatric Psychiatry,Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Alzheimer's Disease and Related Disorder Center,Shanghai Jiao Tong University;Institute of Interdisciplinary Integrative Biomedical Research,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine).The effect of drug loading and multiple administration on the protein corona formation and brain delivery property of PEG-PLA nanoparticles[J].Acta Pharmaceutica Sinica B,2022,第4期
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Zhong Li1,2,Jimin Xu3,Yuekun Lang2,Xiangmeng Wu1,Saiyang Hu2,Subodh Kumar Samrat1,2,Anil M.Tharappel1,2,Lili Kuo2,David Butler4,Yongcheng Song5,Qing-Yu Zhang1,Jia Zhou3,Hongmin Li1,2(Department of Pharmacology and Toxicology,College of Pharmacy;Wadsworth Center,New York State Department of Health;Chemical Biology Program,Department of Pharmacology and Toxicology,University of Texas Medical Branch;The Neural Stem Cell Institute;Department of Pharmacology and Chemical Biology,Baylor College of Medicine).In vitro and in vivo characterization of erythrosin B and derivatives against Zika virus[J].Acta Pharmaceutica Sinica B,2022,第4期
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Songli Wang1,2,Ruifeng Wang1,Nana Meng1,Linwei Lu3,Jun Wang1,Jianfen Zhou1,Jiasheng Lu1,Qianzhu Xu1,Cao Xie1,Changyou Zhan1,2,Yao Li4,Yang Yu4,Weiyue Lu1,5,6,Min Liu1(Department of Pharmaceutics,School of Pharmacy,Key Laboratory of Smart Drug Delivery(Ministry of Education and PLA),Fudan University;Department of Pharmacology,School of Basic Medical Sciences,Fudan University;The Department of Integrative Medicine,Huashan Hospital,Fudan University and the Institutes of Integrative Medicine of Fudan University;The National Facility for Protein Science in Shanghai(NFPS);State Key Laboratory of Medical Neurobiology and the Collaborative Innovation Center for Brain Science and Department of Pharmacology,School of Basic Medical Sciences,Fudan University;Minhang Branch,Zhongshan Hospital and Institute of Fudan-Minhang Academic Health System,Minhang Hospital,Fudan University).Engineered platelets-based drug delivery platform for targeted thrombolysis[J].Acta Pharmaceutica Sinica B,2022,第4期
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Hong Wang1,Qianqian Wang1,Guodi Cai1,Zhijian Duan2,Zoann Nugent3,Jie Huang4,Jianwei Zheng1,Alexander D.Borowsky5,Jian Jian Li6,Peiqing Liu1,7,Hsing-Jien Kung2,8,Leigh Murphy3,Hong-Wu Chen2,8,Junjian Wang1,7(School of Pharmaceutical Sciences,Sun Yat-sen University;Department of Biochemistry and Molecular Medicine,University of California;Research Institute in Oncology and Hematology,University of Manitoba and Cancer Care Manitoba;Guangdong Lung Cancer Institute,Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer,Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences;Department of Pathology and Laboratory Medicine,University of California;Department of Radiation Oncology,University of California;National-Local Joint Engineering Laboratory of Druggability and New Drugs Evaluation,Guangdong Provincial Key Laboratory of New Drug Design and Evaluation,Sun Yat-sen University;UC Davis Comprehensive Cancer Center,School of Medicine,University of California).Nuclear TIGAR mediates an epigenetic and metabolic autoregulatory loop via NRF2 in cancer therapeutic resistance[J].Acta Pharmaceutica Sinica B,2022,第4期
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Qi Wang1,2,Bixi Tang3,2,4,Dandan Sun5,Ying Dong3,2,Yinchun Ji6,Huanyu Shi1,2,Liwei Zhou1,7,Yueyue Yang1,2,Menglan Luo1,8,Qian Tan3,Lin Chen1,Yue Dong9,Cong Li3,Rongrong Xie3,Yi Zang3,2,10,Jingkang Shen1,Bing Xiong1,2,Jia Li3,2,5,10,Danqi Chen1(Department of Medicinal Chemistry,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;University of Chinese Academy of Sciences;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;Department of Pharmacology,School of Pharmacy,Fudan University;School of Chinese Materia Medica,Nanjing University of Chinese Medicine;Division of Anti-tumor Pharmacology,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;Center for Supramolecular Chemistry and Catalysis and Department of Chemistry,College of Sciences,Shanghai University;Department of Chemistry,College of Sciences,Shanghai University;Department of Pulmonary and Critical Care Medicine,Shanghai Fifth People’s Hospital,Fudan University;School of Pharmaceutical Science and Technology,Hangzhou Institute for Advanced Study,UCAS).Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifiuoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis[J].Acta Pharmaceutica Sinica B,2022,第4期
