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Guo Minsong Zhu Fengdan Qiu Wenqiao Qiao Gan Law Betty Yuenkwan Yu Lu Wu Jianming Tang Yong Yu Chonglin Qin Dalian Zhou Xiaogang Wu Anguo（School of Pharmacy， Southwest Medical University， Sichuan Key Medical Laboratory of New Drug Discovery and Druggability Evaluation；Luzhou Key Laboratory of Activity Screening and Druggability Evaluation for Chinese Materia Medica；Education Ministry Key Laboratory of Medical Electrophysiology， Luzhou， 646000;Department of Neurosurgery Sichuan Provincial Peoples Hospital， University of Electronic Science and Technology of China， Chengdu， 610000;Macau University of Science and Technology， State Key Laboratory of Quality Research in Chinese Medicine， Macau， Taipa， 999078;Macau University of Science and Technology， State Key， Macau， Taipa， 999078）.High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLCLDAD-Q/TOF-MS/MS[J].Acta Pharmaceutica Sinica B,2022,第4期
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Wang Pengcheng，Zeng Guangyi，Yan Yu，Zhang Songyang，Dong Yongqiang，Zhang Yangming，Zhang Xingzhong，Liu Huiying，Zhang Zhipeng，Jiang Changtao，Pang Yanli（Department of Physiology and Pathophysiology， School of Basic Medical Sciences， Peking University， Key Laboratory of Molecular Cardiovascular Science， Ministry of Education， Beijing， 100191;Center of Basic Medical Research， Institute of Medical Innovation and Research， Peking University Third Hospital， Beijing， 100191;Center for Obesity and Metabolic Disease R， Beijing， 100191;Center for Obesity and Metabolic Disease Research， School of Basic Medical Sciences， Peking University， Beijing， 100191;General Surgery Department， Peking University Third Hospital， Beijing， 100191;Center for Reproductive Medicine， Department of Obstetrics and Gynecology， Peking University Third Hospital， Beijing， 100191）.Disruption of adipocyte HIF-1a improves atherosclerosis through the inhibition of ceramide generation[J].Acta Pharmaceutica Sinica B,2022,第4期
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He Xueqin，Wang Xiaorong，Yang Lianyi，Yang Zhihang，Yu Wenqi，Wang Yazhen，Liu Rui，Chen Meiwan，Gao Huile（West China School of Pharmacy，Sichuan University，Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province，Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology；Institute of Chinese Medical Sciences，University of Macau，State Key Laboratory of Quality Research in Chinese Medicine）.Intelligent lesion blood-brain barrier targeting nano-missiles for Alzheimers disease treatment by anti-neuroinflammation and neuroprotection[J].Acta Pharmaceutica Sinica B,2022,第4期
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Hongxi Hu，Xiaotong Lu，Huiyan Xu，Liyun Zhou（Pharmcube（Beijing）Co.，Ltd.）.Analysis of new drug registration and review in China in 2021[J].Acta Pharmaceutica Sinica B,2022,第4期
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Jun Wang1，Hongmin Li2（Department of Medicinal Chemistry，Ernest Mario School of Pharmacy，Rutgers，the State University of New Jersey；Department of Pharmacology and Toxicology，College of Pharmacy，University of Arizona）.Editorial of Special Column on Antiviral Drug Discovery and Pharmacology[J].Acta Pharmaceutica Sinica B,2022,第4期
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Songtao Dong1，Xiangnan Guo1，Fei Han2，Zhonggui He1，Yongjun Wang1（Department of Pharmaceutics，Wuya College of Innovation，Shenyang Pharmaceutical University；School of Pharmacy，Shenyang Pharmaceutical University）.Emerging role of natural products in cancer immunotherapy[J].Acta Pharmaceutica Sinica B,2022,第3期
