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Ye Huiyun,Song Yali,Ye Wenting,Xiong Chongxiang,Li Jiemei,Miao Jinhua,Shen Weiwei,Li Xiaolong,Zhou Lili.Serum granulosa cell-derived TNF-alpha promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-kappaB signaling[J].中国药理学报,2023,第12期
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Xiao-jiao-yang Li,Fei Zhou,Ya-jing Li,Xiao-yong Xue,Jiao-rong Qu,Gui-fang Fan,Jia Liu,Rong Sun,Jian-zhi Wu,Qi Zheng,Run-ping Liu(School of Life Sciences,Beijing University of Chinese Medicine,Beijing 100029,China;School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 100029,China;The Second Hospital of Shandong University,Ji-nan 250033,China).LncRNA H19-EZH2 interaction promotes liver fibrosis via reprogramming H3K27me3 profiles[J].中国药理学报(英文版),2023,第12期
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Tian-tian Liu,Huan-huan Xu,Ze-juan Liu,He-ping Zhang,Hai-tao Zhou,Zhi-Xiang Zhu,Zhi-qiang Wang,Jing-yi Xue,Qiang Li,Yi Ma,Hong-jie You,Da-li Luo(Department of Pharmacology,Beijing Key Laboratory of Cardiovascular Diseases Related to Metabolic Disturbance,Capital Medical University,Beijing 100069,China;Beijing Friendship Hospital,The Affiliated Hospital of Capital Medical University,Beijing 100065,China;National Cancer Center,National Clinical Research Center for Cancer,Cancer Hospital,and Peaking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100021,China).Downregulated calmodulin expression contributes to endothelial cell impairment in diabetes[J].中国药理学报(英文版),2023,第12期
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Juan-min Li,Hai-shan Deng,Yun-da Yao,Wei-ting Wang,Jia-qin Hu,Yan Dong,Pei-xun Wang,Liang Liu,Zhong-qiu Liu,Ying Xie,Lin-lin Lu,Hua Zhou(International Institute for Translational Chinese Medicine,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;State Key Laboratory of Traditional Chinese Medicine Syndrome,Guangdong Provincial Hospital of Chinese Medicine,Guangdong Provincial Academy of Chinese Medical Sciences,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Faculty of Chinese Medicine and State Key Laboratory of Quality Research in Chinese Medicine,Macau University of Science and Technology,Taipa,Macao,China;Science and Technology Innovation Center,Guangzhou University of Chinese Medicine,Guangzhou 510405,China;State Key Laboratory of Traditional Chinese Medicine Syndrome,Guangdong Provincial Hospital of Chinese Medicine,Guangdong Provincial Academy of Chinese Medical Sciences,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510006,China;International Institute for Translational Chinese Medicine,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;State Key Laboratory of Traditional Chinese Medicine Syndrome,Guangdong Provincial Hospital of Chinese Medicine,Guangdong Provincial Academy of Chinese Medical Sciences,The Second Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510006,China).Sinomenine ameliorates collagen-induced arthritis in mice by targeting GBP5 and regulating the P2X7 receptor to suppress NLRP3-related signaling pathways[J].中国药理学报(英文版),2023,第12期
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Shuai Wang,Yu-fei Wang,Guang Yang,Hui-hui Zhang,Hong-feng Yuan,Chun-yu Hou,Li-na Zhao,Yu-hongSuo,Jiao Sun,Lin-lin Sun,Pan Lv,Yan Sun,Ning-ning Zhang,Xiao-dong Zhang,Wei Lu(Department of Hepatobiliary Oncology,Liver Cancer Center,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Tianjin's Clinical Research Center for Cancer,Key Laboratory of Cancer Prevention and Therapy,Tianjin Medical University,Tianjin 300060,China;Department of Gastrointestinal Cancer Biology,Tianjin Cancer Institute,Tianjin Medical University Cancer Institute,and Hospital,National Clinical Research Center for Cancer,Tianjin 300060,China;Department of Pathology,Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer,National Clinical Research Center for Cancer,Tianjin Cancer Institute and Hospital,Tianjin Medical University,Tianjin 300060,China).Heat shock protein family A member 8 serving as a co-activator of transcriptional factor ETV4 up-regulates PHLDA2 to promote the growth of liver cancer[J].中国药理学报(英文版),2023,第12期
