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期刊文章列表

  • Jinghui Zhang1,2,Jiajun Fan2,3,Xian Zeng2,3,Mingming Nie1,Jingyun Luan2,3,Yichen Wang2,3,Dianwen Ju2,3,Kai Yin1(Department of Gastrointestinal Surgery,Changhai Hospital,Second Military Medical University;Department of Biological Medicines,Fudan University School of Pharmacy;Shanghai Engineering Research Center of Immunotherapeutics).Hedgehog signaling in gastrointestinal carcinogenesis and the gastrointestinal tumor microenvironment[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Tailin He1,Jialin Shang2,Chenglong Gao1,Xin Guan1,Yingyi Chen2,Liwen Zhu3,Luyong Zhang1,Cunjin Zhang3,Jian Zhang2,Tao Pang1(State Key Laboratory of Natural Medicines,Jiangsu Key Laboratory of Drug Screening,Jiangsu Key Laboratory of Drug Discovery for Metabolic Diseases,China Pharmaceutical University;Medicinal Bioinformatics Center,Shanghai Jiao Tong University School of Medicine;Department of Neurology of Drum Tower Hospital,Medical School and the State Key Laboratory of Pharmaceutical Biotechnology,Nanjing University).A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Yuan Fang1,Chao Yang2,Zhiqiang Yu3,Xiaochuan Li4,Qingchun Mu4,Guochao Liao1,Bin Yu5,6(Joint Laboratory for Translational Cancer Research of Chinese Medicine of the Ministry of Education of the People’s Republic of China,International Institute for Translational Chinese Medicine,Guangzhou University of Chinese Medicine;Institute of Innovation & Application,Zhejiang Ocean University;School of Pharmaceutical Sciences,Southern Medical University;The People’s Hospital of Gaozhou;School of Pharmaceutical Sciences,Zhengzhou University;State Key Laboratory of Natural Medicines,China Pharmaceutical University).Natural products as LSD1 inhibitors for cancer therapy[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Panxia Wang1,Minghui Wang1,Yuehuai Hu1,Jianxing Chen1,Yanjun Cao1,Cui Liu1,Zhongkai Wu2,Juan Shen3,Jing Lu1,Peiqing Liu1,4,5(School of Pharmaceutical Sciences,Sun Yat-sen University;Department of Cardiac Surgery,First Affiliated Hospital,Sun Yat-sen University;Guangdong Provincial Key Laboratory of Pharmaceutical Bioactive Substances,Guangdong Pharmaceutical University;Guangdong Provincial Key Laboratory of New Drug Design and Evaluation,Sun Yat-sen University;Guangdong Provincial Engineering Laboratory of Druggability and New Drugs Evaluation).Isorhapontigenin protects against doxorubicin-induced cardiotoxicity via increasing YAP1 expression[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Qiu Sun,Mengyuan Huang,Yuquan Wei(State Key Laboratory of Biotherapy,Cancer Center,West China Hospital,Sichuan University and Collaborative Innovation Center for Biotherapy).Diversity of the reaction mechanisms of SAM-dependent enzymes[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Zhiru Wang1,,,4;Wenting Kang1;Ouwen Li1;Fengyu Qi1;Junwei Wang1;Yinghua You1;Pengxing He1;Zhenhe Suo4;Yichao Zheng1;Hong-Min Liu1(School of Pharmaceutical Sciences,Zhengzhou University;Co-Innovation Center of Henan Province for New Drug R&D and Preclinical Safety;State Key Laboratory of Esophageal Cancer Prevention and Treatment,Key Laboratory of Advanced Drug Preparation Technologies,Ministry of Education of China;Department of Pathology,the Norwegian Radium Hospital,Oslo University Hospital;Department of Pathology,Institute for Clinical Medicine,Faculty of Medicine,University of Oslo).Abrogation of USP7 is an alternative strategy to downregulate PD-L1 and sensitize gastric cancer cells to T cells killing[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Pei Wang1,Fang Wang1,2,3,4,Lan Ni1,Pengfei Wu1,3,Jianguo Chen1,2,3,4(Department of Pharmacology,School of Basic Medicine,Tongji Medical College,Huazhong University of