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Miyesaier Abudureyimu1,Mingjie Yang2,3,4,5,Xiang Wang1,Xuanming Luo6,Junbo Ge2,3,4,5,Hu Peng7,Yingmei Zhang2,3,4,5,Jun Ren2,3,4,5,8(Cardiovascular Department,Shanghai Xuhui Central Hospital,Fudan University;Department of Cardiology,Zhongshan Hospital,Fudan University,Shanghai Institute of Cardiovascular Diseases;Key Laboratory of Viral Heart Diseases,National Health Commission;Key Laboratory of Viral Heart Diseases,Chinese Academy of Medical Sciences;National Clinical Research Center for Interventional Medicine;Department of General Surgery Shanghai Xuhui Central Hospital,Fudan University;Department of Geriatrics,Shanghai Tenth Hospital,Tongji University;Department of Medical Laboratory and Pathology,University of Washington).Berberine alleviates myocardial diastolic dysfunction by modulating Drp1-mediated mitochondrial fission and Ca2+ homeostasis in a murine model of HFpEF[J].Frontiers of Medicine,2023,第6期
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Lu Liu1,2,Chenxia Zhou1,2,Huimin Jiang3,Huimin Wei4,Yifan Zhou3,Chen Zhou3,5,Xunming Ji2,3,6(Department of Neurology,Xuanwu Hospital,Capital Medical University;Neurology and Intracranial Hypertension and Cerebral Venous Disease Center,National Health Commission of China,Xuanwu Hospital,Capital Medical University;Beijing Institute of Brain Disorders,Capital Medical University;Beijing Advanced Innovation Center for Big Data-Based Precision Medicine,School of Biological Science and Medical Engineering,Beihang University;Department of Neurology,Beijing Shijitan Hospital,Capital Medical University;Department of Neurosurgery,Xuanwu Hospital,Capital Medical University).Epidemiology,pathogenesis,and management of coronavirus disease 2019-associated stroke[J].Frontiers of Medicine,2023,第6期
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Qiuyu Cao1,2,Yi Ding1,2,Yu Xu1,2,Mian Li1,2,Ruizhi Zheng1,2,Zhujun Cao3,Weiqing Wang1,2,Yufang Bi1,2,Guang Ning1,2,Yiping Xu4,Ren Zhao5(Department of Endocrine and Metabolic Diseases,Shanghai Institute of Endocrine and Metabolic Diseases,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine;Shanghai National Clinical Research Center for Metabolic Diseases,State Key Laboratory of Medical Genomics,Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission,Shanghai National Center for Translational Medicine,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine;Department of Infectious Disease,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine;Clinical Trials Center,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine;Department of General Surgery,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine).Small-molecule anti-COVID-19 drugs and a focus on China's homegrown mindeudesivir(VV116)[J].Frontiers of Medicine,2023,第6期
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Dong Wei1,Yusang Xie2,3,4,Xuefei Liu2,3,4,Rong Chen2,3,4,Min Zhou2,3,4,Xinxin Zhang1,Jieming Qu2,3,4(Department of Infectious Diseases,Research Laboratory of Clinical Virology,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine;Department of Pulmonary and Critical Care Medicine,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine;Institute of Respiratory Diseases,Shanghai Jiao Tong University School of Medicine;Shanghai Key Laboratory of Emergency Prevention,Diagnosis and Treatment of Respiratory Infectious Diseases).Pathogen evolution,prevention/control strategy and clinical features of COVID-19:experiences from China[J].Frontiers of Medicine,2023,第6期
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Meiling Xia1,2,Rui Yan2,Wenjuan Wang2,Meng Zhang2,Zhigang Miao2,Bo Wan2,Xingshun Xu1,2,3(Department of Neurology,The First Affiliated Hospital of Soochow University;Institute of Neuroscience,Soochow University;Jiangsu Key Laboratory of Neuropsychiatric Diseases,Soochow University).GID complex regulates the differentiation of neural stem cells by destabilizing TET2[J].Frontiers of Medicine,2023,第6期
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Linhua Zhao1,Chuanxi Tian1,2,Yingying Yang3,Huifang Guan4,Yu Wei1,2,Yuxin Zhang1,Xiaomin Kang1,2,Ling Zhou1,Qingwei Li1,Jing Ma4,Li Wan1,2,Yujiao Zheng5,Xiaolin Tong1(Institute of Metabolic Diseases,Guang'anmen Hospital,China Academy of Chinese Medical Sciences;Beijing University of Chinese Medicine;National Center for Integrative Medicine,China-Japan Friendship Hospital;College of Traditional Chinese Medicine,Changchun University of Chinese Medicine;College of Traditional Chinese Medicine,Anhui University of Chinese Medicine).Practice and principle of traditional Chinese medicine for the prevention and treatment of COVID-19[J].Frontiers of Medicine,2023,第6期