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Wa Ding,Jin-xiang Wang,Jun-zheng Wu,Ao-chu Liu,Li-IingJiang,Hai-chuan Zhang,Yi Meng,Bing-yuan Liu,Guan-jie Peng,En-zhe Lou,Qiong Mao,Huan Zhou,Dao-lin Tang,Xin Chen,Jin-bao Liu,Xian-ping Shi(The Sixth Affiliated Hospital of Guangzhou Medical University,Qingyuan People's Hospital,Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation,Sino-French Hoffmann Institute,School of Basic Medical Sciences,Guangzhou Medical University,Qingyuan 511500,China;Guangdong Provincial Education Department Key Laboratory of Nano-Immunoregulation Tumour Microenvironment,The Second Affiliated Hospital,Guangzhou Medical University,Guangzhou 510260,China;Guangdong Provincial Key Laboratory of Digestive Cancer Research,Digestive Diseases Center,Precision Medicine Center,Department of Biobank,The Seventh Affiliated Hospital,Sun Yat-Sen University,Shenzhen 518107,China;The Sixth Affiliated Hospital of Guangzhou Medical University,Qingyuan People's Hospital,Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation,Sino-French Hoffmann Institute,School of Basic Medical Sciences,Guangzhou Medical University,Qingyuan 511500,China;Department of Surgery,UT Southwestern Medical Center,Dallas,TX 75390,USA).Targeting proteasomal deubiquitinases USP14 and UCHL5 with b-AP15 reduces 5-fluorouracil resistance in colorectal cancer cells[J].中国药理学报(英文版),2023,第12期
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Yuan-dong Zheng,Hua Zhang,Yan Zhan,Yi-cong Bian,Sheng Ma,Hai-xian Gan,Xiao-juan Lai,Yong-qiang Liu,Yan-chun Gong,Xue-fang Liu,Hong-bin Sun,Yong-guo Li,Da-fang Zhong,Li-yan Miao,Xing-xing Diao.Author Correction:Pharmacokinetics,mass balance,and metabolism of [14C]vicagrel,a novel irreversible P2Y12 inhibitor in humans[J].中国药理学报(英文版),2023,第12期
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Kai-long Jiang,Chang-mei Liu,Li-tong Nie,Hai-ni Jiang,Lei Xu,Kun-zhi Zhang,Li-xia Fan,An-hui Gao,Lu-lin Lin,Xiang-yu Wang,Min-jia Tan,Qi-qing Zhang,Yu-bo Zhou,Jia Li.Author Correction:Discovery of toxoflavin,a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition[J].中国药理学报(英文版),2023,第12期
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Qian Cao,Xin Du,Xiao-yan Jiang,Yuan Tian,Chen-hao Gao,Zi-yu Liu,Ting Xu,Xing-xing Tao,Ming Lei,Xiao-qiang Wang,Lingyu Linda Ye,Dayue Darrel Duan(Center for Phenomics of Traditional Chinese Medicine,the Affiliated Traditional Chinese Medicine Hospital,Southwest Medical University,Luzhou 646000,China;Center for Phenomics of Traditional Chinese Medicine,the Affiliated Traditional Chinese Medicine Hospital,Southwest Medical University,Luzhou 646000,China;Institute of Integrated Chinese and Western Medicine,Southwest Medical University,Luzhou 646000,China;Key Laboratory of Autoimmune Diseases and Precision Medicie,People's Hospital of Ningxia Hui Autonomous Region,Yinchuan 750001,China;Center for Phenomics of Traditional Chinese Medicine,the Affiliated Traditional Chinese Medicine Hospital,Southwest Medical University,Luzhou 646000,China;Institute of Integrated Chinese and Western Medicine,Southwest Medical University,Luzhou 646000,China;Key Laboratory of Autoimmune Diseases and Precision Medicie,People's Hospital of Ningxia Hui Autonomous Region,Yinchuan 750001,China;The Department of Pharmacology,University of Nevada Reno School of Medicine,Reno,NV 89557,USA).Phenome-wide association study and precision medicine of cardiovascular diseases in the post- COVID-19 era[J].中国药理学报(英文版),2023,第12期
