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Yu-meng Miao,Ya-jing Zhang,Si-miao Qiao,Yu-feng Xia,Zhi-feng Wei,Yue Dai(Department of Pharmacology of Chinese Materia Medica,School of Traditional Chinese Pharmacy,China Pharmaceutical University,Nanjing 210009,China).Oral administration of curcumin ameliorates pulmonary fibrosis in mice through 15d-PGJ2-mediated induction of hepatocyte growth factor in the colon[J].中国药理学报(英文版),2021,第3期
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Fang-fang Li,Yu-lai Liang,Xiao-shuai Han,Ya-na Guan,Jian Chen,Ping Wu,Xian-xian Zhao,Qing Jing(Department of Cardiology,Shanghai General Hospital,School of Medicine,Shanghai JiaoTong University,Hongkou District,Shanghai 200080,China;Key Laboratory of Stem Cell Biology,Shanghai Jiao Tong University School of Medicine(SJTUSM)&Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS),Shanghai 200031,China;CAS Key Laboratory of Tissue Microenvironment and Tumor,Shanghai Institutes for Biological Sciences,University of Chinese Academy of Sciences,Chinese Academy of Sciences(CAS),Shanghai 200031,China;Key Laboratory of Stem Cell Biology,Shanghai Jiao Tong University School of Medicine(SJTUSM)&Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS),Shanghai 200031,China;National Facility for Protein Science,Shanghai 201210,China;Department of Cardiology,Changhai Hospital,Shanghai 200433,China;Key Laboratory of Stem Cell Biology,Shanghai Jiao Tong University School of Medicine(SJTUSM)&Shanghai Institutes for Biological Sciences(SIBS),Chinese Academy of Sciences(CAS),Shanghai 200031,China;CAS Key Laboratory of Tissue Microenvironment and Tumor,Shanghai Institutes for Biological Sciences,University of Chinese Academy of Sciences,Chinese Academy of Sciences(CAS),Shanghai 200031,China).ADP receptor P2y12 prevents excessive primitive hematopoiesis in zebrafish by inhibiting Gata1[J].中国药理学报(英文版),2021,第3期
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Shu Song,Yue Ding,Guo-liang Dai,Yue Zhang,Meng-ting Xu,Jie-ru Shen,Ting-ting Chen,Yun Chen,Guo-liang Meng(Department of Pharmacology,School of Pharmacy,Nantong University,Nantong 226001,China;Key Laboratory of Inflammation and Molecular Drug Target of Jiangsu Province,Nantong University,Nantong 226001,China;Department of Clinical Pharmacology,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China).Sirtuin 3 deficiency exacerbates diabetic cardiomyopathy via necroptosis enhancement and NLRP3 activation[J].中国药理学报(英文版),2021,第2期
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Zhong-jie Li,Hui-qi Dai,Xiao-wei Huang,Ji Feng,Jing-huan Deng,Zi-xuan Wang,Xiao-mei Yang,Yu-jia Liu,Yong Wu,Pan-hong Chen,Huan Shi,Ji-gang Wang,Jing Zhou,Guo-dong Lu(Department of Physiology,School of Preclinical Medicine,Guangxi Medical University,Nanning 530021,China;Department of Toxicology,School of Public Health,Guangxi Medical University,Nanning 530021,China;Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases,Guangxi Medical University,Nanning 530021,China;Artemisinin Research Center and Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Shenzhen People's Hospital,Shenzhen 518020,China;Key Laboratory of High-incidence-Tumor Prevention&Treatment(Guangxi Medical University),Ministry of Education of China,Nanning 530021,China;Cancer Science Institute of Singapore,National University of Singapore,14 Medical Drive,Singapore 117599,Singapore).Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma[J].中国药理学报(英文版),2021,第2期
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Pei-pei Zhang,Zhao-fu Guo,Pei-hua Zhang,Zhi-pei Liu,Lv Song,Ze-fu Zhang,Yu-zhong Jia,Zhen-zhen Cao,Ji-hua Ma(Cardiac Electrophysiological Research Laboratory,Medical College,Wuhan University of Science and Technology,Wuhan 430065,China).Eleutheroside B, a selective late sodium current inhibitor, suppresses atrial fibrillation induced by sea anemone toxin II in rabbit hearts[J].中国药理学报(英文版),2021,第2期