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Jie Shao1,Wenjuan Wang2,Baorui Tao1,Zihao Cai1,Haixia Li2,Jinhong Chen1(Department of General Surgery Huashan Hospital,Fudan University;Department of Pathology Huashan Hospital,Fudan University).Extracellular vesicle-carried GTF21 from mesenchymal stem cells promotes the expression of tumor-suppressive FAT1 and inhibits stemness maintenance in thyroid carcinoma[J].Frontiers of Medicine,2023,第6期
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Zhichen Jiang1,2,Xiaohao Zheng3,4,Min Li5,Mingyang Liu1(State Key Laboratory of Molecular Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of General Surgery,Division of Gastroenterology and Pancreas,Zhejiang Provincial People's Hospital,Affiliated People's Hospital,Hangzhou Medical College;Department of Pancreatic and Gastric Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of General Surgery Beijing Friendship Hospital,Capital Medical University;Department of Medicine,The University of Oklahoma Health Sciences Center).Improving the prognosis of pancreatic cancer:insights from epidemiology,genomic alterations,and therapeutic challenges[J].Frontiers of Medicine,2023,第6期
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Xinyue Zhao1,Haijun Ge1,Wenshuai Xu1,Chongsheng Cheng2,Wangji Zhou2,Yan Xu2,Junping Fan2,Yaping Liu1,Xinlun Tian2,Kai-Feng Xu2,Xue Zhang1(McKusick-Zhang Center for Genetic Medicine,State Key Laboratory of Medical Molecular Biology Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences & Peking Union Medical College;Department of Pulmonary and Critical Care Medicine,State Key Laboratory of Complex Severe and Rare Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College).Lack of CFAP54 causes primary ciliary dyskinesia in a mouse model and human patients[J].Frontiers of Medicine,2023,第6期
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Yuntao Zhang1,Yuxiu Zhao1,Hongyang Liang1,Ying Xu1,Chuge Zhou1,Yuzhu Yao1,Hui Wang1,Xiaoming Yang1,2(China National Biotec Group Company Limited;National Engineering Technology Research Center of Combined Vaccines).Innovation-driven trend shaping COVID-19 vaccine development in China[J].Frontiers of Medicine,2023,第6期
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Xiaoming Yang1,2,3(National Engineering Technology Research Center for Combined Vaccines;Wuhan Institute of Biological Products Co.Ltd.;China National Biotec Group Company Limited).Passive antibody therapy in emerging infectious diseases[J].Frontiers of Medicine,2023,第6期
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Guangbiao Zhou1,Saijuan Chen2,Zongjiu Zhang3,Zhu Chen2(State Key Laboratory of Molecular Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Medical Genomics,Shanghai Institute of Hematology,National Research Center for Translational Medicine (Shanghai),Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine;Institute for Hospital Management,Tsinghua University).Revisiting China's response to coronavirus disease 2019[J].Frontiers of Medicine,2023,第6期
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Tiantian Li1,Dongsheng Wang2,Haiming Wei3,4,Xiaoling Xu2(Department of Geriatric Medicine,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China;Respiratory and Critical Care Medicine,The First Affiliated Hospital of USTC,Division of Life Sciences and Medicine,University of Science and Technology of China;Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease,School of Life Science and Medical Center,University of Science and Technology of China;Hefei National Laboratory for Physical Sciences at Microscale,University of Science and Technology of China).Cytokine storm and translating IL-6 biology into effective treatments for COVID-19[J].Frontiers of Medicine,2023,第6期
