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Zhang-Chao Deng1,Jia-Cheng Yang1,Yu-Xuan Huang1,Ling Zhao1,Jinshui Zheng1,Qing-Biao Xu1,Leluo Guan2,Lv-Hui Sun1(State Key Laboratory of Agricultural Microbiology,Hubei Hongshan Laboratory,Frontiers Science Center for Animal Breeding and Sustainable Production,College of Animal Science and Technology,Huazhong Agricultural University;Department of Agricultural,Food and Nutritional Science,University of Alberta).Translocation of gut microbes to epididymal white adipose tissue drives lipid metabolism disorder under heat stress[J].Science China(Life Sciences),2023,第12期
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Yachun Yang1,2,Cheng Zhang2,3,4,Hao Li1,2,Zeyuan Yang3,4,Zuntao Xu1,2,3,4,Dewei Tai1,2,Dahu Ni1,Pengcheng Wei1,Chengxin Yi1,Jianbo Yang1,Yong Ding2,3,4(Rice Research Institute,Anhui Academy of Agricultural Sciences;Institute of Health and Medicine,Hefei Comprehesive National Science Center;Ministry of Education Key Laboratory for Membraneless Organelles and Cellular Dynamics;School of Life Sciences,Division of Life Sciences and Medicine,University of Science and Technology of China).An epi-allele of SMS causes Sanming dominant genic male sterility in rice[J].Science China(Life Sciences),2023,第12期
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Xinyue Li1,Meina Quan1,2,Yiping Wei1,Wei Wang1,2,Lingzhi Xu1,Qi Wang1,2,Jianping Jia1,2,3,4,5,6(Innovation Center for Neurological Disorders and Department of Neurology,Xuanwu Hospital,Capital Medical University;National Medical Center for Neurological Diseases and National Clinical Research Center for Geriatric Diseases;Beijing Key Laboratory of Geriatric Cognitive Disorders;Clinical Center for Neurodegenerative Disease and Memory Impairment,Capital Medical University;Center of Alzheimer's Disease,Beijing Institute of Brain Disorders,Collaborative Innovation Center for Brain Disorders,Capital Medical University;Key Laboratory of Neurodegenerative Diseases,Ministry of Education).Critical thinking of Alzheimer’s transgenic mouse model:current research and future perspective[J].Science China(Life Sciences),2023,第12期
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Jinsong Wang1,Wenna Wang1,2,Fei Ma1,2,Haili Qian1(State Key Laboratory of Molecular Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Medical Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College).A hidden translatome in tumors——the coding lncRNAs[J].Science China(Life Sciences),2023,第12期
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Zhengyang Guo1,Xiao Huo1,Xianlong Li1,Changtao Jiang1,2,Lixiang Xue1,3(Center of Basic Medical Research,Institute of Medical Innovation and Research,Peking University Third Hospital;Department of Physiology and Pathophysiology,School of Basic Medical Sciences,Peking University and the Key Laboratory of Molecular Cardiovascular Science(Peking University),Ministry of Education;Peking University Third Hospital Cancer Center,Department of Radiation Oncology,Peking University Third Hospital).Advances in regulation and function of stearoyl-CoA desaturase 1 in cancer, from bench to bed[J].Science China(Life Sciences),2023,第12期
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Shuting Yu1,ZhiYong Sun1,Xiuzhu Wang1,Tiantian Ju1,Changhao Wang1,Yingqi Liu1,Zhezhe Qu1,KuiWu Liu1,Zhongting Mei1,Na Li1,Meixi Lu2,Fan Wu1,Min Huang1,Xiaochen Pang1,Yingqiong Jia1,Ying Li1,Yaozhi Zhang1,Shunkang Dou1,Jianhao Jiang1,Xin Li1,Baofeng Yang1,3,4,Weijie Du1,3,4(Department of Pharmacology(The State-Province Key Laboratories of Biomedicine Pharmaceutics of China,Key Laboratory of Cardiovascular Research,Ministry of Education),College of Pharmacy,Harbin Medical University;Traditional Chinese Medicine School,Beijing University of Chinese Medicine;Northern Translational Medicine Research and Cooperation Center,Heilongjiang Academy of Medical Sciences,Harbin Medical University;Research Unit of Noninfectious Chronic Diseases in Frigid Zone,Chinese Academy of Medical Sciences).Mettl13 protects against cardiac contractile dysfunction by negatively regulating C-Cbl-mediated ubiquitination of SERCA2a in ischemic heart failure[J].Science China(Life Sciences),2023,第12期