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Lu-lu Pan,Yong Yang,Min Hui,Shuo Wang,Cui-yun Li,Hong Zhang,Yan-hua Ding,Li Fu,Xing-xing Diao,Da-fang Zhong(State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;Suzhou Haike Medical Technology Co.,Ltd.,Suzhou 215123,China;Dalian Fusheng Pharmaceutical Co.,Ltd.,Dalian 116000,China;The First Hospital of Jilin University,Changchun 130021,China).Sulfation predominates the pharmacokinetics, metabolism, and excretion of forsythin in humans:major enzymes and transporters identified[J].中国药理学报(英文版),2021,第2期
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Man Wu,Guang Lu,Yuan-zhi Lao,Hong Zhang,Dan Zheng,Zhao-qing Zheng,Juan Yi,Qian Xiang,Li-ming Wang,Hong-sheng Tan,Hua Zhou,Han-ming Shen,Hong-xi Xu(Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;School of Pharmacy,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Department of Physiology,Yong Loo Lin School of Medicine,National University of Singapore,Singapore,Singapore;School of Basic Medical Science,Lanzhou University,Lanzhou 730000,China;Faculty of Health Sciences,University of Macau,Macau,China).Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice[J].中国药理学报(英文版),2021,第2期
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Chen-xi Zhao,Chen-ming Zeng,Ke Wang,Qiao-jun He,Bo Yang,Fan-fan Zhou,Hong Zhu(Zhejiang Province Key Laboratory of Anti-Cancer Drug Research,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China;NHC Key Laboratory of Nuclear Medicine,Jiangsu Key Laboratory of Molecular Nuclear Medicine,Jiangsu Institute of Nuclear Medicine,Wuxi 214063,China;Sydney Pharmacy School,The University of Sydney,Camperdown,NSW 2050,Australia).Ubiquitin–proteasome system-targeted therapy for uveal melanoma:what is the evidence?[J].中国药理学报(英文版),2021,第2期
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Lei Du,Xuan Qian,Yuan Li,Xi-zhi Li,Lin-lin He,Liu Xu,Yi-qi Liu,Cheng-cheng Li,Pu Ma,Fang-lin Shu,Qian Lu,Xiao-xing Yin(Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy,Xuzhou Medical University,Xuzhou 221004,China).Sirt1 inhibits renal tubular cell epithelial–mesenchymal transition through YY1 deacetylation in diabetic nephropathy[J].中国药理学报(英文版),2021,第2期
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Yan-yan Yu,Shi-chao Cui,Tian-nan Zheng,Hai-jian Ma,Zhi-fu Xie,Hao-wen Jiang,Yu-feng Li,Ke-xin Zhu,Cheng-gang Huang,Jia Li,Jing-ya Li(State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China).Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice[J].中国药理学报(英文版),2021,第2期
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Dong-liang Tang,Yi-wen Luan,Chun-yi Zhou,Cheng Xiao(School of Anesthesiology,Xuzhou Medical University,Xuzhou 221004,China;Jiangsu Province Key Laboratory of Anesthesiology,Xuzhou Medical University,Xuzhou 221004,China).D2 receptor activation relieves pain hypersensitivity by inhibiting superficial dorsal horn neurons in parkinsonian mice[J].中国药理学报(英文版),2021,第2期
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Jun-shang Huang,Bin-bin Guo,Gai-hong Wang,Li-min Zeng,You-hong Hu,Ting Wang,He-yao Wang(Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China).DGAT1 inhibitors protect pancreatic β-cells from palmitic acid-induced apoptosis[J].中国药理学报(英文版),2021,第2期
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Xiang-chong Wang,Qing-zhong Jia,Yu-lou Yu,Han-dong Wang,Hui-cai Guo,Xin-di Ma,Chun-tong Liu,Xue-yan Chen,Qing-feng Miao,Bing-cai Guan,Su-wen Su,He-ming Wei,Chuan Wang(Department of Pharmacology,The Key Laboratory of Pharmacology and Toxicology for New Drugs,Hebei Medical University,Shijiazhuang 050017,China;The Key Laboratory of Neural and Vascular Biology,Ministry of Education,Hebei Medical University,Shijiazhuang 050017,China;Department of Pharmacology,Hebei Key Laboratory of Chinese Medicine Research on Cardio-cerebrovascular Disease,Hebei Higher Education Institute Applied Technology Research Center on TCM Formula Preparation,Hebei University of Chinese Medicine,Shijiazhuang 050091,China;Depatment of Toxicology,Hebei Medical University,Shijiazhuang 050017,China;Research Laboratory,KK Women's&Children's Hospital,Singapore 229899,Singapore).Inhibition of the INa/K and the activation of peak INa contribute to the arrhythmogenic effects of aconitine and mesaconitine in guinea pigs[J].中国药理学报(英文版),2021,第2期