Science and Technology;Key Laboratory of Neurological Diseases (HUST),Ministry of Education of China;The Key Laboratory for Drug Target Researches and Pharmacodynamic Evaluation of Hubei Province;Laboratory of Neuropsychiatric Diseases,the Institute of Brain Research,Huazhong University of Science and Technology).Targeting redox-altered plasticity to reactivate synaptic function:A novel therapeutic strategy for cognitive disorder[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Pingping Luo1,Ming Zheng2,Rui Zhang1,Hong Zhang2,Yingxia Liu3,Wei Li4,Xiaoming Sun5,Qian Yu6,George L.Tipoe6,Jia Xiao1,6(Clinical Medicine Research Institute,the First Affiliated Hospital of Jinan University;Department of Interventional Surgery,the First Affiliated Hospital of Jinan University;State Key Discipline of Infectious Diseases,Department of Infectious Diseases,Shenzhen Third People’s Hospital;Faculty of Pharmaceutical Sciences,Toho University;School of Integrative Pharmacy,Institute of Integrative Pharmaceutical Research,Guangdong Pharmaceutical University;School of Biomedical Sciences,Li Ka Shing Faculty of Medicine,the University of Hong Kong).S-Allylmercaptocysteine improves alcoholic liver disease partly through a direct modulation of insulin receptor signaling[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Peng Liu1,Xin Xie2,Miao Liu1,Shuo Hu3,4,Jinsong Ding1,Wenhu Zhou1,2,4(Xiangya School of Pharmaceutical Sciences,Central South University;School of Pharmaceutical Sciences,Gannan Medical University;Department of Nuclear Medicine,Xiangya Hospital,Central South University;Key Laboratory of Biological Nanotechnology of National Health Commission).A smart MnO2-doped graphene oxide nanosheet for enhanced chemo-photodynamic combinatorial therapy via simultaneous oxygenation and glutathione depletion[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Yihui Song1,Min Zhao1,Yahong Wu2,Bin Yu1,Hong-Min Liu1(School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies,Ministry of Education,Zhengzhou University;School of Life Sciences,Zhengzhou University).A multifunctional cross-validation high-throughput screening protocol enabling the discovery of new SHP2 inhibitors[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Xiaowei Wu1,Mengdi Dai2,3,Rongrong Cui4,Yulan Wang1,Chunpu Li1,Xia Peng2,Jihui Zhao1,3,Bao Wang1,Yang Dai2,Dan Feng1,Tianbiao Yang1,Hualiang Jiang1,4,Meiyu Geng2,Jing Ai2,3,Mingyue Zheng1,3,4,Hong Liu1(State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;Division of Anti-Tumor Pharmacology,State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences;University of Chinese Academy of Sciences;School of Chinese Materia Medica,Nanjing University of Chinese Medicine).Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FGFR inhibitors[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Xianyan Qin1,2,Yingying Xu1,Xu Zhou1,3,Tao Gong1,Zhi-Rong Zhang1,Yao Fu1(Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province,Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology,West China School of Pharmacy,Sichuan University;Key Laboratory of Advanced Technologies of Materials,Ministry of Education and School of Materials Science and Engineering,Southwest Jiaotong University;Sichuan Provincial Orthopedic Hospital).An injectable micelle-hydrogel hybrid for localized and prolonged drug delivery in the management of renal fibrosis[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Yue Gao1,Shicheng Fan1,Hua Li2,Yiming Jiang1,Xinpeng Yao1,Shuguang Zhu2,Xiao Yang1,Ruimin Wang1,Jianing Tian1,Frank J.Gonzalez3,Min Huang1,Huichang Bi1(Guangdong Provincial Key Laboratory of New Drug Design and Evaluation,School of Pharmaceutical Sciences,Sun Yat-sen University;Department of Hepatic Surgery,the Third Affiliated