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Guanglei Chen1,Lisha Sun1,Xi Gu1,Liping Ai1,Jie Yang1,Zhan Zhang1,Pengjie Hou1,Yining Wang1,Xunyan Ou1,Xiaofan Jiang1,Xinbo Qiao1,Qingtian Ma1,Nan Niu1,Jinqi Xue1,Hao Zhang1,Yongliang Yang2,Caigang Liu1(Department of Oncology,Cancer Stem Cell and Translation Medicine Lab,Innovative Cancer Drug Research and Development Engineering Center of Liaoning Province,Shengjing Hospital of China Medical University;School of Bioengineering,Dalian University of Technology).FSIP1 enhances the therapeutic sensitivity to CDK4/6 inhibitors in triple-negative breast cancer patients by activating the Nanog pathway[J].Science China(Life Sciences),2023,第12期
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Longzhong Jia1,Wenji Wang1,2,Jing Liang1,Shudong Niu1,Yibo Wang1,Jian Yang1,Lingyu Li1,Ge Wang1,Xueqiang Xu1,Lu Mu1,Kaixin Cheng1,Xuebing Yang1,Yijing Wang3,Haoshu Luo1,Guoliang Xia1,4,Yuwen Ke1,Yan Zhang1,Hua Zhang1(State Key Laboratory of Animal Biotech Breeding,College of Biological Sciences,China Agricultural University;School of Life Sciences,Taizhou University;National Institute of Biological Sciences;Key Laboratory of Ministry of Education for Conservation and Utilization of Special Biological Resources in Western China,College of Life Science,Ningxia University).Analyzing the cellular and molecular atlas of ovarian mesenchymal cells provides a strategy against female reproductive aging[J].Science China(Life Sciences),2023,第12期
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Jian Wu1,Caixia Lin2,Chenlong Yang3,4,Lijie Pan1,Hongyi Liu1,Sirui Zhu1,Shuwen Wei1,Xu Jia5,Qi Zhang5,Ziyu Yu6,Xiaofang Zhao3,Weihai Liu3,Yehong Zhuo5,Ningli Wang1(Beijing Institute of Ophthalmology,Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University,Beijing Key Laboratory of Ophthalmology and Visual Sciences;Beijing Tongren Eye Center,Beijing Tongren Hospital,Capital Medical University;Department of Neurosurgery,Peking University Third Hospital,Center for Precision Neurosurgery and Oncology of Peking University Health Science Center;North America Medical Education Foundation;State Key Laboratory of Ophthalmology,Zhongshan Ophthalmic Center,Sun Yat-sen University;Spencer Center for Vision Research,Byers Eye Institute,School of Medicine,Stanford University).Identification and validation of key biomarkers and potential therapeutic targets for primary open-angle glaucoma[J].Science China(Life Sciences),2023,第12期
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Yanan Qi1,2,3,Ying Zhang1,3,4,Shuangjie Tian1,2,3,Ruojun Zong1,2,3,Xinghui Yan1,2,3,Yu Wang1,2,3,Yanfang Wang5,6,Jianguo Zhao1,2,3,4(State Key Laboratory of Stem Cell and Reproductive Biology,Institute of Zoology,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Institute for Stem Cell and Regeneration,Chinese Academy of Sciences;Beijing Institute for Stem Cell and Regenerative Medicine;State Key Laboratory of Animal Nutrition,Institute of Animal Science,Chinese Academy of Agricultural Sciences;Guangdong Laboratory for Lingnan Modern Agriculture).An optimized prime editing system for efficient modification of the pig genome[J].Science China(Life Sciences),2023,第12期
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Qingzhuo Zhang1,Siyuan Chen1,Yan Guo1,Fang He2,Jian Fu1,Wenkai Ren1(Guangdong Laboratory of Lingnan Modern Agriculture,National Engineering Research Center for Breeding Swine Industry,College of Animal Science,South China Agricultural University;College of Animal Science and Technology,Southwest University).Phenylalanine diminishes M1 macrophage inflammation[J].Science China(Life Sciences),2023,第12期