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Beibei Jiang1,Tong Zhang1,Minjuan Deng2,Wei Jin2,Yuan Hong1,Xiaotong Chen1,Xin Chen1,Jing Wang1,Hongjia Hou1,Yajuan Gao1,Wenfeng Gong1,Xing Wang1,Haiying Li1,Xiaosui Zhou1,Yingcai Feng1,Bo Zhang1,Bin Jiang2,Xueping Lu2,Lijie Zhang2,Yang Li2,Weiwei Song2,Hanzi Sun1,Zuobai Wang3,Xiaomin Song1,Zhirong Shen2,Xuesong Liu1,Kang Li4,Lai Wang1,Ye Liu1(Department of Biology,BeiGene (Beijing) Co.Ltd.;Department of Discovery Biomarkers,BeiGene (Beijing) Co.Ltd.;Department of Clinic Development,BeiGene (Beijing) Co.Ltd.;Department of Biologics,BeiGene (Beijing) Co.Ltd.).BGB-A445,a novel non-ligand-blocking agonistic anti-OX40antibody,exhibits superior immune activation and antitumor effects in preclinical models[J].Frontiers of Medicine,2023,第6期
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Miaomiao Zhu1,2,3,Huamin Liang1,2,3,Zhe Zhang1,Hao Jiang1,2,3,Jingwen Pu1,2,3,Xiaoyi Hang1,2,3,Qian Zhou1,2,3,Jiacheng Xiang1,2,3,Ximiao He1,2,3(Department of Physiology,School of Basic Medicine,Tongji Medical College,Huazhong University of Science and Technology;Center for Genomics and Proteomics Research,School of Basic Medicine,Tongji Medical College,Huazhong University of Science and Technology;Hubei Key Laboratory of Drug Target Research and Pharmacodynamic Evaluation,Huazhong University of Science and Technology).Distinct mononuclear diploid cardiac subpopulation with minimal cell-cell communications persists in embryonic and adult mammalian heart[J].Frontiers of Medicine,2023,第5期
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Chong Li1,Xinyi Li1,Ke He1,Yang Wu1,Xiaoming Xie1,Jiju Yang1,Fan Zhang1,Yang Yue1,Huifeng Hao2,Shaokun Zhao3,Xin Li3,Guihua Tian1(Dongzhimen Hospital,Beijing University of Chinese Medicine;Department of Integration of Chinese and Western Medicine,Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing),Peking University Cancer Hospital & Institute;State Key Laboratory of Cognitive Neuroscience and Learning,Beijing Normal University).Discovery of the mechanisms of acupuncture in the treatment of migraine based on functional magnetic resonance imaging and omics[J].Frontiers of Medicine,2023,第5期
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Dawei Xie1,Zheng Wang1,Beibei Sun1,Liwei Qu2,Musheng Zeng3,Lin Feng4,Mingzhou Guo4,Guizhen Wang1,Jihui Hao5,Guangbiao Zhou1(State Key Laboratory of Molecular Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;State Key Laboratory of Membrane Biology,Institute of Zoology,Chinese Academy of Sciences & University of Chinese Academy of Sciences;State Key Laboratory of Oncology in South China,Sun Yat-sen University Cancer Center;Department of Gastroenterology & Hepatology and Department of Pathology,Chinese People's Liberation Army General Hospital;Department of Pancreatic Cancer,Tianjin Medical University Cancer Institute and Hospital,National Clinical Research Center for Cancer,Key Laboratory of Cancer Prevention and Therapy,Tianjin's Clinical Research Center for Cancer).High frequency of alternative splicing variants of the oncogene Focal Adhesion Kinase in neuroendocrine tumors of the pancreas and breast[J].Frontiers of Medicine,2023,第5期
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Liming Liao,Huilin Xu,Yuhan Zhao,Xiaofeng Zheng(State Key Laboratory of Protein and Plant Gene Research,Department of Biochemistry and Molecular Biology,School of Life Sciences,Peking University).Metabolic interventions combined with CTLA-4 and PD-1/PD-L1 blockade for the treatment of tumors:mechanisms and strategies[J].Frontiers of Medicine,2023,第5期
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Elias A.T.Koch1,2,3,4,Anne Petzold1,2,3,4,Anja Wessely1,2,3,4,Edgar Dippel5,Markus Eckstein2,3,4,6,Anja Gesierich7,Ralf Gutzmer8,Jessica C.Hassel9,Harald Knorr10,Nicole Kreuzberg11,Ulrike Leiter12,Carmen Loquai13,Friedegund Meier14,Markus Meissner15,Peter Mohr16,Claudia Pf?hler17,Farnaz Rahimi18,Dirk Schadendorf19,Max Schlaak20,Kai-Martin Thoms21,Selma Ugurel22,Jochen Utikal23,Michael Weichenthal2,3,Beatrice Schuler-Thurner1,2,3,4,Carola Berking1,2,3,4,Markus V.Heppt1,2,3,4(Department of Dermatology,Uniklinikum Erlangen,Friedrich-Alexander-University Erlangen-Nürnberg (FAU);Comprehensive Cancer Center Erlangen-European Metropolitan Area of Nurnberg (CCC ER-EMN);Deutsches Zentrum Immuntherapie (DZI),Uniklinikum Erlangen,Friedrich-Alexander-University Erlangen-Nürnberg (FAU);Bavarian Cancer Research Center (BZKF),Uniklinikum Erlangen;Department of Dermatology,Ludwigshafen Medical Center;Institute of Pathology,Uniklinikum Erlangen,Friedrich-Alexander-University Erlangen-Nürnberg;Department