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Zhiwei Fan1,2，Changyue Wu2,3，Miaomiao Chen2，Yongying Jiang4，Yuanyuan Wu2，Renfang Mao4，Yihui Fan1,2（Department of Pathogenic Biology，School of Medicine，Nantong University；Laboratory of Medical Science，School of Medicine，Nantong University；Department of Dermatology，Affiliated Hospital of Nantong University，Nantong University；Department of Pathophysiology，School of Medicine，Nantong University）.The generation of PD-L1 and PD-L2 in cancer cells：From nuclear chromatin reorganization to extracellular presentation[J].Acta Pharmaceutica Sinica B,2022,第3期
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Cancan Zheng1，Xiaomei Yu1，Yiyao Liang2，Yidong Zhu3，Yan He3，Long Liao1，Dingkang Wang1，Yanming Yang1，Xingfeng Yin1，Ang Li2，Qingyu He1，Bin Li1（MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes，Institute of Life and Health Engineering，Jinan University；Guangdong Key Laboratory of Non-human Primate Research，Guangdong-Hong Kong-Macau Institute of CNS Regeneration，Key Laboratory of CNS Regeneration，Ministry of Education，Jinan University；MOE Key Laboratory of Tumor Molecular Biology and Guangdong Provincial Key Laboratory of Bioengineering Medicine，National Engineering Research Center of Genetic Medicine，Institute of Biomedicine，College of Life Science and Technology，Jinan University）.Targeting PFKL with penfluridol inhibits glycolysis and suppresses esophageal cancer tumorigenesis in an AMPK/FOXO3a/BIM-dependent manner[J].Acta Pharmaceutica Sinica B,2022,第3期
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Geni Ye1,2，Maohua Huang1,2,3，Yong Li1,2，Jie Ouyang1,2，Minfeng Chen1,2，Qing Wen1,2，Xiaobo Li1,2，Huhu Zeng1,2，Pei Long1,2，Zepei Fan4，Junqiang Yin4，Wencai Ye1,2，Dongmei Zhang1,2（College of Pharmacy，Jinan University；Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drugs Research，Jinan University；Integrated Chinese and Western Medicine Postdoctoral Research Station，Jinan University；Department of Musculoskeletal Oncology，the First Affiliated Hospital of Sun Yat-sen University）.The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway[J].Acta Pharmaceutica Sinica B,2022,第3期
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Yingzi He1,2，Zhiwei Zheng1,2，Chang Liu1,2，Wen Li1,2，Liping Zhao1,2，Guohui Nie3，Huawei Li1,2,4,5（ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital，State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science，Fudan University；NHC Key Laboratory of Hearing Medicine (Fudan University)；Department of Otolaryngology and Institute of Translational Medicine，Shenzhen Second People's Hospital/the First Affiliated Hospital of Shenzhen University Health Science Center；Institutes of Biomedical Sciences，Fudan University；The Institutes of Brain Science and the Collaborative Innovation Center for Brain Science，Fudan University）.Inhibiting DNA methylation alleviates cisplatininduced hearing loss by decreasing oxidative stress-induced mitochondria-dependent apoptosis via the LRP1-PI3K/AKT pathway[J].Acta Pharmaceutica Sinica B,2022,第3期
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Fangfang Wang1,2，Sora Jin3，Franklin Mayca Pozo3，Danmei Tian1,2，Xiyang Tang1,2，Yi Dai1,2，Xinsheng Yao1,2，Jinshan Tang1,2，Youwei Zhang3（Institute of Traditional Chinese Medicine and Natural Products，College of Pharmacy，Jinan University；Guangdong Province Key Laboratory of Pharmacodynamic Constituents of Traditional Chinese Medicine and New Drug Research，Jinan University；Department of Pharmacology，Case Comprehensive Cancer Center，Case Western Reserve University School of Medicine）.Chemical screen identifies shikonin as a broad DNA damage response inhibitor that enhances chemotherapy through inhibiting ATM and ATR[J].Acta Pharmaceutica Sinica B,2022,第3期