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Lei Yin1,Zhenggao Zheng1,Yilin Li1,Xiying Li1,Dan Cheng1,Chunxia Dong1,Yixuan Liu2,Jindong Zhao1,3(State Key Laboratory of Protein and Plant Genetic Engineering,School of Life Sciences,Peking University;National Teaching Center for Experimental Biology,School of Life Sciences,Peking University;Institute of Hydrobiology,Chinese Academy of Sciences).PatU3 plays a central role in coordinating cell division and differentiation in pattern formation of filamentous cyanobacterium Nostoc sp. PCC 7120[J].Science China(Life Sciences),2023,第12期
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Jianduo Zhang1,Lu Zhang2,Chengwei Zhang2,Yongxing Yang2,Huayin Liu3,Lu Li2,Shengxue Zhang4,Xianggan Li4,Xinxiang Liu2,Ya Liu2,Jin Wang1,Guangyu Yang1,Qingyou Xia5,Weiguang Wang3,Jinxiao Yang2(Yunnan Key Laboratory of Tobacco,Yunnan Academy of Tobacco Science;Beijing Key Laboratory of Maize DNA Fingerprinting and Molecular Breeding,Beijing Academy of Agriculture & Forestry Sciences;Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal Endophytes,State Ethnic Affairs Commission,Yunnan Minzu University;Cropedit Biotechnology Co.Ltd.;Biological Science Research Center,Southwest University).Developing an efficient and visible prime editing system to restore tobacco 8-hydroxy-copalyl diphosphate gene for labdane diterpene Z-abienol biosynthesis[J].Science China(Life Sciences),2023,第12期
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Yutong Liu1,Xiaoyuan Peng1,Ao Ma1,Wenxin Liu1,Bao Liu1,Dae-Jin Yun1,2,Zheng-Yi Xu1(Key Laboratory of Molecular Epigenetics of the Ministry of Education(MOE),Northeast Normal University;Department of Biomedical Science and Engineering,Konkuk University).Type-B response regulator OsRR22 forms a transcriptional activation complex with OsSLR1 to modulate OsHKT2;1 expression in rice[J].Science China(Life Sciences),2023,第12期
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Cong Sun1,Yuan-Tao Liu1,Yin-Feng Kang1,Chu Xie1,Shu-Xin Li1,Yu-Tong Lu2,Mu-Sheng Zeng1(State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy,Department of Experimental Research,Sun Yat-sen University Cancer Center,Sun Yat-sen University;National Supercomputer Center in Guangzhou,School of Computer Science and Engineering,Sun Yat-sen University).Elucidation of the neutralizing antibody evasion of emergent SARS-CoV-2 Omicron sub-lineages using structural analysis[J].Science China(Life Sciences),2023,第12期
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Yuxuan Guo1,2,3,4,Yangpo Cao9,Blake D.Jardin9,Neil Mazumdar9,Congting Guo1,2,Luzi Yang1,2,Junsen Lin1,2,Zhan Chen1,2,Qing Ma9,Mingming Zhao6,7,Erdan Dong2,3,4,6,7,8,William T.Pu9,10(Peking University Health Science Center,School of Basic Medical Sciences;Peking University Institute of Cardiovascular Sciences;State Key Laboratory of Vascular Homeostasis and Remodeling,Peking University;Beijing Key Laboratory of Cardiovascular Receptors Research;Boston Children’s Hospital,Department of Cardiology;Peking University Third Hospital,Department of Cardiology and Institute of Vascular Medicine;Research Unit of Medical Science Research Management/Basic and Clinical Research of Metabolic Cardiovascular Diseases,Chinese Academy of Medical Sciences,Haihe Laboratory of Cell Ecosystem;National Health Commission Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides;Boston Children's Hospital,Department of Cardiology;Harvard Stem Cell Institute).A shared role of the myocardin-family transcriptional coactivators in cardiomyocyte maturation[J].Science China(Life Sciences),2023,第12期
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Lei Duan1,2,Lin Fu1,2,Hong-Feng Chen1,2(Key Laboratory of Plant Resources Conservation and Sustainable Utilization,South China Botanical Garden,Chinese Academy of Sciences;South China National Botanical Garden).Phylogenomic cytonuclear discordance and evolutionary histories of plants and animals[J].Science China(Life Sciences),2023,第12期