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Tian-tian Wei,Le-tian Yang,Fan Guo,Si-bei Tao,Lu Cheng,Rong-shuang Huang,Liang Ma,Ping Fu(Division of Nephrology and National Clinical Research Center for Geriatrics,Kidney Research Institute,West China Hospital,Sichuan University,Chengdu 610041,China).Activation of GPR120 in podocytes ameliorates kidney fibrosis and inflammation in diabetic nephropathy[J].中国药理学报(英文版),2021,第2期
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Xia-qing Xu,Xiao-hui Pan,Ting-ting Wang,Jian Wang,Bo Yang,Qiao-jun He,Ling Ding(Zhejiang Province Key Laboratory of Anti-Cancer Drug Research,Institute of Pharmacology and Toxicology,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China).Intrinsic and acquired resistance to CDK4/6 inhibitors and potential overcoming strategies[J].中国药理学报(英文版),2021,第2期
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Xiao-xuan Yu,Meng-yuan Zhu,Jia-rong Wang,Hui Li,Po Hu,Ying-jie Qing,Xiang-yuan Wang,Hong-zheng Wang,Zhan-yu Wang,Jing-yan Xu,Qing-long Guo,Hui Hui(State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Carcinogenesis and Intervention,Key Laboratory of Drug Quality Control and Pharmacovigilance,Ministry of Education,Jiangsu Key Laboratory of Drug Design and Optimization,China Pharmaceutical University,Nanjing 211198,China;Department of Pharmacology,School of Medicine&Holostic Integrative Medicine,Nanjing University of Chinese Medicine,Nanjing 210023,China;Department of Hematology,The Affiliated Drum Tower Hospital of Nanjing University Medical School,Nanjing 210000,China).LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK–eIF2α–ATF4–CHOP axis[J].中国药理学报(英文版),2021,第2期
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Ying Li,Ya-ping Dong,You-wen Qian,Le-xing Yu,Wen Wen,Xiu-liang Cui,Hong-yang Wang(National Center for Liver Cancer,Second Military Medical University,Shanghai 200438,China;The Graduate School of Fujian Medical University,Fuzhou 350122,China;Department of Pathology,Eastern Hepatobiliary Surgery Hospital/Institute,Second Military Medical University,Shanghai 200433,China;International Cooperation Laboratory on Signal Transduction,Eastern Hepatobiliary Surgery Hospital/Institute,Second Military Medical University,Shanghai 200433,China;Ministry of Education(MOE)Key Laboratory on Signaling Regulation and Targeting Therapy of Liver Cancer,Second Military Medical University,Shanghai 200433,China).Identification of important genes and drug repurposing based on clinical-centered analysis across human cancers[J].中国药理学报(英文版),2021,第2期
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Yu Xiaoxuan,Zhu Mengyuan,Wang Jiarong,Li Hui,Hu Po,Qing Yingjie,Wang Xiangyuan,Wang Hongzheng,Wang Zhanyu,Xu Jingyan,Guo Qinglong,Hui Hui.LW-213 induces cell apoptosis in human cutaneous T-cell lymphomas by activating PERK-eIF2alpha-ATF4-CHOP axis[J].中国药理学报,2021,第2期
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Huang Junshang,Guo Binbin,Wang Gaihong,Zeng Limin,Hu Youhong,Wang Ting,Wang Heyao.DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis[J].中国药理学报,2021,第2期
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Ji Feng,Pei-zhi Lu,Guang-zhi Zhu,Shing Chung Hooi,Yong Wu,Xiao-wei Huang,Hui-qi Dai,Pan-hong Chen,Zhong-jie Li,Wen-jing Su,Chuang-ye Han,Xin-ping Ye,Tao Peng,Jing Zhou,Guo-dong Lu(Department of Toxicology,School of Public Health,Guangxi Medical University,Nanning 530021,China;Department of Hepatobiliary Surgery,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China;Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor,Ministry of Education(Guangxi Medical University),Nanning 530021,China;Guangxi Key Laboratory of Early Prevention and Treatment for Regional High Frequency Tumor,Guangxi Medical University,Nanning 530021,China;Department of Physiology,National University of Singapore,2 Medical Drive,Singapore 117593,Singapore;Department of Physiology,School of Preclinical Medicine,Guangxi Medical University,Nanning 530021,China;Guangxi Colleges and Universities Key Laboratory of Prevention and Control of Highly Prevalent Diseases,Guangxi Medical University,Nanning 530021,China;Cancer Science Institute of Singapore,National University of Singapore,14 Medical Drive,Singapore 117599,Singapore).ACSL4 is a predictive biomarker of sorafenib sensitivity in hepatocellular carcinoma[J].中国药理学报(英文版),2021,第1期