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Mei Jin,Jian Fang,Jiao-jiao Wang,Xin Shao,Suo-wen Xu,Pei-qing Liu,Wen-cai Ye,Zhi-ping Liu(Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research,College of Pharmacy,Jinan University,Guangzhou 511436,China;Affiliated Huadu Hospital,Southern Medical University(People's Hospital of Huadu District),Guangzhou 510800,China;Department of Food Science and Engineering,Jinan University,Guangzhou 511436,China;Institute of Endocrine and Metabolic Diseases,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230026,China;Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research,College of Pharmacy,Jinan University,Guangzhou 511436,China;National-Local Joint Engineering Lab of Druggability and New Drugs Evaluation,Guangdong Provincial Key Laboratory of New Drug Design and Evaluation,Sun Yat-sen University,Guangzhou 510006,China).Regulation of toll-like receptor(TLR)signaling pathways in atherosclerosis:from mechanisms to targeted therapeutics[J].中国药理学报(英文版),2023,第12期
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Jia-ling Ji,Hui-min Shi,Zuo-lin Li,Ran Jin,Gao-ting Qu,Hui Zheng,E.Wang,Yun-yang Qiao,Xing-yue Li,Ling Ding,Da-fa Ding,Liu-cheng Ding,Wei-hua Gan,Bin Wang,Ai-qing Zhang(Department of Pediatric Nephrology,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210003,China;Institute of Nephrology,Zhong Da Hospital,Southeast University School of Medicine,Nanjing 210009,China;Department of Pediatrics,the Fourth Affiliated Hospital of Nanjing Medical University,Nanjing 210031,China;Department of Endocrinology,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210003,China;Department of Urology,the Second Affiliated Hospital of Nanjing Medical University,Nanjing 210003,China).Satellite cell-derived exosome-mediated delivery of microRNA-23a/27a/26a cluster ameliorates the renal tubulointerstitial fibrosis in mouse diabetic nephropathy[J].中国药理学报(英文版),2023,第12期
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Jie Wang,Mei Bai,Cui Zhang,Ning An,Li Wan,Xiao-ning Wang,Rong-hui Du,Yan Shen,Zhi-yao Yuan,Xu-dong Wu,Xue-feng Wu,Qiang Xu(State Key Laboratory of Pharmaceutical Biotechnology,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210000,China;School of Basic Medical Sciences,Nanjing Medical University,Nanjing 210000,China;State Key Laboratory of Pharmaceutical Biotechnology,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210000,China;State Key Laboratory of Pharmaceutical Biotechnology,Nanjing Drum Tower Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210000,China;Department of Periodontology,Nanjing Stomatological Hospital,Affiliated Hospital of Medical School,Nanjing University,Nanjing 210000,China).Natural compound fraxinellone ameliorates intestinal fibrosis in mice via direct intervention of HSP47-collagen interaction in the epithelium[J].中国药理学报(英文版),2023,第12期
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Hui-yun Ye,Ya-li Song,Wen-ting Ye,Chong-xiang Xiong,Jie-mei Li,Jin-hua Miao,Wei-wei Shen,Xiao-long Li,Li-li Zhou(Division of Nephrology,Nanfang Hospital,Southern Medical University,National Clinical Research Center for Kidney Disease,State Key Laboratory of Organ Failure Research,Guangdong Provincial Institute of Nephrology,Guangdong Provincial Key Laboratory of Renal Failure Research,Guangzhou 510515,China;Center for Reproductive Medicine,Dongguan Maternal and Child Health Care Hospital,Southern Medical University,Dongguan 523057,China;Division of Nephrology,Dongguan First Hospital of Guangdong Medical University,Dongguan 523710,China).Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling[J].中国药理学报(英文版),2023,第12期
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Tian-tian Wang,Li-chun Zhang,Zhen Qin,Shu-jun Chen,Jing-min Zeng,Jing-yan Li,Lin An,Cai-yanWang,Yong Gao,Li-ming Wang,Zhong-xiang Zhao,Zhong-qiu Liu,Shao-gui Wang(International Institute for Translational Chinese Medicine,School of Pharmaceutical Sciences,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Guangdong Provincial Key Laboratory of Translational Cancer Research of Chinese Medicines,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Joint International Research Laboratory of Translational Cancer Research of Chinese Medicines,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;Science and Technology Innovation Center,Guangzhou University of Chinese Medicine,Guangzhou 510006,China;School of Biomedical Science,Hunan University,Changsha 410082,China).Decreased syntaxin17 expression contributes to the pathogenesis of acute pancreatitis in murine models by impairing autophagic degradation[J].中国药理学报(英文版),2023,第12期