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Yang Zhou1，Fan Tong1，Weilong Gu1，Siqin He1，Xiaotong Yang1，Jiamei Li1，Yue-Dong Gao2,3，Huile Gao1（Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry，Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology，West China School of Pharmacy，Sichuan University；Core Technology Facility of Kunming Institute of Zoology，Chinese Academy of Sciences；Chinese Academy of Sciences Territorial Core Facility of Kunming Biological Diversity Regional Center）.Co-delivery of photosensitizer and diclofenac through sequentially responsive bilirubin nanocarriers for combating hypoxic tumors[J].Acta Pharmaceutica Sinica B,2022,第3期
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Xu Zhang1,2，Yuxiang Wang1，Linghua Meng1,2（Division of Anti-tumor Pharmacology，Shanghai Institute of Materia Medica，Chinese Academy of Sciences；University of Chinese Academy of Sciences）.Comparative genomic analysis of esophageal squamous cell carcinoma and adenocarcinoma：New opportunities towards molecularly targeted therapy[J].Acta Pharmaceutica Sinica B,2022,第3期
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Pearl Moharil，Zhuoya Wan，Apurva Pardeshi，Jiang Li，Haozhe Huang，Zhangyi Luo，Sanjay Rathod，Ziqian Zhang，Yuang Chen，Bei Zhang，Christian A.Fernandez，Jingjing Sun，Song Li（Center for Pharmacogenetics，Department of Pharmaceutical Science，School of Pharmacy，University of Pittsburgh）.Engineering a folic acid-decorated ultrasmall gemcitabine nanocarrier for breast cancer therapy：Dual targeting of tumor cells and tumor-associated macrophages[J].Acta Pharmaceutica Sinica B,2022,第3期
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Yunhao Wu，Xiu Yu，Yuwei Wang，Yalin Huang，Jiahui Tang，Shuaishuai Gong，Siyu Jiang，Yuanli Xia，Fang Li，Boyang Yu，Yuanyuan Zhang，Junping Kou（State Key Laboratory of Natural Medicines，Jiangsu Key Laboratory of TCM Evaluation and Translational Research，Department of Pharmacology of Chinese Material Medica，School of Traditional Chinese Pharmacy，China Pharmaceutical University）.Ruscogenin alleviates LPS-triggered pulmonary endothelial barrier dysfunction through targeting NMMHC IIA to modulate TLR4signaling[J].Acta Pharmaceutica Sinica B,2022,第3期
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Meiyue Song1，Jiaxin Wang2，Youliang Sun3，Junling Pang1，Xiaona Li1，Yuan Liu4,5,6，Yitian Zhou6,7，Peiran Yang1，Tianhui Fan1，Ying Liu1，Zhaoguo Li8，Xianmei Qi1，Baicun Li1，Xinri Zhang9，Jing Wang1，Chen Wang1,4,5（State Key Laboratory of Medical Molecular Biology，Department of Physiology，Institute of Basic Medical Sciences Chinese Academy of Medical Sciences，School of Basic Medicine Peking Union Medical College；Tsinghua-Peking Center for Life Sciences，Department of Biology，College of Medicine，Tsinghua University；School of Pharmaceutical Sciences，Tsinghua University；Department of Pulmonary and Critical Care Medicine，Center of Respiratory Medicine，China-Japan Friendship Hospital；National Clinical Research Center for Respiratory Diseases；Peking Union Medical College，Chinese Academy of Medical Sciences；Peking Union Medical College，MD Program；Department of Respiratory，the Second Affiliated Hospital of Harbin Medical University；Department of Pulmonary and Critical Care Medicine，the First Hospital of Shanxi Medical University）.Inhibition of gasdermin D-dependent pyroptosis attenuates the progression of silica-induced pulmonary inflammation and fibrosis[J].Acta Pharmaceutica Sinica B,2022,第3期
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Wei Zhang1,,3；Chengchao Xu1,,4；Jichao Sun1；Han-Ming Shen5；Jigang Wang1,,4,6；Chuanbin Yang1（Department of Geriatrics, Shenzhen People’s Hospital (the Second Clinical Medical College, Jinan University；the First Affiliated Hospital, Southern University of Science and Technology)；Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University；Artemisinin Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences；Faculty of Health Sciences, University of Macau；Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University）.Impairment of the autophagy-lysosomal pathway in Alzheimer’s diseases：Pathogenic mechanisms and therapeutic potential[J].Acta Pharmaceutica Sinica B,2022,第3期