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Qian Wu,Li Jiang,Si-cheng Li,Qiao-jun He,Bo Yang,Ji Cao(Zhejiang Province Key Laboratory of Anti-Cancer Drug Research,College of Pharmaceutical Sciences,Zhejiang University,Hangzhou 310058,China).Small molecule inhibitors targeting the PD-1/PD-L1 signaling pathway[J].中国药理学报(英文版),2021,第1期
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Ya-jun Fu,Bo Xu,Shao-wei Huang,Xia Luo,Xiang-liang Deng,Shuang Luo,Chang Liu,Qing Wang,Jin-yan Chen,Lian Zhou(School of Pharmaceutical Sciences,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;School of Chinese Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China;The Second Affiliated Hospital of Guangdong Pharmaceutical University,Yunfu 527300,China;School of Basic Medical Science,Guangzhou University of Chinese Medicine,Guangzhou 510006,China).Baicalin prevents LPS-induced activation of TLR4/NF-κB p65 pathway and inflammation in mice via inhibiting the expression of CD 14[J].中国药理学报(英文版),2021,第1期
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Cheng Chen,Chuan-dong Cheng,Hong Wu,Zuo-wei Wang,Li Wang,Zong-ru Jiang,Ao-li Wang,Chen Hu,Yong-fei Dong,Wan-xiang Niu,Shuang Qi,Zi-ping Qi,Jing Liu,Wen-chao Wang,Chao-shi Niu,Qing-song Liu(High Magnetic Field Laboratory,Key Laboratory of High Magnetic Field and Ion Beam Physical Biology,Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei 230031,China;University of Science and Technology of China,Hefei 230036,China;Department of Neurosurgery,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230036,China;Anhui Province Key Laboratory of Brain Function and Brain Disease,Hefei 230031,China;Precision Medicine Research Laboratory of Anhui Province,Hefei 230088,China;Precision Targeted Therapy Discovery Center,Institute of Technology Innovation,Hefei Institutes of Physical Science,Chinese Academy of Sciences,Hefei 230088,China;Institutes of Physical Science and Information Technology,Anhui University,Hefei 230601,China).Osimertinib successfully combats EGFR-negative glioblastoma cells by inhibiting the MAPK pathway[J].中国药理学报(英文版),2021,第1期
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Shou-yan Wu,Wen-jie Wang,Jin-hui Dou,Li-kun Gong(Center for Drug Safety Evaluation and Research,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;National Center for Natural Products Research,School of Pharmacy,University of Mississippi,University,Oxford,MS 38677,USA).Research progress on the protective effects of licorice-derived 18β-glycyrrhetinic acid against liver injury[J].中国药理学报(英文版),2021,第1期
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Qian Liang,Wei-ming Gu,Ke Huang,Ming-yu Luo,Jing-hua Zou,Guang-lei Zhuang,Hui-min Lei,Hong-zhuan Chen,Liang Zhu,Lu Zhou,Ying Shen(Department of Pharmacology and Chemical Biology,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;Shanghai Collaborative Innovation Center for Translational Medicine,Shanghai 200025,China;Department of Medicinal Chemistry,School of Pharmacy,Fudan University,Shanghai 201203,China;State Key Laboratory of Oncogenes and Related Genes,Department of Obstetrics and Gynecology,Renji Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200240,China;Institute of Interdisciplinary Integrative Biomedical Research,Shuguang Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China).HKB99,an allosteric inhibitor of phosphoglycerate mutase 1,suppresses invasive pseudopodia formation and upregulates plasminogen activator inhibitor-2 in erlotinib-resistant non-small cell lung cancer cells[J].中国药理学报(英文版),2021,第1期