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Lin Yang,Qi Zhang,Xue-qing Wu,Xiao-yun Qiu,Fan Fei,Nan-xi Lai,Yu-yi Zheng,Meng-di Zhang,Qing-yang Zhang,Yu Wang,Fei Wang,Ceng-lin Xu,Ye-ping Ruan,Yi Wang,Zhong Chen(Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Zhejiang Rehabilitation Medical Center,The Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310013,China;Institute of Pharmacology& Toxicology,College of Pharmaceutical Sciences,School of Medicine,Zhejiang University,Hangzhou 310058,China;Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Zhejiang Rehabilitation Medical Center,The Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310013,China;Institute of Pharmacology& Toxicology,College of Pharmaceutical Sciences,School of Medicine,Zhejiang University,Hangzhou 310058,China;Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province,School of Pharmaceutical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China;Institute of Pharmacology& Toxicology,College of Pharmaceutical Sciences,School of Medicine,Zhejiang University,Hangzhou 310058,China;Epilepsy Center,Second Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310009,China).Chemogenetic inhibition of subicular seizure-activated neurons alleviates cognitive deficit in male mouse epilepsy model[J].中国药理学报(英文版),2023,第12期
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Jia-wen Xu,Xu Xu,Yun Ling,Yan-chun Wang,Yu-jie Huang,Juan-zhen Yang,Jia-ying Wang,Xu Shen(Jiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases,Nanjing University of Chinese Medicine,Nanjing 210023,China;Jiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases,Nanjing University of Chinese Medicine,Nanjing 210023,China;Department of Otolaryngology Head and Neck Surgery & Center of Sleep Medicine,Shanghai Jiao Tong University Affiliated Sixth People's Hospital,Shanghai 200233,China;Jiangsu Key Laboratory of Drug Target and Drug for Degenerative Diseases,Nanjing University of Chinese Medicine,Nanjing 210023,China;National Key Laboratory on Technologies for Chinese Medicine Pharmaceutical Process Control and Intelligent Manufacture,Nanjing 210023,China).Vincamine as an agonist of G-protein-coupled receptor 40 effectively ameliorates diabetic peripheral neuropathy in mice[J].中国药理学报(英文版),2023,第12期
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Mei-jie Dai,Xing-xing Gui,Shu-miao Jia,Shu-ting Lv,Hao Dou,Wei Cui.DI-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog[J].中国药理学报(英文版),2023,第12期
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Li-guo Dong,Meng-qi An,Han-ying Gu,Li-ge Zhang,Jin-bao Zhang,Cheng-jie Li,Cheng-jie Mao,Fen Wang,Chun-feng Liu(Department of Neurology and Clinical Research Center of Neurological Disease,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China;Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience,Soochow University,Suzhou 215123,China;Department of Neurology,The Affiliated Hospital of Xuzhou Medical University,Xuzhou 221000,China;Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience,Soochow University,Suzhou 215123,China;Department of Neurology and Clinical Research Center of Neurological Disease,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China;Department of Neurology and Clinical Research Center of Neurological Disease,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China;Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience,Soochow University,Suzhou 215123,China;Department of Neurology and Clinical Research Center of Neurological Disease,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China;Jiangsu Key Laboratory of Neuropsychiatric Diseases and Institute of Neuroscience,Soochow University,Suzhou 215123,China;Department of Neurology,The Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830063,China).PACAP/PAC1-R activation contributes to hyperalgesia in 6-OHDA-induced Parkinson’s disease model rats via promoting excitatory synaptic transmission of spinal dorsal horn neurons[J].中国药理学报(英文版),2023,第12期