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Hongyuan Zheng1,Junyao Zhao1,Daowen Wang1,Zheng Qing Fu2(State Key Laboratory of Wheat and Maize Crop Science,College of Agronomy,Center for Crop Genome Engineering,Henan Agricultural University;Department of Biological Sciences,University of South Carolina).Rising from the dead:the power of genome editing[J].Science China(Life Sciences),2023,第12期
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Guozhi Bi1,Jian-Min Zhou2(State Key Laboratory of Plant Environmental Resilience,College of Biological Sciences,China Agricultural University;State Key Laboratory of Plant Genomics,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences).Effector modularity promotes functional diversification and evolutionary processes[J].Science China(Life Sciences),2023,第12期
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Zekai Wu,Tianru Jin,Jianping Weng.Erratum to:A thorough analysis of diabetes research in China from 1995 to 2015:current scenario and future scope[J].Science China Life Sciences,2023,第12期
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Yuxuan Zheng1,George F.Gao1,2(CAS Key Laboratory of Pathogen Microbiology and Immunology,Institute of Microbiology,Chinese Academy of Sciences;Savaid Medical School,University of the Chinese Academy of Sciences).Geneformer:a deep learning model for exploring gene networks[J].Science China(Life Sciences),2023,第12期
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(Department of Pharmacology(The State-Province Key Laboratories of Biomedicine Pharmaceutics of China,Key Laboratory of Cardiovascular Research,Ministry of Education),College of Pharmacy,Harbin Medical University,Harbin 150081,China;Traditional Chinese Medicine School,Beijing University of Chinese Medicine,Beijing 100029,China;Department of Pharmacology(The State-Province Key Laboratories of Biomedicine Pharmaceutics of China,Key Laboratory of Cardiovascular Research,Ministry of Education),College of Pharmacy,Harbin Medical University,Harbin 150081,China;Northern Translational Medicine Research and Cooperation Center,Heilongjiang Academy of Medical Sciences,Harbin Medical University,Harbin 150081,China;Research Unit of Noninfectious Chronic Diseases in Frigid Zone,Chinese Academy of Medical Sciences,2019RU070,Harbin 150081,China).Mettl13 protects against cardiac contractile dysfunction by negatively regulating C-Cb1-mediated ubiquitination of SERCA2a in ischemic heart failure[J].中国科学(生命科学)(英文版),2023,第12期
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Fengming Huang,Jiaqi Liu,Sifen Du,Yexuan Lin,Chengyu Jiang(State Key Laboratory of Common Mechanism Research for Major Diseases,Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences,Department of Biochemistry,School of Basic Medicine Peking Union Medical College).Potential oligonucleotide drugs in Bencao sRNA Atlas[J].Science China(Life Sciences),2023,第12期
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Yian Wang1,2,3,Qijia Yan4,Chunmei Fan2,Yongzhen Mo2,Yumin Wang4,Xiayu Li3,Qianjin Liao1,Can Guo2,Guiyuan Li1,2,3,Zhaoyang Zeng1,2,Wei Xiong1,2,3,He Huang1,2,3(NHC Key Laboratory of Carcinogenesis and Hunan Key Laboratory of Cancer Metabolism,Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine,Central South University;Key Laboratory of Carcinogenesis and Cancer Invasion of the Chinese Ministry of Education,Cancer Research Institute,Central South University;Hunan Key Laboratory of Nonresolving Inflammation and Cancer,Disease Genome Research Center,The Third Xiangya Hospital,Central South University;Department of Otolaryngology Head and Neck Surgery,Xiangya Hospital,Central South University).Overview and countermeasures of cancer burden in China[J].Science China(Life Sciences),2023,第11期