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Mélanie Robert1,2,3,Bastien Laperrousaz1,Diana Piedrahita1,Emilie-Fleur Gautier3,4,Travis Nemkov5,6,Florian Dupuy4,7,Elie Nader2,3,Virginie Salnot4,Patrick Mayeux3,4,Angelo D’Alessandro5,6,Catherine Lavazec4,7,Philippe Joly2,3,8,Alexander Scheer1,Philippe Connes2,3,Agnès Cibiel1(Erytech Pharma;Laboratoire interuniversitaire de Biologie de la Motricité(LIBM)EA7424,Team?Vascular Biology and Red Blood Cell?,Université Claude Bernard Lyon 1,Université de Lyon;Labex GR-Ex;3P5 proteom’IC facility,Université de Paris,Institut Cochin,INSERM,CNRS;University of Colorado,Anschutz Medical Campus;Omix Technologies,Inc.;Inserm U1016,CNRS 8104,Université de Paris,Institut Cochin;Laboratoire de Biochimie et de Biologie Moléculaire,UF de biochimie des pathologies érythrocytaires,Centre de Biologie et de Pathologie Est,Hospices Civils de Lyon).Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process[J].Acta Pharmaceutica Sinica B,2022,第4期
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Rong Xiang1,Zhengsen Yu1,Yang Wang1,Lili Wang2,Shanshan Huo1,Yanbai Li1,Ruiying Liang1,Qinghong Hao1,Tianlei Ying3,Yaning Gao4,Fei Yu1,Shibo Jiang3(College of Life Sciences,Hebei Agricultural University;Research Center of Chinese Jujube,Hebei Agricultural University;Key Laboratory of Medical Molecular Virology(MOE/NHC/CAMS),School of Basic Medical Sciences,Shanghai Institute of Infectious Diseases and Biosecurity,Fudan University;Beijing Pharma and Biotech Center).Recent advances in developing small-molecule inhibitors against SARS-CoV-2[J].Acta Pharmaceutica Sinica B,2022,第4期
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Lei Feng1,2,Xiangge Tian2,Dahong Yao3,Zhenlong Yu2,Xiaokui Huo1,2,Zhenhao Tian4,Jing Ning2,Jingnan Cui4,Tony D.James5,6,Xiaochi Ma1,2(Second Affiliated Hospital,Dalian Medical University;College of Pharmacy,the National&Local Joint Engineering Research Center for Drug Development of Neurodegenerative Disease,Dalian Medical University;School of Pharmaceutical Sciences,Shenzhen Technology University;State Key Laboratory of Fine Chemicals,Dalian University of Technology;Department of Chemistry,University of Bath;School of Chemistry and Chemical Engineering,Henan Normal University).A practical strategy to develop isoform-selective near-infrared fiuorescent probes for human cytochrome P450 enzymes[J].Acta Pharmaceutica Sinica B,2022,第4期
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He Xueqin,Wang Xiaorong,Yang Lianyi,Yang Zhihang,Yu Wenqi,Wang Yazhen,Liu Rui,Chen Meiwan,Gao Huile(West China School of Pharmacy,Sichuan University,Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province,Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology;Institute of Chinese Medical Sciences,University of Macau,State Key Laboratory of Quality Research in Chinese Medicine).Intelligent lesion blood-brain barrier targeting nano-missiles for Alzheimers disease treatment by anti-neuroinflammation and neuroprotection[J].Acta Pharmaceutica Sinica B,2022,第4期
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Guo Minsong Zhu Fengdan Qiu Wenqiao Qiao Gan Law Betty Yuenkwan Yu Lu Wu Jianming Tang Yong Yu Chonglin Qin Dalian Zhou Xiaogang Wu Anguo(School of Pharmacy, Southwest Medical University, Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation;Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica;Education Ministry Key Laboratory of Medical Electrophysiology, Luzhou, 646000;Department of Neurosurgery Sichuan Provincial Peoples Hospital, University of Electronic Science and Technology of China, Chengdu, 610000;Macau University of Science and Technology, State Key Laboratory of Quality Research in Chinese Medicine, Macau, Taipa, 999078;Macau University of Science and Technology, State Key, Macau, Taipa, 999078).High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLCLDAD-Q/TOF-MS/MS[J].Acta Pharmaceutica Sinica B,2022,第4期
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Zhiwei Xiao1,2,Huiyi Wei1,Yi Xu3,Ahmed Haider2,Junjie Wei1,Shiyu Yuan1,Jian Rong2,Chunyu Zhao2,Guocong Li1,Weibin Zhang4,Huangcan Chen4,Yuefeng Li5,Lingling Zhang1,Jiyun Sun1,2,Shaojuan Zhang1,Hai-Bin Luo6,Sen Yan7,Qijun Cai1,Lu Hou1,Chao Che4,Steven H.Liang2,Lu Wang1(Center of Cyclotron and PET Radiopharmaceuticals,Department of Nuclear Medicine and PET/CT-MRI Center,the First Affiliated Hospital of Jinan University;Division of Nuclear Medicine and Molecular Imaging,Massachusetts General Hospital&Department of Radiology,Harvard Medical School;Department of Cardiology,the First Affiliated Hospital of Jinan University;State Key Laboratory of Chemical Oncogenomics,Key Laboratory of Chemical Genomics,Peking University Shenzhen Graduate School;Guangdong Landau Biotechnology Co.Ltd.;Key Laboratory of Tropical Biological Resources of Ministry of Education,School of Pharmaceutical Sciences,Hainan University;Guangdong-Hongkong-Macau Institute of CNS Regeneration,Ministry of Education CNS Regeneration Collaborative Joint Laboratory,Jinan University).Discovery of a highly specific 18F-labeled PET ligand for phosphodiesterase 10A enabled by novel spirocyclic iodonium ylide radiofiuorination[J].Acta Pharmaceutica Sinica B,2022,第4期
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