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(Department of Pharmacology,Shenyang Pharmaceutical University,Shenyang 110016,China).Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog[J].中国药理学报(英文版),2023,第12期
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Wang Mengdan,Zhang Shuo,Liu Xingyang,Wang Panpan,Zhu Yifan,Zhu Junrong,Lv Chongshan,Li Shiying,Liu Suifeng,Wen Lei.Salvianolic acid B ameliorates retinal deficits in an early-stage Alzheimer's disease mouse model through downregulating BACE1 and Abeta generation[J].中国药理学报,2023,第11期
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Zhu Xinxin,Wang Xia,Jiao Shiyu,Liu Ye,Shi Li,Xu Qing,Wang Jingjing,Chen Yuner,Zhang Qi,Song Yanting,Wei Ming,Yu Baoqi,Fielitz Jens,Gonzalez Frank J,Du Jie,Qu Aijuan.Cardiomyocyte peroxisome proliferator-activated receptor alpha prevents septic cardiomyopathy via improving mitochondrial function[J].中国药理学报,2023,第11期
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Zheng-yi Bao,Hui-min Li,Shuo-bo Zhang,Yi-qiu Fei,Ming-fei Yao,Lan-juan Li(State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310000,China;State Key Laboratory of Oncogenes and Related Genes,Shanghai Cancer Institute,Renji Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 201100,China;State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310000,China;Research Units of Infectious Disease and Microecology,Chinese Academy of Medical Sciences,Beijing 100010,China;State Key Laboratory for the Diagnosis and Treatment of Infectious Diseases,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310000,China;Research Units of Infectious Disease and Microecology,Chinese Academy of Medical Sciences,Beijing 100010,China;Jinan Microecological Biomedicine Shandong Laboratory,Jinan 250000,China).Administration of A.muciniphila ameliorates pulmonary arterial hypertension by targeting miR-208a-3p/NOVA1 axis[J].中国药理学报(英文版),2023,第11期
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Ke Gong,Zhen Zhang,Sha-sha Chen,Xin-ran Zhu,Meng-yao Wang,Xin-yue Yang,Chen Ding,Ji-hong Han,Qing-shan Li,Ya-jun Duan(Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes,Hefei University of Technology,Hefei 230031,China;Department of Cardiology,the First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230001,China;Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes,Hefei University of Technology,Hefei 230031,China;College of Life Sciences,State Key Laboratory of Medicinal Chemical Biology,Key Laboratory of Bioactive Materials of Ministry of Education,Nankai University,Tianjin 300071,China).6-Methyl flavone inhibits Nogo-B expression and improves high fructose diet-induced liver injury in mice[J].中国药理学报(英文版),2023,第11期
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Xiao-long Li,Xue-wu Liu,Wei-ling Liu,Yu-quan Lin,Jing Liu,Yu-sheng Peng,Li-min Cheng,Yan-hua Du(Department of Pharmacology,Cardiac & Cerebral Vascular Research Center,Zhongshan School of Medicine,Sun Yat-Sen University,Guangzhou 510080,China;State Key Laboratory of Organ Failure Research,National Clinical Research Center of Kidney Disease,Division of Nephrology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,China;Department of Pharmacology,Cardiac & Cerebral Vascular Research Center,Zhongshan School of Medicine,Sun Yat-Sen University,Guangzhou 510080,China;Zhujiang Hospital,Southern Medical University,Guangzhou 510280,China;Department of Pharmacology,Cardiac & Cerebral Vascular Research Center,Zhongshan School of Medicine,Sun Yat-Sen University,Guangzhou 510080,China;State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yat-sen University Cancer Center,Guangzhou 510060,China).Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission[J].中国药理学报(英文版),2023,第11期