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Yumei Wang1，Jia Ke1，Xianmou Guo1，Kaijun Gou1，Zhentao Sang2，Yanbu Wang1,2，Yan Bian2，Sanming Li1，Heran Li2（Department of Pharmaceutics，Shenyang Pharmaceutical University；School of Pharmacy，China Medical University）.Chiral mesoporous silica nano-screws as an efficient biomimetic oral drug delivery platform through multiple topological mechanisms[J].Acta Pharmaceutica Sinica B,2022,第3期
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Guoping Shu1，Yueli Tang1，Mingyuan Yuan1，Ning Wei1，Fangyuan Zhang1，Chunxian Yang1，Xiaozhong Lan2，Min Chen3，Kexuan Tang1，Lien Xiang4，Zhihua Liao1（Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education)，Chongqing Engineering Research Centre for Sweet Potato，SWU-TAAHC Medicinal Plant Joint R&D Centre，School of Life Sciences，Southwest University；TAAHC-SWU Medicinal Plant Joint R&D Centre，Xizang Agricultural and Husbandry College；College of Pharmaceutical Sciences，Southwest University；College of Environmental Science and Engineering，China West Normal University）.Molecular insights into AabZIP1-mediated regulation on artemisinin biosynthesis and drought tolerance in Artemisia annua[J].Acta Pharmaceutica Sinica B,2022,第3期
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Jiwei Cui1,2，Yuanxin Xu1,2，Haiyan Tu1,2，Huacong Zhao1,2，Honglan Wang1,2，Liuqing Di1,2，Ruoning Wang1,2（College of Pharmacy，Nanjing University of Chinese Medicine；Jiangsu Provincial TCM Engineering Technology，Research Center of High Efficient Drug Delivery System）.Gather wisdom to overcome barriers：Well-designed nano-drug delivery systems for treating gliomas[J].Acta Pharmaceutica Sinica B,2022,第3期
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Sha-Sha Cheng1，Yuan-Qing Qu2，Jia Wu1，Guan-Jun Yang1,3,4，Hao Liu5，Wanhe Wang5,6，Qi Huang2，Feng Chen1，Guodong Li1，Chun-Yuen Wong7，Vincent Kam Wai Wong2，Dik-Lung Ma5，Chung-Hang Leung1,8（Institute of Chinese Medical Sciences and State Key Laboratory of Quality Research in Chinese Medicine，University of Macau；Dr.Neher's Biophysics Laboratory for Innovative Drug Discovery，State Key Laboratory of Quality Research in Chinese Medicine，Macau University of Science and Technology；State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products，Ningbo University；Laboratory of Biochemistry and Molecular Biology，School of Marine Sciences，Ningbo University；Department of Chemistry，Hong Kong Baptist University；Institute of Medical Research，Northwestern Polytechnical University；Department of Chemistry，City University of Hong Kong；Department of Biomedical Sciences，Faculty of Health Sciences，University of Macau）.Inhibition of the CDK9-cyclin T1 protein-protein interaction as a new approach against triple-negative breast cancer[J].Acta Pharmaceutica Sinica B,2022,第3期
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Min-Xia Su1，Yu-Lian Xu1，Xiao-Ming Jiang1，Mu-Yang Huang1，Le-Le Zhang1，Luo-Wei Yuan1，Xiao-Huang Xu1，Qi Zhu1，Jian-Li Gao2，Jia-Hong Lu1，Xiuping Chen1，Ming-Qing Huang3，Yitao Wang1，Jin-Jian Lu1,4（State Key Laboratory of Quality Research in Chinese Medicine，Institute of Chinese Medical Sciences，University of Macau；School of Pharmaceutical Sciences，Zhejiang Chinese Medical University；College of Pharmacy，Fujian University of Traditional Chinese Medicine；Mo E Frontiers Science Center for Precision Oncology，University of Macau）.c-MYC-mediated TRIB3/P62+ aggresomes accumulation triggers paraptosis upon the combination of everolimus and ginsenoside Rh2[J].Acta Pharmaceutica Sinica B,2022,第3期