of Dermatology,University Hospital Würzburg;Skin Cancer Center Minden,Department of Dermatology,Mühlenkreiskliniken A?R,Ruhr University Bochum Campus Minden;Skin Cancer Center,Department of Dermatology and National Center for Tumor Diseases (NCT),University Hospital Heidelberg;Department of Ophthalmology,Uniklinikum Erlangen,Friedrich-Alexander-University Erlangen-Nurnberg (FAU);Department of Dermatology and Venereology,Skin Cancer Center at the Center of Integrated Oncology (CIO) K?ln Bonn,University,Hospital of Cologne;Department of Dermatology,Center for Dermatooncology,University Hospital Tübingen;Department of Dermatology,University Medical Center Mainz;Skin Cancer Center at the University Cancer Center Dresden and National Center for Tumor Diseases & Department of Dermatology,University Hospital Carl Gustav Carus;Department of Dermatology,Venereology and Allergology,Goethe University;Department of Dermatology;Department of Dermatology,Saarland University Medical School;Department of Dermatology and Allergy,Munich University Hospital (LMU);Department of Dermatology,University Hospital Essen,45147 University Duisburg-Essen,German Cancer Consortium (DKTK);Charité—Universit?tsmedizin Berlin,Corporate Member of Freie Universit?t Berlin,Humboldt-Universit?t zu Berlin,Berlin Institute of Health,Department of Dermatology,Venerology and Allergology;Department of Dermatology,University Medical Center Goettingen;Skin Cancer Unit,German Cancer Research Center (DKFZ) and Department of Dermatology,Venereology and Allergology,University Medical Center Mannheim,Ruprecht-Karl University of Heidelberg,DKFZ Hector Cancer Institute at the University Medical Center Mannheim;Department of Dermatology University Hospital Schleswig-Holstein).Liver-directed treatment is associated with improved survival and increased response to immune checkpoint blockade in metastatic uveal melanoma:results from a retrospective multicenter trial[J].Frontiers of Medicine,2023,第5期
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Quanjin Li1,2,Pu Gao1,2(CAS Key Laboratory of Infection and Immunity,National Laboratory of Biomacromolecules,CAS Center for Excellence in Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences;University of Chinese Academy of Sciences).Phase separation in cGAS-STING signaling[J].Frontiers of Medicine,2023,第5期
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Nuo Si,Guoqin Zhan,Xiaolu Meng,Zeya Zhang,Xin Huang,Bo Pan(Plastic Surgery Hospital,Peking Union Medical College and Chinese Academy of Medical Sciences).Identification of novel mutations in EYA3 and EFTUD2 in a family with craniofacial microsomia:evidence of digenic inheritance[J].Frontiers of Medicine,2023,第5期
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Liguo Wang1,Zhouli Yang1,Guangchen Li1,Yongbo Liu1,Chao Ai2,Yu Rao1(MOE Key Laboratory of Protein Sciences,School of Pharmaceutical Sciences,MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology,Tsinghua University;Beijing Tsinghua Changgung Hospital,School of Clinical Medicine,Tsinghua University).Discovery of small molecule degraders for modulating cell cycle[J].Frontiers of Medicine,2023,第5期
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Pengfei Zhao1,Yating Wang2,Xiao Yu1,Yabing Nan1,Shi Liu1,Bin Li2,Zhumei Cui3,Zhihua Liu1(State Key Laboratory of Molecular Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Gynecological Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College;Department of Obstetrics and Gynecology,The Affiliated Hospital of Qingdao University).Long noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR-627-3p/SPRED1 axis[J].Frontiers of Medicine,2023,第5期
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Zhiqian Bi1,Jia Chen1,Xiaoyao Chang1,Dangran Li1,Yingying Yao1,Fangfang Cai1,2,Huangru Xu1,Jian Cheng3,Zichun Hua1,4,2,Hongqin Zhuang1(The State Key Laboratory of Pharmaceutical Biotechnology,College of Life Sciences,Nanjing University;School of Biopharmacy,China Pharmaceutical University;Institute of Neuroscience,Soochow University;Changzhou High-Tech Research Institute of Nanjing University and Jiangsu TargetPharma Laboratories Inc.).ADT-OH improves intestinal barrier function and remodels the gut microbiota in DSS-induced colitis[J].Frontiers of Medicine,2023,第5期