Hospital,Sun Yat-sen University;Laboratory of Metabolism,Center for Cancer Research,National Cancer Institute).Constitutive androstane receptor induced-hepatomegaly and liver regeneration is partially via yes-associated protein activation[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Lei Wang1,2,Mary C.Casey3,Sanjeev Kumar V.Vernekar1,Rajkumar Lalji Sahani1,Karen A.Kirby4,Haijuan Du4,Huanchun Zhang4,Philip R.Tedbury4,Jiashu Xie1,Stefan G.Sarafianos4,Zhengqiang Wang1(Center for Drug Design,College of Pharmacy,University of Minnesota;Department of Pharmaceutical Sciences,School of Chemical Engineering,Dalian University of Technology;Department of Molecular Microbiology and Immunology,University of Missouri School of Medicine,Christopher S.Bond Life Sciences Center;Laboratory of Biochemical Pharmacology,Department of Pediatrics,Emory University School of Medicine).Novel PF74-like small molecules targeting the HIV-1 capsid protein:Balance of potency and metabolic stability[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Ting Zhang1,2,James Zhenggui Tang3,Xiaofan Fei1,Yanping Li4,Yi Song1,Zhiyong Qian5,Qiang Peng2(Department of Pharmacy,West China Hospital,Sichuan University;State Key Laboratory of Oral Diseases,National Clinical Research Center for Oral Diseases,West China Hospital of Stomatology,Sichuan University;Research Institute in Healthcare Science,Faculty of Science and Engineering,School of Pharmacy,University of Wolverhampton;Laboratory of Clinical Pharmacy and Adverse Drug Reaction,West China Hospital of Sichuan University;State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,Sichuan University and Collaborative Innovation Center).Can nanoparticles and nano-protein interactions bring a bright future for insulin delivery?[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Fanxun Zeng1,Shiliang Li2,Guantian Yang1,Yating Luo2,Tiantian Qi2,Yingfan Liang2,Tingyuan Yang2,Letian Zhang1,Rui Wang2,Lili Zhu2,Honglin Li2,Xiaoyong Xu1(Shanghai Key Laboratory of Chemical Biology,School of Pharmacy,East China University of Science &Technology;Shanghai Key Laboratory of New Drug Design,State Key Laboratory of Bioreactor Engineering,School of Pharmacy,East China University of Science & Technology).Design, synthesis, molecular modeling, and biological evaluation of acrylamide derivatives as potent inhibitors of human dihydroorotate dehydrogenase for the treatment of rheumatoid arthritis[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Di Wang1,Danting Li1,Yuxin Zhang2,Jie Chen1,Ying Zhang1,Chuyao Liao1,Siyuan Qin1,Yuan Tian1,Zunjian Zhang1,Fengguo Xu1(Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education),State Key Laboratory of Natural Medicine,China Pharmaceutical University;Nanjing Drum Tower Hospital,the Affiliated Hospital of Nanjing University Medical School).Functional metabolomics reveal the role of AHR/GPR35 mediated kynurenic acid gradient sensing in chemotherapy-induced intestinal damage[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Yamin Gao1,2,3,H.M.Adnan Hameed1,2,3,Yang Liu1,4,Lingmin Guo1,2,3,Cuiting Fang1,2,3,Xirong Tian1,4,Zhiyong Liu1,3,Shuai Wang1,2,3,Zhili Lu1,3,Md Mahmudul Islam1,2,3,Tianyu Zhang1,2,3(State Key Laboratory of Respiratory Disease,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Guangdong-Hong Kong-Macao Joint Laboratory of Respiratory Infectious Diseases,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences;Institute of Physical Science and Information Technology,Anhui University).Ultra-short-course and intermittent TB47-containing oral regimens produce stable cure against Buruli ulcer in a murine model and prevent the emergence of resistance for Mycobacterium ulcerans[J].Acta Pharmaceutica Sinica B,2021,第3期