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Jiang-ping Wei,Wen Wen,Yuan Dai,Li-xia Qin,Yue-qiang Wen,Dayue Darrel Duan,Shi-jun Xu(School of Pharmacy,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China;Institute of Material Medica Integration and Transformation for Brain Disorders,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China;School of Health Preservation and Rehabilitation,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China;School of Basic Medicine,Chengdu University of Traditional Chinese Medicine,Chengdu 611137,China;Center for Phenomics of Traditional Chinese Medicine and the Affiliated Traditional Chinese Medicine Hospital,Southwest Medical University,Luzhou 646000,China).Drinking water temperature affects cognitive function and progression of Alzheimer's disease in a mouse model[J].中国药理学报(英文版),2021,第1期
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Jia-lin Shang,Shao-bo Ning,Ying-yi Chen,Tian-xiang Chen,Jian Zhang(State Key Laboratory of Oncogenes and Related Genes,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;Shanghai Lung Cancer Center,Shanghai Chest Hospital,Shanghai Jiao Tong University,Shanghai 200030,China;Medicinal Bioinformatics Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China;School of Pharmaceutical Sciences,Zhengzhou University,Zhengzhou 450001,China).MDL-800,an allosteric activator of SIRT6,suppresses proliferation and enhances EGFR-TKIs therapy in non-small cell lung cancer[J].中国药理学报(英文版),2021,第1期
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Jin-yi Liu,Wei-qi Fu,Xiang-jin Zheng,Wan Li,Li-wen Ren,Jin-hua Wang,Cui Yang,Guan-hua Du(The State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Beijing 100050,China;Key Laboratory of Drug Target Research and Drug Screen,Institute of Materia Medica,Chinese Academy of Medical Science and Peking Union Medical College,Beijing 100050,China;Ethnic Drug Screening & Pharmacology Center,Key Laboratory of Chemistry in Ethnic Medicinal Resources,State Ethnic Affairs Commission & Ministry of Education,Yunnan Minzu University,Kunming 650500,China).Avasimibe exerts anticancer effects on human glioblastoma cells via inducing cell apoptosis and cell cycle arrest[J].中国药理学报(英文版),2021,第1期
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Hai-Ian Zheng,Hai-yue Zhang,Chun-lian Zhu,Hui-ying Li,Sheng Cui,Jian Jin,Shang-guo Piao,Yu-ji Jiang,Mei-ying Xuan,Ji-zhe Jin,Ying-shun Jin,Jung-pyo Lee,Byung-ha Chung,Bum-soon Choi,Chul-woo Yang,Can Li(Department of Nephrology,Yanbian University Hospital,Yanji 133000,China;College of Chemical and Life Science,Changchun University of Technology,Changchun 130000,China;Transplantation Research Center,Department of Internal Medicine,Seoul St.Mary's Hospital,The Catholic University of Korea,Seoul 06591,Korea;Department of Health Examination Central,Yanbian University,Yanji 133000,China;Division of Nephrology,Department of Internal Medicine,Seoul National University College of Medicine,Seoul 07061,Korea;Division of Nephrology,Department of Internal Medicine,Seoul St.Mary's Hospital,College of Medicine,The Catholic University of Korea,Seoul 06591,Korea).L-carnitine protects against tacrolimus-induced renal injury by attenuating programmed cell death via PI3K/AKT/PTEN signaling[J].中国药理学报(英文版),2021,第1期
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Tai Rao,Ya-ting Liu,Xiang-chang Zeng,Chao-peng Li,Dong-sheng Ou-Yang(Department of Clinical Pharmacology,Xiangya Hospital,Central South University,Changsha 410008,China;Hunan Key Laboratory of Pharmacogenetics,Institute of Clinical Pharmacology,Central South University,Changsha 410008,China;Engineering Research Center of Applied Technology of Pharmacogenomics,Ministry of Education,Changsha 410008,China;National Clinical Research Center for Geriatric Disorders,Changsha 410008,China;Hunan Key Laboratory for Bioanalysis of Complex Matrix Samples,Changsha 410205,China).The hepatotoxicity of Polygonum multiflorum:The emerging role of the immune-mediated liver injury[J].中国药理学报(英文版),2021,第1期
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