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Xianggui Yuan1,Teng Yu1,Jianzhi Zhao1,Huawei Jiang1,Yuanyuan Hao1,Wen Lei1,Yun Liang1,Baizhou Li2,Wenbin Qian1,3,4(Department of Hematology,the Second Affiliated Hospital,Zhejiang University School of Medicine;Department of Pathology,the Second Affiliated Hospital,Zhejiang University School of Medicine;National Clinical Research Center for Hematologic Diseases,the First Affiliated Hospital of Soochow University;Cancer Institute (Key Laboratory of Cancer Prevention and Intervention,China National Ministry of Education),the Second Affiliated Hospital of Zhejiang University School of Medicine).Analysis of the genomic landscape of primary central nervous system lymphoma using whole-genome sequencing in Chinese patients[J].Frontiers of Medicine,2023,第5期
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Rongchun Wang1,2,3,Danhui Yang1,2,3,Chaofeng Tu4,5,Cheng Lei1,2,3,Shuizi Ding1,2,3,Ting Guo1,2,3,Lin Wang1,2,3,Ying Liu1,2,3,Chenyang Lu1,2,3,Binyi Yang1,2,3,Shi Ouyang6,Ke Gong7,Zhiping Tan8,Yun Deng6,Yueqiu Tan4,5,Jie Qing1,2,3,Hong Luo1,2,3(Department of Pulmonary and Critical Care Medicine,The Second Xiangya Hospital of Central South University;Research Unit of Respiratory Disease,Central South University;Hunan Diagnosis and Treatment Center of Respiratory Disease;Institute of Reproductive and Stem Cell Engineering,NHC Key Laboratory of Human Stem Cell and Reproductive Engineering,School of Basic Medical Science,Central South University;Clinical Research Center for Reproduction and Genetics in Hunan Province,Reproductive and Genetic Hospital of CITIC-Xiangya;Zebrafish Genetics Laboratory,College of Life Sciences,Hunan Normal University;Department of Cardiovascular Surgery,The Second Xiangya Hospital of Central South University,Central South University;Clinical Center for Gene Diagnosis and Therapy,Department of Cardiovascular Surgery,The Second Xiangya Hospital of Central South University).Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice[J].Frontiers of Medicine,2023,第5期
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Kanchana Ngaosuwan1,Kamonwan Soonklang2,Chawin Warakul1,Chirayu Auewarakul1,Nithi Mahanonda3(Princess Srisavangavadhana College of Medicine,Chulabhorn Royal Academy;Data Management Unit,Centre of Learning and Research in Celebration of HRH Princess Chulabhorn's 60th Birthday Anniversary,Chulabhorn Royal Academy;Chulabhorn Hospital,Chulabhorn Royal Academy).Protection of inactivated vaccine against SARS-CoV-2 infections in patients with comorbidities:a prospective cohort study[J].Frontiers of Medicine,2023,第5期
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Gang Lu1,Yun Ling2,Minghao Jiang1,Yun Tan1,Dong Wei3,Lu Jiang1,Shuting Yu1,Fangying Jiang1,Shuai Wang1,Yao Dai1,Jinzeng Wang1,Geng Wu4,Xinxin Zhang3,Guoyu Meng1,Shengyue Wang1,Feng Liu1,Xiaohong Fan2,Saijuan Chen1(Shanghai Institute of Hematology National Research Center for Translational Medicine,State Key Laboratory of Medical Genomics,Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine;Shanghai Public Health Clinical Center,Fudan University;Department of Infectious Diseases,Research Laboratory of Clinical Virology,National Research Center for Translational Medicine,Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine;State Key Laboratory of Microbial Metabolism,School of Life Sciences and Biotechnology,The Joint International Research Laboratory of Metabolic and Developmental Sciences,Shanghai Jiao Tong University).Primary assessment of the diversity of Omicron sublineages and the epidemiologic features of autumn/winter 2022 COVID-19 wave in Chinese mainland[J].Frontiers of Medicine,2023,第4期
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Jiaqi Dai1,2,Tao Wang3,Ke Xu1,2,Yang Sun1,2,Zongzhe Li1,2,Peng Chen1,2,Hong Wang2,Dongyang Wu2,Yanghui Chen2,Lei Xiao2,Hao Liu2,Haoran Wei2,Rui Li1,2,Liyuan Peng1,Ting Yu1,Yan Wang1,2,Zhongsheng Sun3,Dao Wen Wang1,2(Division of Cardiology Department of Internal Medicine,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology;Hubei Key Laboratory of Genetics and Molecular Mechanism of Cardiologic Disorders,Huazhong University of Science and Technology;Beijing Institutes of Life Science,Chinese Academy of Sciences).Machine learning modeling identifies hypertrophic cardiomyopathy subtypes with genetic signature[J].Frontiers of Medicine,2023,第4期
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