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Ya-fei Deng,Shu-ting Wu,Hong-yan Peng,Lei Tian,Ya-na Li,Yao Yang,Meng Meng,Lan-lan Huang,Pei-wen Xiong,Song-yang Li,Qing-lan Yang,Li-li Wang,Xiao-yao Li,Li-ping Li,Xiu-lan Lu,Xiao-hui Li,Yan-ling Wei,Zheng-hui Xiao,Jian-hua Yu,You-cai Deng(Pediatrics Research Institute of Hunan Province and Hunan Provincial Key Laboratory of Children's Emergency Medicine,Hunan Children's Hospital,Changsha 410007,China;Department of Clinical Hematology,College of Pharmacy and Laboratory Medicine Science,Army Medical University,Chongqing 400038,China;Pediatrics Research Institute of Hunan Province and Hunan Provincial Key Laboratory of Children's Emergency Medicine,Hunan Children's Hospital,Changsha 410007,China;Department of Hematology and Hematopoietic Cell Transplantation,City of Hope National Medical Center,Los Angeles,CA,USA;Department of Clinical Hematology,College of Pharmacy and Laboratory Medicine Science,Army Medical University,Chongqing 400038,China;Department of Clinical Pharmacy,Weifang Traditional Chinese Hospital,Weifang 261041,China;Department of Gastroenterology,Chongqing Key Laboratory of Digestive Malignancies,Daping Hospital,Army Medical University,Chongqing 400042,China).mTORC2 acts as a gatekeeper for mTORC1 deficiency-mediated impairments in ILC3 development[J].中国药理学报(英文版),2023,第11期
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Mei-qi Zhang,Xin Jia,Cui-qin Cheng,Yu-xi Wang,Yi-ying Li,Ling-dong Kong,Qi-qi Li,Fang Xie,Yan-li Yu,Yu-ting He,Qiu-tong Dong,Zhan-hong Jia,Yao Wang,An-long Xu(School of Chinese Materia Medica,Beijing University of Chinese Medicine,Beijing 100029,China;School of Life Science,Beijing University of Chinese Medicine,Beijing 100029,China;School of Life Science,Beijing University of Chinese Medicine,Beijing 100029,China;National Key Laboratory of Efficacy and Mechanism on Chinese Medicine for Metabolic Diseases,Beijing University of Chinese Medicine,Beijing 100029,China).Capsaicin functions as a selective degrader of STAT3 to enhance host resistance to viral infection[J].中国药理学报(英文版),2023,第11期
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Joelle C.Boulos,Ejlal A.Omer,Daniela Rigano,Carmen Formisano,Manik Chatterjee,Ellen Leich,Sabine M.Klauck,Le-tian Shan,Thomas Efferth.Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma Open[J].中国药理学报(英文版),2023,第11期
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Zi-jian Zhang,Qi-fang Wu,An-qi Ren,Qian Chen,Jiang-zhou Shi,Jia-peng Li,Xi-yu Liu,Zhi-jie Zhang,Yu-zhe Tang,Yuan Zhao,Ning-ning Yao,Xiao-yu Zhang,Chang-peng Liu,Ge Dong,Jia-xuan Zhao,Mei-jun Xu,Yun-qiang Yue,Jia Hu,Fan Sun,Yu Liu,Qi-lin Ao,Fu-ling Zhou,Hong Wu,Tong-cun Zhang,Hai-chuan Zhu(Institute of Biology and Medicine,College of Life and Health Sciences,Wuhan University of Science and Technology,Wuhan 430065,China;Institute of Biology and Medicine,College of Life and Health Sciences,Wuhan University of Science and Technology,Wuhan 430065,China;School of Science,Wuhan University of Science and Technology,Wuhan 430065,China;Peking-Tsinghua Center for Life Sciences,and Academy for Advanced Interdisciplinary Studies,Peking University,Beijing 100871,China;The MOE Key Laboratory of Cell Proliferation and Differentiation,School of Life Sciences,Peking University,Beijing 100871,China;Department of Medical Records,Office for DRGs(Diagnosis Related Groups),Henan Cancer Hospital,Affiliated Cancer Hospital of Zhengzhou University,Zhengzhou 450003,China;Key Lab of Industrial Fermentation Microbiology of the Ministry of Education & Tianjin Key Lab of Industrial Microbiology,College of Biotechnology,Tianjin University of Science and Technology,Tianjin 300457,China;Institute of Pathology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Department of Pathology,School of Basic Medical Science,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Department of Hematology,Zhongnan Hospital of Wuhan University,Wuhan 430071,China;Institute of Biology and Medicine,College of Life and Health Sciences,Wuhan University of Science and Technology,Wuhan 430065,China;Key Lab of Industrial Fermentation Microbiology of the Ministry of Education & Tianjin Key Lab of Industrial Microbiology,College of Biotechnology,Tianjin University of Science and Technology,Tianjin 300457,China;Institute of Biology and Medicine,College of Life and Health Sciences,Wuhan University of Science and Technology,Wuhan 430065,China;College of Life Science,Wuchang University of Technology,Wuhan 430223,China;Synergy Innovation Center of Biological Peptide Antidiabetics of Hubei Province,College of Life Science,Wuchang University of Technology,Wuhan 430223,China).ATF4 renders human T-cell acute lymphoblastic leukemia cell resistance to FGFR1 inhibitors through amino acid metabolic reprogramming[J].中国药理学报(英文版),2023,第11期