  • Yuanyuan Chen,Zhaojun Li,Xiaoguang Chen,Sen Zhang(State Key Laboratory of Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences,Peking Union Medical College).Long non-coding RNAs:From disease code to drug role[J].Acta Pharmaceutica Sinica B,2021,第2期
  • David Dolivo1,Pamela Weathers2,Tanja Dominko2(Department of Surgery,Northwestern University-Feinberg School of Medicine;Department of Biology and Biotechnology,Worcester Polytechnic Institute).Artemisinin and artemisinin derivatives as anti-fibrotic therapeutics[J].Acta Pharmaceutica Sinica B,2021,第2期
  • Jianfeng Wang1,Xiaomao Yin1,Wei He2,Wei Xue1,Jin Zhang1,Yiran Huang1(Department of Urology,Renji Hospital,School of Medicine,Shanghai Jiao Tong University;Department of Pathology,Renji Hospital,School of Medicine,Shanghai Jiao Tong University).SUV39H1 deficiency suppresses clear cell renal cell carcinoma growth by inducing ferroptosis[J].Acta Pharmaceutica Sinica B,2021,第2期
  • Xu Jing1,2,Dandan Ren1,3,Fei Gao2,Ye Chen1,Xiao Wu4,Yue Han1,Qingsheng Han1,Liang Li1,Xiaojie Wang1,Wei Tang5,Yan Zhang1(Department of Pharmacology,School of Basic Medical Science,Shandong University;Department of Clinical Laboratory,the Second Hospital of Shandong University;Chengda Biology Co.,Ltd.;The Key Laboratory of Cardiovascular Remodeling and Function Research,Department of Cardiology,Qilu Hospital of Shandong University;Department of Microbiology,School of Basic Medical Science,Shandong University).Gene deficiency or pharmacological inhibition of PDCD4-mediated FGR signaling protects against acute kidney injury[J].Acta Pharmaceutica Sinica B,2021,第2期
  • Zhiming Zhangy,Chenlu Huangy,Li Zhang,Qing Guo,Yu Qin,Fan Fan,Boxuan Li,Bao Xiao,Dunwan Zhu,Linhua Zhang(Tianjin Key Laboratory of Biomedical Materials,Key Laboratory of Biomaterials and Nanotechnology for Cancer Immunotherapy,Institute of Biomedical Engineering,Chinese Academy of Medical Sciences & Peking Union Medical College).pH-sensitive and bubble-generating mesoporous silica-based nanoparticles for enhanced tumor combination therapy[J].Acta Pharmaceutica Sinica B,2021,第2期
  • Qian Wei1,Jian Bai1,Daojiang Yan1,Xiuqi Bao1,Wenting Li2,Bingyu Liu1,Dan Zhang1,Xiangbing Qi2,Dequan Yu1,Youcai Hu1(State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences & Peking Union Medical College;National Institute of Biological Sciences).Genome mining combined metabolic shunting and OSMAC strategy of an endophytic fungus leads to the production of diverse natural products[J].Acta Pharmaceutica Sinica B,2021,第2期
  • Tingting Jiang1,Guan Wang1,Yao Liu1,Lu Feng1,Meng Wang1,Jie Liu1,Yi Chen2,Liang Ouyang1(State Key Laboratory of Biotherapy and Cancer Center,West China Hospital,and Collaborative Innovation Center of Biotherapy,Sichuan University;State Key Laboratory of Biotherapy and Cancer Center and Department of Gastrointestinal Surgery,West China Hospital,Sichuan University,and Collaborative Innovation Center for Biotherapy).Development of small-molecule tropomyosin receptor kinase(TRK) inhibitors for NTRK fusion cancers[J].Acta Pharmaceutica Sinica B,2021,第2期
  • Shaojun Peng1,2,Boshu Ouyang3,Yongjie Xin1,Wei Zhao1,Shun Shen4,Meixiao Zhan1,Ligong Lu1(Zhuhai Precision Medical Center,Zhuhai Interventional Medical Center,Zhuhai People’s Hospital(Zhuhai Hospital Affiliated with Jinan University);The Institute for Translational Nanomedicine,Shanghai East Hospital,Tongji University School of Medicine;Central Laboratory,First Affiliated Hospital,Institute of Integrative Medicine,Dalian Medical University;Zhejiang Cancer Hospital,Institute (College) of Cancer Research).Hypoxia-degradable and long-circulating zwitterionic phosphorylcholine-based nanogel for enhanced tumor drug delivery[J].Acta Pharmaceutica Sinica B,2021,第2期
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