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Fengfeng Li1,2，Man Jiang1,2，Minghui Ma1,2，Xuyang Chen1,2，Yidan Zhang1,2，Yixin Zhang1,2，Yuanyuan Yu1,2，Yunfeng Cui1,2，Jiahui Chen1,2，Hui Zhao1,2，Zhijie Sun3，Deli Dong1,2,3（Department of Pharmacology (the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China，Key Laboratory of Cardiovascular Research，Ministry of Education)，College of Pharmacy，Harbin Medical University；Translational Medicine Research and Cooperation Center of Northern China，Heilongjiang Academy of Medical Sciences，Harbin Medical University；Department of Pharmacology，China Pharmaceutical University）.Anthelmintics nitazoxanide protects against experimental hyperlipidemia and hepatic steatosis in hamsters and mice[J].Acta Pharmaceutica Sinica B,2022,第3期
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Deyan Wu1,2，Xuehua Zheng3，Runduo Liu2，Zhe Li2，Zan Jiang3，Qian Zhou2，Yue Huang2，Xu-Nian Wu2，Chen Zhang2，Yi-You Huang1,2，Hai-Bin Luo1,2（School of Pharmaceutical Sciences，Hainan University；School of Pharmaceutical Sciences，Sun Yat-sen University；School of Pharmaceutical Sciences，Guangzhou Medical University）.Free energy perturbation（FEP）-guided scaffold hopping[J].Acta Pharmaceutica Sinica B,2022,第3期
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Kuan Hu1，Wenyu Wu2，Lin Xie1，Hao Geng3，Yiding Zhang1，Masayuki Hanyu1，Lulu Zhang1，Yinghuan Liu3，Kotaro Nagatsu1，Hisashi Suzuki1，Jialin Guo4，Yundong Wu3,5，Zigang Li3,6，Feng Wang2，Mingrong Zhang1（Department of Advanced Nuclear Medicine Sciences，National Institute of Radiological Sciences，National Institutes for Quantum and Radiological Science and Technology；Department of Nuclear Medicin5，Nanjing First Hospital，Nanjing Medical University；State Key Laboratory of Chemical Oncogenomics，the School of Chemical Biology and Biotechnology，Peking University，Shenzhen Graduate School；Rensselaer Polytechnic Institute；Institute of Chemical Biology；Pingshan Translational Medicine Center）.Whole-body PET tracking of a D-dodecapeptide and its radiotheranostic potential for PD-L1 overexpressing tumors[J].Acta Pharmaceutica Sinica B,2022,第3期
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Cutler T.Lewandowski1，Megan S.Laham2，Gregory R.J.Thatcher2（Department of Pharmaceutical Sciences，University of Illinois College of Pharmacy；Department of Pharmacology and Toxicology，University of Arizona College of Pharmacy）.Remembering your A, B, C’s：Alzheimer’s disease and ABCA1[J].Acta Pharmaceutica Sinica B,2022,第3期
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Qiang Jin1，Jing Jing Wu2，Yue Wu1，Hongxin Li1，Moshe Finel3，Dandan Wang1，Guangbo Ge1（Shanghai Frontiers Science Center of TCM Chemical Biology，Institute of Interdisciplinary Integrative Medicine Research，Shanghai University of Traditional Chinese Medicine；Department of Clinical Pharmacology，College of Pharmacy，Dalian Medical University；Division of Pharmaceutical Chemistry and Technology，Faculty of Pharmacy，University of Helsinki）.Optical substrates for drug-metabolizing enzymes：Recent advances and future perspectives[J].Acta Pharmaceutica Sinica B,2022,第3期
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Yesi Shi1，Hongyan Qian2，Peishi Rao2，Dan Mu1，Yuan Liu2，Gang Liu1，Zhongning Lin1（State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine，School of Public Health，Xiamen University；Department of Rheumatology and Clinical Immunology，The First Affiliated Hospital of Xiamen University）.Bioinspired membrane-based nanomodulators for immunotherapy of autoimmune and infectious diseases[J].Acta Pharmaceutica Sinica B,2022,第3期
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