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Xuefei Wang1,2,Chen Chen3,4,Hongwei Sun,Kaiqiong Mao2,Jiameng Yao2,Weiqiao Zhang3,Meixiao Zhan,Hua-Bing Li1,2,Zhiren Zhang,Shu Zhu3,4,Ligong Lu(Department of Geriatrics,Medical Center on Aging of Ruijin Hospital,Shanghai Jiao Tong University School of Medicine;Shanghai Institute of Immunology,State Key Laboratory of Oncogenes and Related Genes,Shanghai Jiao Tong University School of Medicine;Institute of Immunology,The CAS Key Laboratory of Innate Immunity and Chronic Disease,Division of Life Sciences and Medicine,University of Science and Technology of China;Institute of Health and Medicine,Hefei Comprehensive National Science Center;Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment,Zhuhai Interventional Medical Center,Zhuhai People’s Hospital (Zhuhai Hospital Affiliated with Jinan University)).m~6A mRNA modification potentiates Th17 functions to inflame autoimmunity[J].Science China(Life Sciences),2023,第11期
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Siyu Yang,Dong Chen,Lei Xie,Xiaoxiao Zou,Yanyuan Xiao,Lin Rao,Tianxiong Yao,Qing Zhang,Liping Cai,Fei Huang,Bin Yang,Lusheng Huang(State Key Laboratory of Pig Genetic Improvement and Production Technology,Jiangxi Agricultural University).Developmental dynamics of the single nucleus regulatory landscape of pig hippocampus[J].Science China(Life Sciences),2023,第11期
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Xinrui Fan,Xinwen Yan,Shuo Han(State Key Laboratory of Molecular Biology,CAS Center for Excellence in Molecular Cell Science,Shanghai Institute of Biochemistry and Cell Biology,Chinese Academy of Sciences).Enzyme-mediated proximity labeling for mapping molecular interactions[J].Science China(Life Sciences),2023,第11期
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Shaomin Liu1,Fengqian Zhang2,Yixia Liang2,Guo Wu3,Rong Liu3,Xiuling Li2,Phei Er Saw2,Zhonghan Yang1(Department of Biochemistry,Molecular Cancer Research Center,School of Medicine,Sun Yat-sen University;Nanhai Translational Innovation Center of Precision Immunology,Sun Yat-sen Memorial Hospital;Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study,Institute of Pharmacy & Pharmacology,School of Pharmaceutical Science,University of South China).Nanoparticle(NP)-mediated APOC1 silencing to inhibit MAPK/ERK and NF-κB pathway and suppress breast cancer growth and metastasis[J].Science China(Life Sciences),2023,第11期
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Lijuan Fan1,Yaoyao Xia1,Youxia Wang1,Dandan Han2,Yanli Liu3,Jiahuan Li4,Jie Fu5,Leli Wang6,Zhending Gan1,Bingnan Liu1,Jian Fu1,Congrui Zhu1,Zhenhua Wu2,Jinbiao Zhao2,Hui Han7,Hao Wu4,Yiwen He6,8,Yulong Tang6,Qingzhuo Zhang1,Yibin Wang3,Fan Zhang3,Xin Zong5,Jie Yin9,Xihong Zhou6,Xiaojun Yang3,Junjun Wang2,Yulong Yin6,9,Wenkai Ren1(Guangdong Laboratory of Lingnan Modern Agriculture,National Engineering Research Center for Breeding Swine Industry,College of Animal Science,South China Agricultural University;State Key Laboratory of Animal Nutrition,College of Animal Science and Technology,China Agricultural University;College of Animal Science and Technology,Northwest A&F University;State Key Laboratory of Agricultural Microbiology,College of Veterinary Medicine,Huazhong Agricultural University;College of Animal Sciences,Zhejiang University;Key Laboratory of Agro-ecological Processes in Subtropical Region,Institute of Subtropical Agriculture,Chinese Academy of Sciences;Institute of Animal Sciences,Chinese Academy of Agricultural Sciences;Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation,College of Life Sciences,Hunan Normal University;College of Animal Science and Technology,Hunan Agricultural University).Gut microbiota bridges dietary nutrients and host immunity[J].Science China(Life Sciences),2023,第11期
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