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Han-lin Wang,Jia-nan Li,Wei-juan Kan,Gao-ya Xu,Guang-hao Luo,Ning Song,Wen-biao Wu,Bo Feng,Jing-feng Fu,Yu-tong Tu,Min-min Liu,Ran Xu,Yu-bo Zhou,Gang Wei,Jia Li(School of Pharmacy,Fudan University,Shanghai 210023,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;School of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210023,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;School of Pharmaceutical Science and Technology,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310000,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;School of Life Science and Biopharmaceutics,Shenyang Pharmaceutical University,Shenyang 110016,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;Schoolof Pharmaceutical Science,Jiangnan University,Wuxi 214122,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;School of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210023,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;School of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210023,China;Zhongshan Institute for Drug Discovery,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Zhongshan 528400,China;School of Pharmacy,Fudan University,Shanghai 210023,China;School of Pharmacy,Fudan University,Shanghai 210023,China;State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China;University of Chinese Academy of Sciences,Beijing 100049,China;School of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210023,China;School of Pharmaceutical Science and Technology,Hangzhou Institute for Advanced Study,University of Chinese Academy of Sciences,Hangzhou 310000,China;School of Life Science and Biopharmaceutics,Shenyang Pharmaceutical University,Shenyang 110016,China;Zhongshan Institute for Drug Discovery,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Zhongshan 528400,China).Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway[J].中国药理学报(英文版),2023,第11期
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Bin Zhang,Shao-han Xie,Jun-yi Hu,Si-jia Lei,Liang-hua Shen,Hong-tao Liu,Qing Zheng,Zhi-ming Zhang,Chun-lian Wu,Qiang Li,Feng Wang(Institute of Genomic Medicine,College of Pharmacy,Jinan University,Guangzhou 510632,China;State Key Laboratory of Bioactive Molecules and Druggability Assessment,Jinan University,Guangzhou 510632,China;International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education(MOE),College of Pharmacy,Jinan University,Guangzhou 510632,China;State Key Laboratory of Bioactive Molecules and Druggability Assessment,Jinan University,Guangzhou 510632,China;International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education(MOE),College of Pharmacy,Jinan University,Guangzhou 510632,China;Institute of Genomic Medicine,College of Pharmacy,Jinan University,Guangzhou 510632,China;State Key Laboratory of Bioactive Molecules and Druggability Assessment,Jinan University,Guangzhou 510632,China;College of Life Sciences,Zhengzhou University,No.100 Kexue Avenue,Zhengzhou 450001,China;State Key Laboratory of Bioactive Molecules and Druggability Assessment,Jinan University,Guangzhou 510632,China;Key Laboratory of Southwest China Wildlife Resources Conservation(China West Normal University),Ministry of Education,Nanchong 637009,China;Department of General Surgery,The First Affiliated Hospital,Jinan University,Guangzhou 510630,China;Department of General Surgery,Chaoshan Hospital,The First Affiliated Hospital of Jinan University,Chaozhou City 515600,China).Truncated SCRIB isoform promotes breast cancer metastasis through HNRNP A1 mediated exon 16 skipping[J].中国药理学报(英文版),2023,第11期
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